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Biomedical subjects

M A Lassrich

Publications and source records attributed to M A Lassrich.

At least 19 recordsLinked to original sources
PubMed1986

[Roentgen diagnosis of inflammatory bowel diseases in the child].

Inflammatory diseases of the bowel, especially of the small bowel, frequently present with vague symptoms in children. In many cases X-ray examination enables diagnosis, differentiation and localization of such diseases, as well as follow up and detection of complications. In the hand of the experienced radiologist the exposure to X-rays is very low. Radiological signs are demonstrated according to the most important inflammatory disease entities.

Child↗
PubMed1983

Epidermoids and dermoids of the calvarian bones in early childhood: their behaviour in the growing skull.

Thirteen out of 25 cystic lesions of the infantile skull, radiographically classified as epidermoids or dermoids of the calvarian bones, disappeared spontaneously during early childhood. A further six lesions showed involution. In all, 19/25 lesions were involutive. In no case did we find an enlargement which could be attributed with certainly, to growth after the age of 3 years. These findings strongly support the opinion of Fauré that by far most of these lesions are non-evolutive and generally do not need surgical treatment. Only lesions which do persist beyond the third year of life and grow continuously or begin to grow again need to be operated. Thus, we recommend a conservative attitude and a radiographic follow-up at long intervals.

Child, Preschool↗
PubMed1981

[Fundamental facts on dosimetry in the assessment of radioexposure and risk of such exposure in children (author's transl)].

Various methods for determining exposure to radiation are critically reviewed on the basis of 358 x-ray examinations of children (218 cardiac catheters with angiocardiography, 39 gastrointestinal examinations, 101 urological examinations). It is shown that the surface dose is an insufficient parameter for the actual exposure of the child to radiation. Estimates of the radiation risk based thereon are misleading. Even the determination of the area dose product and the integral dose alone will not allow any valid comparison of the exposure in different age groups. The important factor for an accurate determination of the somatic radiation risk is the ratio of integral dose to the body mass (mean body dose), since this is the only factor which is independent of body variables, i.e. only this figure will yield the relation of radiation risks in different age groups. Independent of the examination methods, a higher radiation risk must be assumed in infants than in older children or adults. These relationships are demonstrated on the basis of the author's own measurements and calculations.

Adolescent↗
PubMed1980

[Radiation-risk in catheterization and angiocardiography of the child (author's transl)].

The skin exposure and the energy transferred to the body (integraldose) increase with the child's growth. Nevertheless the mean body dose (integraldose/body-weight) is the highest in the youngest patient. The probability of roentgenray induced letal malignancy is approximately 1:9000--1:17000. The morbidity risk may be 2--3 times higher at the least.

Adolescent↗
PubMed1980

[Radiation risk for the child in urinary tract roentgendiagnostic (author's transl)].

During one urogramm skin doses were measured between 0,1--0,9 Roentgen (R) in the radiation field. The testes dose was 6--41 mR. In mictioncysto-urethrography the skin dose was between 0,2 and 4,2 R/examination, and the testes dose 50--80 mR. The energy transferred to the body by the X-rays (integral dose) was 5,6--23 mJoule (mJ) per urogramm. The mean-body-dose (integral dose/bodyweight) was 1,3--0,6 mJ/kg per examination. The probability to induce a lethal disease (for example leukemia or malignoma) by this dose is approximately 1:50 000--1:500 000. The probability that exposure of the gonades induces mutations and thereby malformations in the following two generations is equally about 1:50 000--1:500 000.

Adolescent↗
PubMed1979

[Twenty years of urology in a children's hospital (1954--1974). Together with an epicrisis of 101 children with bilateral anomalies of the urinary passages, operated on in the first year of life (author's transl)].

This work encompasses a 20-year period, during which a urologist spent an important part of his time in a children's hospital, because of his conviction that attemps at effective treatment of urinary passage anomalies in childhood have a chance only when treatment is begun as early as possible. A report is presented on 101 children with bilateral, severe urinary passage anomalies, who were operated on in the first year of life, with the goal of early, total correction. The following experiences are of general significance: 1. The earlier the symptoms -- in 90% of cases, pyuria -- the more severe are the findings. -- 2. Males are primarily affected, here at a ratio of 7:3. As a result, pyuria in infants must be explained urologically, particularly when it occurs in males. -- This report is a plea for early, total correction and against periodic urinary drainage. Results show a 50% decrease in infections, flow disturbances, and biochemical changes, as well as a postoperative burst of growth also in 50% of cases. Cinematographic examinations show normal peristalsis even after skeletization and drastic reduction of a megaureter. The mortality was 9%, in the first year of life, 6%. Surprisingly, the result was not influenced by the presence or absence of reflux, but rather by stigmas and inferior development. Reflux had probably already played its fateful part in this severe bilateral disease, so that antireflux plastic surgery loses its prophylactic value. Compared with reports of experiences with periodic urinary drainage, our aim is to disprove the argument that, in difficult cases, total correction is dangerous: on the contrary, our results are better and coincide with the experiences of Hendren. Although Bischoff did not live to see the results of this work, in retrospect, our results bear out his pioneering concepts and ideas.

Child↗
PubMed1978

[Ulcerative and granulomatous colitis in children (author's transl)].

Colitis ulcerosa and colitis granulomatosa (Morbus Crohn) are closely related diseases, and are known as unspecific colitis. Yet it is important though difficult to distinguish between these two forms since prognosis and therapy are different. Both forms require a careful follow-up over a long time because late complications are possible even in cases of clinical remission.

Adolescent↗