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Biomedical subjects

M A Roth

Publications and source records attributed to M A Roth.

7 recordsLinked to original sources
PubMed2001

Affective and behavioral responses to friends who neglect their friends for dating partners: influences of gender, jealousy and perspective.

Adolescents in the ninth grade (n=75) responded to a hypothetical situation involving an individual who neglects their friend as a result of their transition to steady dating. Results indicated that 53 per cent of girls and 32 per cent of boys reported past personal exclusion by their best friend who they perceived to be preoccupied by a romantic partner. Only 21 per cent of girls and 19 per cent of boys reported that they had ignored their best friend in the past while being preoccupied by a romantic partner. There were significant differences in emotional reactions of individuals depending on their gender, level of characteristic jealousy, and the perspective taken in the jealousy triangle. Analyses of suggested behavioral responses revealed a significant difference in verbosity depending on emotional reactions, gender, and level of characteristic jealousy. In general, the strategies adolescents' recommended for handling this situation were constructive, active responses that convey a continuing commitment to the relationship.

Adolescent↗
PubMed1998

Wartime stressors and health outcomes: women in the Persian Gulf War.

This descriptive correlational study of war time stressors and stress responses of women from the Persian Gulf War examined numerous stressors both physical and psychological. The psychological stressors more directly impacted postwar physical and psychological symptoms than did physical stressors. These findings add to our understanding of women's reactions to wartime stress and the types of stressors affecting women. The study provides more data to support the contention that sexual harassment is widely prevalent in the military. The study did not find data to support concerns about maternal guilt on leaving children, nor any significant evidence of stress symptomology from this situation. The results of this study confirmed the call by Wolfe, Brown, Furey, and Levin (1993) for more precise evaluation of wartime stressors in view of the changing gender composition of military forces and the subsequent increase of women in combat roles. Clinicians should be alerted to recognize gender-specific experiences. Education of military women about stressors and coping mechanisms should be broadened to address the development issue of intimacy versus isolation. Nurses, both military and civilian, must understand the effect of isolation and discrimination on women both in combat and in other high stress situations. The need for continued study of the problem of sexual harassment is confirmed. Understanding the scope of the problem and the health care outcomes strengthens the role of prevention and intervention for nurses and their clients.

Factor Analysis, Statistical↗
PubMed1993

Children's perceptions of responsibility: attitudes while working with peers with disabilities.

The purpose of this study was to examine whether participation in a community-based cooperative learning program affected attitudes toward responsibility of 13 talented and gifted students toward 49 peers with disabilities. A survey was administered to measure role perception of these students as they interacted in gross motor recreational activities with students with disabilities. There was a significant difference between pre- and posttest scores on three of six attitude items. Ordinal data suggested the gifted subjects showed an increase in their felt responsibility in this cooperative learning.

Child↗
PubMedDate not supplied

Therapy for pancreatic cancer with a recombinant humanized anti-HER2 antibody (herceptin).

The HER2/neu oncogene is overexpressed in human pancreatic cancer, but the clinical significance of that overexpression is uncertain. In the present study we investigated the antitumor efficacy of Herceptin, a new recombinant humanized anti-HER2/neu antibody, which exhibits cytostatic activity on breast and prostate cancer cells that overexpress the HER2 oncogene. That antibody may retard tumor growth in certain patients with those diseases. We quantified HER2 expression in various human pancreatic cancer cell lines and studied the bioactivity of this antibody both in vitro and in vivo. Growth inhibition by Herceptin was observed in vitro in cell lines with high levels of HER2/neu expression. Cell lines with low levels of this protein did not respond significantly to the antibody. In vivo we studied two different pancreatic cancer cell lines in an orthotopic mouse model of the disease. Herceptin treatment suppressed tumor growth in the MIA PaCa-2 tumor cell line, which expressed high levels of HER2/neu. These data suggest that Herceptin treatment of patients with pancreatic cancer who express high levels of the HER2/neu oncogene may be reasonable.

Adenocarcinoma↗