PubMed Health⌕ Search

Biomedical subjects

M A Rifai

Publications and source records attributed to M A Rifai.

4 recordsLinked to original sources

[Study of sodium metabolism in the bodies of patients with essential hypertension by the profile scanning technic using 22Na].

Profile scanning with sodium-22 nuclide was performed in 37 patients with essential hypertension to determine the time-course of the isotope distribution in different parts of the body and the rate of its elimination. The rate of sodium-22 infiltration into the tissues of the pelvis and lower extremities was higher in women than in men, and that of elimination lower than in men with a stable course of arterial hypertension. This index showed no correlation with changes of the central hemodynamics and glomerular filtration. The labile and stable courses of arterial hypertension were characterized by different rates of sodium-22 uptake by the renal tissue.

Adult↗

[Changes in water-sodium balance in patients with hypertension subjected to different types of hypotensive therapy].

The parameters of water-electrolyte metabolism and central hemodynamics were studied in 44 patients with essential hypertension (stage II-III) after 3-week treatment with sympatholytics and diuretics. Patients with hyperkinetic type of hemocirculation had a sodium lack at the stage of stable hypertension, therefore the diuretic treatment is not indicated for such patients. The treatment with the diuretic oxodolin was accompanied by the decrease in the peripheral resistance of blood vessels, in sodium metabolism and its extracellular fraction, and by the increase of the deposit sodium fraction. The elevation of the renin-angiotensin system activity due to the diuretic therapy did not influence the blood pressure level and the central hemodynamics parameters.

Adult↗

Psychiatric comorbidity among hepatitis C-positive patients.

This study assessed the prevalence of psychiatric disorders among hepatitis C patients at a Veterans Affairs Medical Center. Medical records of 306 randomly selected hepatitis C-positive patients were reviewed for past and present DSM-IV-based psychiatric disorders. Each psychiatric diagnosis was independently confirmed with DSM-IV criteria using symptoms recorded in the chart. Only independently confirmed diagnoses were included for analysis. Mood disorders were present in 38% of patients; personality disorders in 30%; PTSD in 19%; other anxiety disorders in 9%; and psychotic disorders in 17%. Although alcohol use disorders were found in 86% of this patient population, intravenous drug use disorders were present in only 28%. Our data indicate that prevalence rates of a variety of psychiatric disorders are higher in veterans with hepatitis C than in the general population. Mood, anxiety, personality, and psychotic disorders were all relatively common in these patients. Psychiatric disorders may influence the course and treatment of hepatitis C infection, and psychiatrists as well as internists should be aware of the substantial psychiatric comorbidity in patients with this infection.

Adult↗