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Biomedical subjects

M A Pogrel

Publications and source records attributed to M A Pogrel.

At least 73 records · Page 4Linked to original sources

A study of infrared thermographic assessment of liquid nitrogen cryotherapy.

OBJECTIVE: To assess whether infrared thermography can accurately predict the area of soft tissue necrosis that results from liquid nitrogen cryoprobe therapy. STUDY DESIGN: Eight rats received cryosurgery on the shaved abdomen with a liquid nitrogen cryoprobe in a triple-freeze technique. The therapy was monitored with infrared thermography and thermocouple probes. The temperature reached was correlated with the area of tissue necrosis found on histologic examination at sacrifice 1 week after the cryotreatment. A parallel study was carried out on pieces on beefsteak to assess the depth and shape of freeze. RESULTS: The -20 degrees C isotherm, which is felt to correspond to the cell lethal zone, occupied the inner 70% of the area of the iceball produced. Histologically, the -20 degrees C isotherm corresponded well to the area of tissue necrosis. In depth, the iceball takes on a semicircular shape. CONCLUSIONS: Infrared tomography is expensive to use clinically and cannot be readily used in the oral cavity. However, this study does show that one can clinically estimate that the inner 70% of the area of an iceball produced by liquid nitrogen on soft tissues will ultimately undergo necrosis.

Animals↗

The assessment of trapezius muscle symptoms of patients with temporomandibular disorders by the use of liquid crystal thermography.

OBJECTIVE: To test the hypothesis that neuromuscular symptoms of patients with temporomandibular disorders that occur in the upper back and neck can be evaluated by recording the temperature patterns in the skin overlying the muscles. STUDY DESIGN: Liquid crystal contact thermography was evaluated on patients with temporomandibular disorders to demonstrate temperature changes in the muscles of the neck and upper back. The study consisted of 22 patients with temporomandibular disorders and 22 normal controls. RESULTS: The mean right-versus-left-side temperature difference of the control group was 0.13 degree C whereas the patient group showed a difference of 0.78 degree C. Of the 22 patients with temporomandibular disorders, 21 (95.5%) showed an increased temperature over the trapezius muscle on the symptomatic side. CONCLUSIONS: These findings indicate that thermography may be useful in the diagnosis of myofascial symptoms that may be associated with temporomandibular disorders.

Adult↗

Reconstruction of a complex midfacial defect with the folded fibular free flap and osseointegrated implants.

Refinements in microsurgical techniques, plate fixation, and osseointegration have changed the conceptual approach to midface reconstruction. Free tissue transfer has emerged as the ideal method of reconstructing complex midfacial defects. Single-stage bony restoration of the palate and orbital rim using the folded fibular osteocutaneous free flap is described. The fibular free flap is our first choice for reconstructing complex midfacial defects. The thin, soft, pliable tissue is ideal for intraoral and palatal reconstructions. The bone can be tailored precisely to fit any desired shape, and forms a sturdy support for both orbital and dental prostheses. With a single flap, rapid and reliable restoration of midfacial appearance, orbital support, and palatal function can be achieved.

Adult↗

Letters from California--the safety police.

I am sure many people imagine the United States of America as the land of the free, where people can do what they want unfettered by unnecessary rules, regulations and taxation. Unfortunately, the truth is very different and there are as many rules and regulations in the USA as almost anywhere else, and in some cases they are more complex since regulations come from both the federal government and the state government. Both may pass similar laws which differ in small degrees so there may be considerable areas of overlap but also considerable differences between the federal and state regulations. For dentists, a particular area of concern in recent years has been the agency known as OSHA, the Office of Safety and Health Administration.

California↗

The presence of the antilingula and its relationship to the true lingula.

20 cadaver mandibles were studied for the presence of an antilingula and its relationship to the true lingula and mandibular foramen. Three independent observers evaluated the mandibles for the presence of an antilingula. It could be identified on all 40 sides. On 9 of the sides, there was complete concordance on the position of the antilingula between the three observers. On the other 31 sides, however, there was a variation between observers of up to 11 mm. In only 43% of the cases was the antilingula within 5 mm of the true lingula. In most cases, the true lingula was postero-inferior to the antilingula. There was a negative horizontal and positive vertical correlation between the position of the antilingula on one side and its position on the contralateral side.

Aged↗

Liquid nitrogen cryosurgery and immediate bone grafting in the management of aggressive primary jaw lesions.

PURPOSE: This study evaluated whether simultaneous bone grafting will accelerate healing and reduce the complication rate of aggressive mandibular lesions treated by enucleation and liquid nitrogen cryotherapy. MATERIALS AND METHODS: Twenty patients with locally aggressive mandibular lesions were evaluated. All were treated by enucleation and liquid nitrogen cryotherapy. Ten received simultaneous bone grafting and 10 did not. Patients were matched as closely as possible for age and size of lesion. RESULTS: None of the patients who received enucleation, cryotherapy, and simultaneous bone grafting developed complications. Of the 10 patients having enucleation, cryotherapy, and no bone grafting, two patients developed pathologic fractures and one developed a wound dehiscence that healed on conservative management. Residual alveolar bone height was 81% of the preoperative level in the grafted group and 78% of the preoperative level in the nongrafted group. Additionally, 15 osseointegrated implants were placed in the group receiving bone grafting whereas none was placed in the group that was not grafted. All complications occurred with lesions greater than 4.0 cm in greatest diameter. CONCLUSION: For locally aggressive lesions larger than 4.0 cm in greatest diameter, simultaneous cancellous bone grafting following enucleation and liquid nitrogen cryosurgery will decrease the risk of complications and result in greater residual bone height and a better ability to place endosseous dental implants.

