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M A LESSLER

Publications and source records attributed to M A LESSLER.

9 recordsLinked to original sources

Molecular changes in deoxyribonucleic acid induced by X-rays.

A chromatographic study of molecular changes in DNA after in vitro exposure to x-rays revealed little effect on the DNA macromolecule when either intact red cells of frog or DNA isolated from these cells was exposed to 1000 r. Increasing the dose to 10,000 r resulted in a significant shift from gradients of lower molecular weight to the higher gradients. These data suggest that cross-linking of DNA occurred at the higher radiation level.

DNA↗

Low-level x-ray damage to amphibian erythrocytes.

In vitro x-irradiation of frog and Amphiuma erythrocytes caused cytophysiological damage to part of the cell population. There was a significant decrease in the percentage of normal cells and some hemolysis. Changes were also observed in the electrical capacitance and potassium-42 uptake of irradiated erythrocytes.

Amphibians↗