Biomedical subjects

M A Monakhova

Publications and source records attributed to M A Monakhova.

15 recordsLinked to original sources

PubMed1990

[The spatial reorganization of the perinucleolar area of hematopoietic cells in human leukemias].

The structure of perinucleolar zone in nuclei of peripheral blood hemopoietic cells has been studied. The cells of human patient with chronic lympholeukemia, chronic myeloleukemia, various forms of acute leucosis have been investigated. The phenomenon of radial strings and border structures has been found in these cells. The features have been revealed by visualization of ribonucleoproteides and lipoproteins. The same process takes place in human lymphocytes after 6-24 h of 3-phosphoglyceric aldehyde stimulation in vitro. A comparative study of morphologic peculiarities of hemopoietic cell nucleolar apparatus depending on cell cycle phase has been performed. The action of cytostatics upon the structure of nucleus perinucleolar zone has been investigated.

Antineoplastic Agents↗

PubMed1988

[Comparative study of the somatic conjugation of chromosomes in the neural ganglia of male and female Drosophila melanogaster D-32].

The frequency of somatic conjugation of the 2nd and 3d chromosome pairs has been analysed in male and female neural ganglia from Drosophila melanogaster larvae D-32 line. The frequency of conjugation found for males was 1.5 times lower than for females. On this basis a supposition concerning less duration of homologous conjugation in males has been put forward. It is suggested that it is due to the differences in space arrangement of homologous chromosomes holding their conjugation.

Animals↗

PubMed1986

[Demonstration and characteristics of the perinucleolar zone of the nucleus--a new morphological criterion of the nucleolar test system].

A dynamic structure of interphase nucleus--perinucleolar zone has been detected and studied in cell systems on high-level transcription and proliferation activity by means of light and fluorescent microscopy methods. A new light-microscopic level classification of nucleoli taking into account the structure of this zone is introduced. The percentage of nucleoli type distribution may be used as criterion of tissue synthesis activity. An introduction of a new morphological criterion in classical Smetana nucleolar test is under discussion.

Cell Nucleolus↗

PubMed1980