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Biomedical subjects

M A Sandler

Publications and source records attributed to M A Sandler.

59 records · Page 4Linked to original sources

Ultrasonic findings in intramural exogastric lesions.

Four cases of intramural exogastric lesions studied by ultrasound are presented. In all four patients, a large mass was identified in the left mid- and upper abdomen with a strip of solid tissue extending toward the left hemidiaphragm anteriorly, adjacent to the left lobe of the liver. This finding, best demonstrated on longitudinal scanning, suggested that the mass originated in the stomach rather than in the spleen or splenic flexure of the colon, which are posterior in location. Two of the lesions were leiomyoblastomas and two leiomyosarcomas.

Aged↗

Case report: CT of a duodenal paraganglioma.

Paraganglioma is a neoplasm of neuroectodermal origin that occurs rarely in the bowel. This case report illustrates the previously undescribed CT appearance of a duodenal paraganglioma. An intensely enhancing mass in the region of the pancreatic head was found. The intense enhancement ruled out adenocarcinoma and focal pancreatitis. An islet cell tumor of the pancreas was the major differential diagnostic consideration.

Diagnosis, Differential↗

Computed tomographic evaluation of intrathoracic thyroid malignancy.

As only a few cases of intrathoracic thyroid malignancy with computed tomographic (CT) examination have been described, we reviewed the CT examinations of three patients with primary and five patients with recurrent thyroid malignancy involving the thorax. Irregular border of the thyroid mass, extension of tumor mass into mediastinal fat or chest wall, or lymphadenopathy suggested the malignant nature of the primary tumor. CT examination in recurrent disease demonstrated mediastinal, hilar and retrocrural adenopathy, compression of major vessels with collateral flow, pulmonary and bony metastases. CT was of value both in identifying the extent of disease and documenting response to treatment.

Adenocarcinoma↗

Sonographic manifestations of acute renal vein thrombosis: an experimental study.

Complete unilateral ligation of the renal vein was done in five adult mongrel dogs. An initial ultrasound examination was performed at 6 hours with serial scans every 12 hours until the animals died or were sacrificed. There were a number of sonographic findings, consisting of immediate renal enlargement, increased cortical thickness, sparsely distributed cortical echoes with increased transonance, indistinct cortico-medullary boundary, parenchymal anechoic areas due to hemorrhage and hemorrhagic infarct, compressed renal parenchyma appearing as echogenic clusters, dilated renal veins, and renal rupture. These findings corresponded to changes in the pathologic specimens and were dependent upon the duration of the venous occlusion. In patients clinically suspected to have renal vein thrombosis, the combination of the above-described sonographic findings supplemented with findings on excretory urography should be sufficient for the diagnosis of renal vein thrombosis, eliminating the need for invasive procedures.

Animals↗

Limitations of CT in evaluation of neoplasms involving chest wall.

We reviewed the CT of 20 patients with peripheral lung malignancies in which CT appearance suggested chest wall invasion on the basis of extension of mass around ribs into fat or muscle of the chest wall, or definite bone destruction. We correlated these findings with other radiographic studies and surgical and autopsy results. All 11 cases in which CT indicated chest wall involvement on the basis of definite bone destruction were confirmed. Tumor extension into the chest wall was disproven in six of the remaining nine cases in which invasion was suggested on the basis of tumor infiltration between ribs or extension of tumor into fat or soft tissue planes. Our findings confirm the lack of reliability of CT findings in determining the extension of malignancy into the chest wall, except when definite bone destruction is present.

Adenocarcinoma↗