Adolescent↗

The relationship of the lingual nerve to the mandibular third molar region: an anatomic study.

PURPOSE: This study evaluated the relationship of the mandibular third molar to the lingual nerve. MATERIALS AND METHODS: An anatomic dissection of the lingual nerve in the third molar region was done on 20 cadavers (40 sides). RESULTS: The position of the nerve on one side bore no statistical relationship to the position of the nerve on the opposite side. The position of the lingual nerve was variable in both the sagittal and coronal planes. In two specimens the nerve lay superior to the lingual plate and in another the superior surface of the nerve was level with the crest of the lingual plate. CONCLUSION: These findings have implications for the avoidance of lingual nerve damage during surgery in the third molar and retromolar region of the mandible.

Cadaver↗

The surgical uprighting of mandibular second molars.

The mandibular second molars can become impacted beneath the crown of the first molars and fail to erupt normally. A study of 22 cases with follow-up periods of at least 18 months shows the results obtained by surgical uprighting of these teeth. Of 22 teeth, one has been lost but none of the remaining 21 has developed infection or required root treatment, and all are in good occlusion. Six teeth give a normal response to electrical pulp testing. In most cases, with judicious bone removal, the second molar is firm and stable after uprighting and requires no splinting, but in some cases temporary stabilization is required. The bone defect normally seen mesially after uprighting reossifies both clinically and radiographically.

Adolescent↗

A comparison of single-photon emission computed tomography and planar imaging for quantitative skeletal scintigraphy of the mandibular condyle.

A prospective study was designed to compare two methods of quantifying technetium-99m methylene diphosphonate uptake in the mandibular condyle. The standard technique expresses condylar activity as a ratio of condylar uptake to a reference (often the fourth lumbar vertebra) with planar scans (lateral images of the mandible). The experimental technique quantifies condylar activity as a ratio of condyle to clivus uptake with single-photon emission computed tomography (SPECT). The results of this study indicated that the uptake ratio of condyle/clivus by SPECT scintigram was positively correlated (p = 0.039) with the planar scan technique. The SPECT technique, similar to an axial computed tomography scan, was easier to perform with better reproducibility than the standard planar technique. In addition, activity in the clivus showed less variation than activity in the fourth lumbar vertebrae. With the development of normal uptake standards in the clivus, the SPECT technique may replace the planar image technique in nongrowing patients.

Adolescent↗

Simultaneous multifocal polymorphous low-grade adenocarcinoma. Report of two cases.

The polymorphous low-grade adenocarcinoma is a recently described variant of salivary gland adenocarcinoma with a comparatively good prognosis. Polymorphous low-grade adenocarcinoma occurs most frequently in the palate with a peak incidence between 30 and 70 years of age. The female/male ratio is approximately 2:1, and the tumors exhibit slow growth with a low recurrence rate. The simultaneous occurrence of polymorphous low-grade adenocarcinoma has not been previously reported. This article reviews the existing literature and describes the first two reports of simultaneous intraoral polymorphous low-grade adenocarcinoma.

Aged↗

Transplanting teeth successfully: autografts and allografts that work.

This article suggests tooth transplantation as an alternative to other restorative options. The 10-year success rates for autografts--teeth moved from one location to another in a patient's mouth--range from 60 percent to 95 percent. Allografts, teeth moved from one person to another, are less successful. The authors report on one case of each type of transplant.

Adolescent↗

Nerve damage associated with inferior alveolar nerve blocks.

The authors reviewed 12 cases in which altered sensation occurred in the distribution of the inferior alveolar or lingual nerves following injection of a local anesthetic for restorative treatment only. Most patients suffered only partial damage, but recovery was poor. The exact mechanism of the nerve damage is unknown, but a number of theories are proposed. The extent of this problem is also unknown, but many more cases probably exist than have been reported to date.

Adult↗

Massive gingival enlargement and alveolar bone loss: report of two cases.

We present two cases of massive gingival enlargement and osteolysis of alveolar bone in a 30-year-old female and a 36-year-old male. The etiology could not be established in either case. Histologically, both lesions contained hyperplastic fibrous connective tissue and intense plasma cell infiltrates. Both patients responded well to extensive gingivectomy, extraction of all teeth, and alveoplasty.

Adult↗

The management of lesions of the jaws with liquid nitrogen cryotherapy.

The mandible and maxilla suffer from a number of lesions that, though benign, have a high recurrence rate (10 percent to 80 percent) after simple enucleation. These include the ameloblastoma, keratocyst, odontogenic myxoma, central giant cell granuloma and ossifying fibroma. The appropriate treatment of these lesions is controversial, eliciting accusations of both undertreatment and overtreatment. Liquid nitrogen cryotherapy may be a valuable treatment modality to prevent recurrences of these lesions without causing cosmetic deformity.

Adult↗