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Biomedical subjects

M A Pollock

Publications and source records attributed to M A Pollock.

6 recordsLinked to original sources
PubMed1992

Method comparison--a different approach.

The commonly accepted method of analysing data from method comparison studies is regression analysis, a method which has limitations. This study illustrates the use of a graphical presentation of data, the difference plot, which can be used as an alternative to least squares regression analysis. The data from comparison studies performed on five methods were analysed both by Deming's regression analysis, with calculation of the correlation coefficient, and by the difference plot. The results show that in most cases much more relevant information was obtained from the difference plot.

Androstenedione↗
PubMed1990

Local neurovascular island flap.

Fingertip amputation, with loss of the terminal pulp and bone exposure presents a difficult problem. Reconstruction with use of a local neurovascular island flap has been done in twenty-one patients to restore sensibility and function with preservation of length. All patients achieved two-point discrimination values within two millimeters of the normal contralateral fingertip, with adequate pad for pain-free pinch. We advocate this procedure for deep pulp loss over the distal phalanx. It is reliable, single-staged, and provides skin coverage closer to normal than any regional flap technique.

Adolescent↗
PubMed1989

Laboratory based study of undetectable thyroid stimulating hormone.

The clinical importance of an undetectable thyroid stimulating hormone (TSH) concentration (less than 0.2 mU/l) was studied in a consecutive series of 2573 requests for routine thyroid function tests. Two hundred and seventeen (8.4%) patients had an undetectable TSH concentration, and of these 39 (18%) had otherwise normal thyroid hormone concentrations and no history of thyroid disease. In a follow up study 71 patients (34 outpatients and 37 inpatients) with undetectable TSH concentration associated with otherwise normal thyroid hormone concentrations were randomly selected during routine reporting of thyroid function test results. None of these patients had a history of thyroid disease. Sex hormone binding globulin concentrations were increased in five out of 50 of these patients and antithyroid antibodies were detectable in four out of 49, suggesting that in most cases the isolated undetectable TSH concentration was not associated with thyroid dysfunction, particularly hyperthyroidism. Isolated undetectable TSH concentration was observed in both inpatients and outpatients and was not associated with any particular clinical condition. Repeat specimens were received in 54 of the 71 patients and TSH concentration remained persistently undetectable in 35 of these.

Autoantibodies↗
PubMed1982

Prediction of outcome in neonates using EEG.

To determine the value of EEG in predicting prognosis, the recordings of 30 neonates were re-examined using a specially devised method of visual rating which permitted quantitative assessment of 13 EEG items. Seven clinical variables were also coded. The data were submitted to computer discriminant function analysis, to determine whether the outcome could be predicted and which EEG variables contributed most effectively. Marked asymmetries, many slow transients, and a wide range of variability of suppression durations were the main indicators. The state of consciousness during the recording and the gestational age were the clinical variables which were useful. It was possible to predict outcome using this technique in 28 of the 30 patients. The same procedure was applied to serial recordings with equal value. The combination of visual ratings carried out, without reference to clinical information and requiring no subjective statement as to normality or abnormality of the features in the recording, seems to offer a contribution in the difficult field of neonatal EEG.

Electroencephalography↗