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Biomedical subjects

M A Repina

Publications and source records attributed to M A Repina.

At least 19 recordsLinked to original sources

Reducing maternal mortality in St Petersburg.

Following the entry of St Petersburg into Europe's Healthy Cities Project in 1991 it was decided that the highest priority should be given to reducing the city's maternal mortality ratio, then standing at approximately 70 deaths per 100,000 live births. Preventing deaths from unsafe, illegal abortion became the main focus of attention. The use of modern contraceptive methods was promoted, information was disseminated to improve the utilization of family planning services, special outreach services for teenagers were established, and providers were given opportunities for education and training. The maternal mortality ratio and the abortion rate have now declined and contraceptive use appears to be increasing. These achievements are attributable in large measure to the commitment of a broad spectrum of St Petersburg society as well as to outside support.

Adolescent↗

[Extracellular DNA in the blood of pregnant women].

The level of extracellular DNA increases in the blood of women during pregnancy. By means of PCR, the full-size Alu repeats were observed among extracellular blood DNA repeats of pregnant women. Furthermore, with Tc65 type primer the PCR method allowed to observe in the blood DNA fragments flanked by inverted Alu repeats (inter Alu repeats). The presence of such a type of inter Alu repeats was estimated in the blood of women being in the first trimester of pregnancy only, but was not estimated among blood DNA fragments of women of the last trimester of pregnancy. It is discussed which types of cells may serve as a source of extracellular blood DNA (either trophoblast cells, lymphocytes, or decidual cells), the significance of such DNA for pregnancy being appreciated.

Base Sequence↗

[Echomorphologic parallels in the ultrasound examination of the placenta].

Results of the ultrasound and morphological examination of the villous chorion of women with physiological pregnancy (34 cases) and with late pregnancy toxicoses (280 cases) were compared. A gradual decrease of the chorion acoustic density in physiological pregnancy correlates with a development of the compensatory-adaptive reaction (CAR) on the tissue level and serves a favourable prognosis for the pregnancy outcome. In patients with late pregnancy toxicosis, alterations of the chorion echogenicity occur at different periods of the pregnancy and reflect the CAR disturbances facilitating the development of various forms (stages) of the placenta insufficiency. The results obtained indicate possibilities of placentography use for a differential approach to the choice of methods and terms of delivery in late pregnancy toxicoses.

Adaptation, Physiological↗

[The role of examination of hemostatic system during pregnancy in prophylaxis of obstetrical hemorrhages].

The paper provides the results of a 8-year practice of the Leningrad City Obstetric and Hematological Center. The setting up of the center has ensured effective prevention of labour bleedings in the following pathological conditions of pregnants: gestosis, varicosity, anemic syndrome, and blood diseases. An algorithm has been developed for examining pregnants; recommendations are given for the management of pregnancy, labour and for the correction of hemostasiological disorders.

Anemia, Hypochromic↗

[The effect of specific trophoblastic beta 1-glycoprotein on changes in the cellular link of immunity in infected abortion].

Effects of specific trophoblastic beta-1-glycoprotein (TBG) on T- and B-cell immunity have been explored in 107 patients with purulent septic complications of abortion. TBG showed a marked suppressor effect on T lymphocytes. Persistence of TBG in blood of patients with infection complicated abortion maintains immunodeficient states. The presence of TBG in serum may increase the risk of severe septic complications of illegal abortion.

Abortion, Septic↗