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Biomedical subjects

M A Rosa

Publications and source records attributed to M A Rosa.

At least 37 records · Page 2Linked to original sources
PubMed1981

Experimentally induced synovial sarcoma.

Synovial sarcoma has been induced in the knee joints of rats by intra-articular injection of 9-10-dimethyl-1-2-benzanthracene. Tumours developed from three to six months after the last injection. The neoplasms obtained were classified as synovial sarcoma (50%), fibrosarcoma (25%), giant cell sarcoma (15%), malignant fibrous histiocytoma (10%). The synovial membrane in the treated knee joints presented a chronic synovitis associated with fibrosis and proliferation of the lining cells. The primitive tumour spread locally infiltrating muscle and the adjacent bones. Metastases occurred most frequently to the lungs (70%) and liver (20%); lymph nodes were involved in 10%.

9,10-Dimethyl-1,2-benzanthracene↗
PubMed1981

[Broncho-alveolar lavage in uranium miners (author's transl)].

This study on workers in a uranium mine is principally concerned with the characteristics of the cells recovered by LBA. First, alveolar macrophage function was studied (including viability, phagocytic activity, capillary adherence and migratory activity). Secondly the lymphocytes were identified as T, B, and then their mitogenic responses were studied; occurring spontaneously or in response to phytohemagglutinin or purified protein derivative. Finally, the biochemical aspects were examined (including immunoglobulins, total protein, albumin, phospholipids, potassium, calcium, magnesium, complement components, anti-proteases, etc.). We conclude that there were not demonstrable changes in cellular function in either smokers or non smokers in miners subjected to the ambient radiation of a uranium mine.

Cell Migration Inhibition↗