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Biomedical subjects

M A Saeed

Publications and source records attributed to M A Saeed.

12 recordsLinked to original sources
PubMed1994

13beta,14beta-dihydroxy-13alpha-isopropylabietic acid, an elicitor of contact allergy.

Abietic acid isolated from colophony (W.W. grade) was selectively oxidized in the presence of KMnO4, into 13beta,14beta-dihydroxy-14alpha-isopropylabietic acid. The structure of the compound was elucidated using UV, IR, and NMR spectroscopy. Epicutaneous application of the dihydroxy acid to colophony-sensitized guinea pigs suggested the compound as an elicitor of contact allergy that had not been tested before in contact-sensitization reactions.

Abietanes↗
PubMed1991

Severe hypernatraemia in a very preterm infant.

Hypernatraemia in very low birth weight babies has been well documented and is usually attributable to excessive insensible water loss. We report a case in which, despite a peak serum sodium concentration of 204 mmol/l, the baby survived without morbidity. Treatment was simply to increase the intake of free water in Dextrose.

Adult↗
PubMed1988

A procedural distinction between elective and progressive mutism.

This paper introduces a procedural distinction between elective and progressive mutism. In elective mutism, a child elects to talk freely with intimates (e.g. family members); in progressive mutism a child does not communicate verbally with anyone (including intimates). This analysis argues that clinicians' therapeutic goals and parents' expectations of treatment outcomes for elective mutism would differ from those applied to a case of progressive mutism and that the selection of the appropriate concept (elective vs progressive) to name the type of mutism prior to intervention would enhance treatment outcomes.

Behavior Therapy↗
PubMed1987

Labeling and functional language in a case of psychological mutism.

Talking was increased in an 11-year-old girl who recently had stopped talking to anyone in any setting, despite the absence of biological factors, mental retardation, and autism. Productive labeling (correctly naming picture cards) and functional language (talking about picture cards in the absence of such pictures) were interspersed with a series of treatment packages (including verbal instructions, imitation, tokens, and praise). Interventions for productive labeling were programmed in a changing-criterion design. Interventions for functional language were programmed in an ABC design. Higher levels of productive labeling and functional language were noted with the introduction of the particular package, in comparison to baseline. The results also showed the generalization of the procedures to the shaping of functional language in the absence of picture cards.

Behavior Therapy↗
PubMed1983

Anterior interosseous nerve syndrome: unusual etiologies.

The anterior interosseous nerve is a pure motor nerve supplying the flexor pollicis longus, flexor digitorum profundus to the index and middle finger, and the pronator quadratus. A relatively uncommon neuropathy of this nerve, called the anterior interosseous syndrome (AIS), sometimes occurs. This paper reports 2 cases of AIS which developed from unusual etiologies. The first patient developed AIS after some difficulty drawing blood from the cubital vein, while the second patient developed symptoms following bypass surgery involving intravenous injection in the cubital vein. Although the diagnosis of AIS can be made clinically by noting muscle weakness in the absence of sensory deficits, electrodiagnosis is helpful for confirming diagnosis and predicting prognosis.

Blood Specimen Collection↗
PubMed1982

Compound nerve action potentials of the medial and lateral plantar nerves through the tarsal tunnel.

The purpose of this study was to determine and standardize an easy and convenient method of studying the orthodromic latencies of the medial and lateral plantar nerves for clinical purposes using conventional equipment. Forty-one able-bodied adult subjects ranging in age from 20 to 76 years were tested orthodromically to establish normal values over fixed distances. The temperatures of the feet ranged from 26C to 32C. A standard TECA bipolar surface electrode fixed in a plastic mount was placed on the posterior tibial nerve proximal to the flexor retinaculum. The medial plantar nerve was stimulated with a bipolar surface stimulator at a distance of 10, 14, and 18cm, and at the great toe. The lateral plantar nerve was stimulated at a distance of 14 and 18cm, and at the little toe. Orthodromic latencies for the medial plantar nerve for distances of 10, 14 and 18cm, and the great toe were 2.4 +/- SD 0.15msec, 3.2 +/- SD 0.26msec, 4.0 +/- SD 0.22msec, and 5.0 +/- SD 0.38msec, respectively. Lateral plantar nerve latencies for 14 and 18cm segments were 3.2 +/- SD 0.25msec and 4.0 +/- SD 0.27msec, respectively. These standard values should allow more accurate assessment of tarsal tunnel syndrome (TTS) and peripheral neuropathies because the orthodromic method involves a mixed motor and sensory nerve action potential and should be more sensitive to early changes than a pure motor nerve action potential.

Action Potentials↗
PubMed1982

Electromyographic findings in the intrinsic muscles of normal feet.

Four intrinsic muscles were studied with electromyography (EMG) in asymptomatic feet in 70 individuals to ascertain the percentage having abnormal potentials (positive sharp waves and/or fibrillation potentials). The number having positive sharp waves ranged from 6(8.6%) in the 1st dorsal interosseous to 11(15.7%) in the extensor digitorum brevis. The number showing fibrillation potentials ranged from 0 for the abductor hallucis to 4(5.7%) for the abductor digiti minimi. The authors concluded that using positive sharp waves as a diagnostic criterion in using EMG of intrinsic foot muscles in the evaluation of certain neuromuscular problems such as radiculopathy and tarsal tunnel syndrome may be misleading, but using the presence of fibrillation potentials as a criterion may be useful. Differences in the pattern of abnormalities in males and females are also discussed.

Adult↗
PubMed1981

Influence of low intensity 2,450 MHz microwave radiation upon the growth of various micro-organisms and their sensitivity towards chemical inactivation.

The non-lethal effects of 2,450 MHz radiation upon vegetative cell of P. aeruginosa and S. aureus have been assessed at low power intensities (1 joule min-1 ml-1) over a prolonged time period (16 h). Results indicated that the cell envelope was a primary target for such radiation. Growth of micro-organisms in the presence of microwaves produced minor structural changes in their cell envelopes which resulted in an alteration of preservative sensitivity. Such changes were not sufficiently great as to result in any alteration of specific growth rates during continuous microwave exposure, neither was motility nor cellular morphology affected.

Benzalkonium Compounds↗
PubMed1981

Winging of the scapula.

Common neurogenic causes of scapular winging are serratus anterior, trapezius and rhomboid palsy. Deformity is minimal in serratus anterior palsy (long thoracic nerve); winging is accentuated by forward elevation and pushing with outstretched arms. In trapezius palsy (spinal accessory nerve), the shoulder droops and winging is accentuated by arm abduction at the shoulder level. Rhomboid weakness (dorsal scapular nerve or C5 root) is best demonstrated by slowly lowering the arms from the forward elevated position.

Adult↗
PubMedDate not supplied

The tarsal tunnel syndrome.

Tarsal tunnel syndrome is relatively rare and the diagnosis may be difficult even though the etiologies for the syndrome are multiple. The symptoms are often vague but are usually burning pain and paresthesias in the toes and soles of the feet with nocturnal exacerbations. The physical examination may elicit a sensory deficit over the cutaneous distribution of the median and/or lateral plantar nerve. There may also be tenderness over the flexor retinaculum. Electrodiagnosis, especially with the addition of the orthodromic compound nerve action potential latency technique, is essential to confirm the diagnosis. The findings may be confined to the distribution of either the medial or lateral plantar nerves and, thus, both distal latencies must be determined. Surgical decompression of the tarsal tunnel has usually proven to be helpful in those patients who do not respond to conservative treatment.

Electrodiagnosis↗