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Biomedical subjects

M A Meyers

Publications and source records attributed to M A Meyers.

At least 19 recordsLinked to original sources

Demographic, social and stress correlates of hypertension among the urban poor.

The relationship of demographic, social, and psychological variables to the diagnosis of hypertension in a population of urban, poor, predominantly black out-patients is reported. Subjects were 182 patients presenting for health care at Wayne State University Family Practice Clinic. Age, race, marital status, attendance at religious services, education, employment status, income, source of income and interpersonal stress were significantly related to a diagnosis of hypertension in this sample. Of those characteristics found to be significantly related to hypertension, discriminative analysis showed that age, race, education and frequency of church attendance were most important in predicting a diagnosis of hypertension among this out-patient sample of the urban poor. Implications for clinical care and for future research needs are considered.

Adolescent

Grey Turner's sign and Cullen's sign in acute pancreatitis.

Four patients with acute pancreatitis presenting with Grey Turner's sign or Cullen's sign have been studied by computed tomography (CT). These observations help confirm the precise anatomic pathways by which the extravasated pancreatic enzymes and their effects lead to these cutaneous discolorations. Grey Turner's sign is produced by spread from the anterior pararenal space to between the two leaves of the posterior renal fascia and subsequently to the lateral edge of the quadratus lumborum muscle. Communication may be established to the posterior pararenal space and to the structures of the flank wall. The lumbar triangle, a site of anatomic weakness on the flank wall, may serve as a structural predisposition. Cullen's sign can be seen to be secondary to the tracking of liberated pancreatic enzymes to the anterior abdominal wall from the inflamed gastrohepatic ligament and across the falciform ligament. Another more direct pathway may be extension from inflammatory changes of the small mesentery or greater omentum to the round ligament, and then to properitoneal fat deep to the umbilicus.

Abdomen

Imaging the direct bidirectional spread of disease between the abdomen and the female pelvis via the subperitoneal space.

This report expands the concept of the subperitoneal space (SS) as the potential conduit for direct spread of disease in the abdomen to include the female pelvis. The normal anatomy of the SS in the lower abdomen, the female pelvis, and its uninterrupted continuation between the abdomen and pelvis are demonstrated by several imaging modalities. Surgically proven cases of bidirectional spread of disease between the abdomen and female pelvis are reported. The unifying concept of the interrelationship formed by the SS provides an understanding of the basic concepts of the pathways of direct spread of disease and the pathogenesis of the clinical presentation of disease distant from its site of origin.

Abdomen

Representation of the black elderly in Detroit metropolitan nursing homes.

This paper presents the results of an analysis of the distribution of black elderly patients in the long-term care systems of Detroit City, Wayne, and Oakland counties, Michigan. These areas were chosen because of their proximity to Wayne State University and because Detroit has a large black population. Wayne and Oakland counties are largely suburban areas. Black, long-term care utilization was compared with the black elderly representation of the base population in these three locations. The sex-specific distribution between whites and blacks in long-term care populations revealed that black men utilized the greatest amount of long-term care and were more dependent on Medicaid. One hundred twenty-one licensed nursing homes were contacted by telephone and a follow-up questionnaire was sent to the respondents during the five-month study périod.It has been observed nationally that the elderly black population is underrepresented in the long-term care system. The findings obtained in this study, however, are not in agreement with the national trend. In Detroit, the black elderly are represented in nursing homes in approximate proportion to their representation in the larger community.This analysis raises questions of need vs utilization of long-term care by the black elderly in urban areas. This is the first study of black elderly long-term care representation in a specific urban area in the United States.

Black or African American

The peritoneal ligaments and mesenteries: pathways of intraabdominal spread of disease.

The abdomen has been conveniently divided anatomically and clinically into specific intraperitoneal and extraperitoneal sites. A recognition of the pathways of spread and localizing features of infections, malignancies, and traumatic collections has immeasurably extended diagnostic imaging capabilities. Yet, while the abdomen may be visualized as subdivided into compartments, it must also be essentially appreciated that these compartments are an actual or potential interconnecting network. In the upper abdomen peritoneal reflections comprise 11 major ligaments and mesenteries. These are generally readily recognizable on computed tomographic scans by either their typical location and organ relationships or the landmarks provided by their major constituent vessels. These ligaments and mesenteries provide continuity of anatomic planes, which permits the spread of disease between intraperitoneal compartments, between extraperitoneal spaces, and between intraperitoneal and extraperitoneal localized sites.

Gastrointestinal Diseases

Kaposi's sarcoma of the intestinal tract: roentgen manifestations.

Five cases of generalized Kaposi's sarcoma are reported with roentgen evidence of involvement of the intestinal tract. In three instances, there was extensive involvement of the small bowel with multiple intramural nodules. The fourth patient demonstrated multiple polypoid lesions of the colon, and in the fifth a constricting lesion of the ileum was present. Two patients with small bowel involvement had significant malabsorption. This latter complication of diffuse Kaposi's sarcoma of the small bowel has not been previously reported. The diagnosis of the nature of the roentgen intestinal abnormality can usually be made, because intestinal involvement generally occurs late in the disease, when both extensive cutaneous nodules and edema of the extremities are apparent.

