PubMed Health⌕ Search

Biomedical subjects

M A Saleem

Publications and source records attributed to M A Saleem.

22 records · Page 2Linked to original sources

Ticlopidine-associated thrombotic thrombocytopenic purpura.

Thrombotic thrombocytopenic purpura is a rare complication of ticlopidine treatment. This syndrome has been reported to occur typically within the first few weeks after the initiation of therapy. The authors describe a case of a 72-year-old woman in whom thrombotic thrombocytopenic purpura developed just 2 days after starting ticlopidine therapy for a new-onset ischemic stroke. The patient responded successfully to plasmapheresis. The authors are reporting this case to emphasize the unpredictable nature of the association between the drug and the disease, which necessitates careful hematologic monitoring.

Aged↗

Hypoxemia sans hypoxemia.

Acquired methemoglobinemia usually occurs during endoscopy after exposure to a variety of drugs commonly used in critical care units and in endoscopy suites. A rapid infusion of methylene blue can result in a complete recovery of patients with a favorable prognosis. The authors describe a case of 31-year-old woman in whom methemoglobinemia developed with the use of benzocaine, and who showed complete recovery after methylene blue infusion. Hence, the availability of methylene blue in these settings is advocated.

Adult↗

Amebic perforation of the colon.

Acute necrotising colitis and perforation of the colon due to amebic infection is usually fatal. Only three patients in the present series of nine survived surgery. Preoperative diagnosis was not possible and because of an extremely friable, blotting paper like colon, this condition was only suspected at laparotomy. Examination of ulcer scrapings for the presence of Entamoeba histolytica or histopathology is confirmatory. Resection anastomosis is mandatory as less extensive local procedures or bypass surgery are not always feasible.

Adult↗