Distraction index, part II: inflammation in nongynecologic cytology.
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Biomedical subjects
Publications and source records attributed to M A Schulte.
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This paper describes research on innovative ways to promote the practice of self-care by people with a chronic complaint. Considerable interest in the subject exists, as confirmed by interviews with patient groups and with a random sample of general practitioners, specialists and community nurses. The answers, however, reflected some uncertainty regarding how to carry out self-care effectively. The study reported here is part of a wider programme of research on the area between conventional health care and self-care, including the development of training programmes for medical professionals and lay people.
As the body's largest organ, the skin functions as the most important human communication organ, possessing communicative aspects of caring and healing of self and others. The program "Self-Care Activating Support" for psoriasis and other chronic skin disease is presented as an instrument for promoting health by dermatology nurses.
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To clarify the use of cytologic preparations, particularly those previously stained by the Papanicolaou method, for the immunocytochemical evaluation of large-cell carcinomas (LCCs), 37 cytologic preparations from cases diagnosed as LCC were examined using a battery of immunocytochemical stains for keratin, chromogranin, common leukocyte antigen (CLA) and B72.3. Thirty-two specimens were from the thoracopulmonary region (12 fine needle aspirates of the lung, 7 bronchial brushings, 5 bronchial washings, 2 sputa and 6 pleural fluids); the remaining specimens were fine needle aspirates of 3 lymph nodes, 1 vertebral body and 1 liver. Of the specimens analyzed, 30 of 37 were positive for keratin and 7 of 35 were positive for B72.3 (6 were positive for both). Only 1 of 37 was positive for CLA while none of 37 was positive for chromogranin. Six specimens showed no reaction with either keratin, B72.3 or chromogranin. These results confirm that the majority of LCCs consist of epithelial cells of either a squamous or an adenocarcinomatous type. They also show that immunocytochemistry is a useful diagnostic adjunct that can be applied to cytologic preparations previously stained by the Papanicolaou method; this is important since immunostaining is often considered after undifferentiated malignant cells are encountered in a previously stained preparation. However, a thorough understanding of some technical limitations is critical in the evaluation of the results of this technique when it is applied to cytologic specimens.