Aged

Calcified primary tumors of the gastrointestinal tract.

The dominant pattern and location of calcifications occurring within 23 primary gastrointestinal tumors have been analysed and correlated with the data from the literature. The provided guidelines for radiologic diagnosis of such calcified tumors include: (1) a retrocardiac mass containing amorphous calcifications is typical of leiomyoma of the esophagus; (2) calcific deposits similar to that in uterine fibroids may be the feature of gastric leiomyoma or intestinal leiomyosarcoma; (3) sand-like deposits within the wall of the stomach or colon are characteristic of a mucinous adenocarcinoma; (4) clusters of phleboliths in the gastrointestinal wall suggest a hemangioma particularly if recurrent intestinal bleeding and cutaneous hemangiomas are associated; (5) sunburst type of calcification in the pancreas indicates a cystadenoma or cystadenocarcinoma of that organ; and (6) aggregates of granular calcifications in the liver are diagnostic for metastatic adenocarcinoma of the colon but may rarely be seen in a primary malignancy of the liver.

Adenocarcinoma

Pathogenesis of diverticulitis complicating granulomatous colitis.

The involement of diverticula by granulomatous colitis may cause an increased incidence of diverticulitis. Of 21 patients with Crohn's disease and associated diverticulosis who underwent resection, sigmoid diverticulitis was pathologically confirmed in 10 (48%). The clinical recognition of the coexistence of the two diseases is often difficult. The radiological signs of peridiverticulitis complicating granulomatous colitis usually show clear evidence of the underlying pathological changes. They include localized diverticular performation, perhaps with multiple communications via a paracolonic sinus tract, mass pressure from the paracolicabscess, and occasionally some degree of communication with deep fissuring ulcers of Crohn's disease. Because diverticula breach the colonic wall, histological analysis confirm that their involvement by the transmural process of granulomatous colitis predisposes to peridiverticulitis and/or abscess formation.

Aged

Ischemic disease of the small bowel and colon associated with oral contraceptives.

The widespread use of hormonal contraceptive pills by young women has caused a documented increase in thromboembolic disorders. This article describes yet another of the drug-induced complications namely, the development of ischemic bowel disease in seven cases. The ischemic changes which involved the small intestine in three and the colon in four patients became reversible after conservative management and discontinuance of oral contraceptive agents. The importance of clinical and radiologic consideration of ischemic bowel disease in young females receiving birth control pills is emphasized.

Adult

Complications of gastrointestinal fiberoptic endoscopy.

Flexible fiberoptic endoscopes are being increasingly used for direct visualization and biopsy of lesions of the gastrointestinal tract. The spectrum of gastrointestinal complications associated with fiber-optic esophagoscopy, gastroscopy, and colonoscopy is reviewed. Radiologic recognition and evaluation of these iatrogenic incidents is of critical importance.

Colon

Pneumatosis intestinalis.

Pneumatosis intestinalis is a usually benign condition which may affect any segment of the gastrointestinal tract from the stomach to rectum. Occasionally, however, it may be a grave prognostic sign. This article presents the spectrum of diagnostic radiographic features of the entity with emphasis on differentiation of the underlying etiologic factors. Representative examples of pneumatosis intestinalis complicating various gastrointestinal disorders are illustrated.

Adult

Colonic ileus.

Nine cases of colonic ileus, characterized by selective or disproportionate distention of the large intestine without organic obstruction, are detailed. Massive cecal dilatation often dominates the radiographic presentation and may portend perforation. While management is generally conservative, cecostomy may be necessary to prevent peritonitis.

Adult

The neonatal colon: an anatomic approach to plain films.

An appreciation of haustral anatomy as well as the anatomic relationships of the colon serve as the basis of plain film colon identification in the patient beyond infancy. An evaluation of the newborn colon in the normal state and with low colonic obstruction indicates that these principles apply here as well. Newborns with suspected intestinal obstruction should be studied in multiple projections early in their clinical course. A search should be made for haustrations and characteristic anatomic relationships of the colon, as well as gas in the rectum. Although clear differentiation of large from small bowel obstruction may not always be possible, these principles should serve as a basis for a systematic approach to the newborn abdominal plain film.

Colon

Ischemic colitis associated with sigmoid volvulus: new observations.

Ischemic colitis following conservative management of sigmoid volvulus is documented in four cases. Repeat barium enema studies in these patients showed characteristic "thumbprinting", transverse ridging, and mucosal ulcerations within a segment or the entire length of the sigmoid, lasting up to 7 days after nonoperative decompression. The development, extent, and severity of the ischemic changes seem to correlate with the degree of volvulus, blockage of venous and arterial circulation in the sigmoid mesocolon, and increased intraluminal pressure.

Adult

Progression of Menetrier's disease with postoperative gastrojejunal intussusception.

A unique case of Menetrier's disease of the stomach with long term follow-up is presented to document progression of extent of the disease radiologically and pathologically. This observation provides an insight into the natural history of the condition and suggests that local excision is not necessarily curative. In addition, this case demonstrates the complication of preoperative direct prolapse of involved gastric mucosa through the pylorus, and subsequent postoperative antegrade intussusception of the progressively involved gastric mucosa across a Billroth II gastrojejunostomy.

Adult