PubMed Health⌕ Search

Biomedical subjects

M A Shehata

Publications and source records attributed to M A Shehata.

14 recordsLinked to original sources

Clofazimin in the treatment of scleroma.

Scleroma is a chronic progressive granulomatous disease predominantly affecting the mucous membrane of the upper respiratory tract, endemic in temperate and tropical zone countries including Egypt. Many patients in early stages respond to medical treatment while others do not. In these patients an antileprotic agent Clofazimin (Lamprene) was tried in 76 patients and the therapeutic results are very promising, especially for the early stages of the disease.

Adult↗

Effects of white lupine in diets of growing turkeys.

In Experiment 1, dehulling white lupine (WL) improved growth and feed efficiency of male Large White turkey poults fed 40% WL during 4 to 21 days of age. In Experiment 2, WL was included proportionally with soybean meal in corn-soy diets of female turkeys from 0 to 17 wk of age. Soybean meal: WL ratios (S:WL) were 1:0 (control), 2:1, 1:1, and 6:1. At 17 wk of age hens on S:WL diets of 2:1 had body weights that were similar to those of birds fed the corn-soy control diets. Growth of hens fed S:WL diets of 6:1 was depressed (P less than .05). Growth depressions were greatest earlier in the study; older birds made compensatory gains. Feed efficiency of hens fed S:WL diets of 1:1 was poorer than that of controls during 0 to 11 wk but better than that of controls after 11 wk of age. Feed efficiency values were similar during 0 to 17 wk for hens fed control and S:WL diets of 2:1 and 1:1. Sensory evaluation of roasted light and dark meat of market birds revealed no taste differences in relation to WL level in the diet.

Animal Feed↗

The molluscicidal properties of Ambrosia maritima L. (Compositae). 2. Results from a field trial using dry plant material.

A field trial in Egypt of the plant molluscicide, Ambrosia maritima is described. Applications of 140, 70 and 35 mg/l-1 dry, whole plant were made to irrigation canals and drains in June. The treatment effect took between 1 and 5 weeks to become fully established. The reduction in the numbers of alive Biomphalaria alexandrina snails was generally more than 90% and was virtually the same at all treatment levels and in both types of watercourse. The snail population remained at a low level for at least 3 months until September-October. The possible use of a single, annual application in April or May in controlling snails throughout the main schistosomiasis transmission season in Lower Egypt is suggested.

Animals↗

The molluscicidal properties of Ambrosia maritima L. (compositae). 1. Design for a molluscicide field trial.

The composite plant, Ambrosia maritima is toxic to the snail intermediate hosts of schistosomiasis. A field trial was required to confirm this activity. A preliminary survey of irrigation canals and drains was conducted using two snail sampling methods. The results have been used to indicate the minimum number of watercourses which would have to be treated and the number of sampling stations per watercourse required to establish statistical significance in a kill of snails obtained from a molluscicide treatment.

Analysis of Variance↗

The effect of oestrogen on the nasal respiratory mucosa. An experimental histopathological and histochemical study.

An experimental histopathological and histochemical work carried out in thirty guinea-pigs of an average weight of 475 gm. receiving oestrogen in the form of ethynyl oestradiol in a dose of 10 microgram/animal/day and aiming at a study of the effects of oestrogen on the respiratory nasal mucosa. The histopathalogical lesions of the respiratory nasal mucosa were in the form of squamous metaplasia and spongiosis of the lining epithelium, with oedema of the underlying corium, glandular hyperplasia submucosal cellular infiltration, increased vascularity and some vascular changes in the form of endothelial proliferation with intimal thickening. Histochemical enzymatic alterations were in the form of increased succinic dehydrogenase activity in the epithelium as well as in the hyperplastic submucous glands, intensified reaction of the acid phosphatase in the cells of the corium, and the appearance of alkaline phosphatase activity in the apical parts of the cells lining the glands, indicating increased secretory activity. All the changes obtained in the histopathological and histochemical studies can be attributed to hormonal stimulation of the nasal mucosa.

Acid Phosphatase↗

Atrophic rhinitis.

Explore the source record for details and available documents.

Adolescent↗

Concentrations of salinomycin in eggs and tissues of laying chickens fed medicated feed for 14 days followed by withdrawal for 3 days.

Laying chickens were fed medicated feed containing various concentrations of sodium salinomycin (SAL) for 14 days followed by a 3 day withdrawal period. Eggs, collected during treatment and withdrawal, tissues and ovarian yolk of birds slaughtered after 0, 1, and 3 days' withdrawal were extracted and analysed by high performance liquid chromatography (HPLC). Tissues, ovarian yolk and freeze-dried egg albumen and yolk were extracted with acetone, followed by partitioning with petroleum ether and HPLC analysis. Albumen was extracted with methanol and analysed without further clean-up. Salinomycin was detected at 520 nm after post-column reaction with vanillin at 95 degrees C. Recoveries of fortified salinomycin from freeze-dried eggs (albumen and yolk) and tissue, premix and feed were nearly quantitative (> 90%), except liver which was < 85%. The detection limit was estimated to be 5 ng g-1, with the practical quantifiable limit being about 10 ng g-1. Highest SAL concentrations were in the more fatty components such as egg yolk, ovarian yolk and subcutaneous fat. SAL residues in other tissues were generally low and followed the order liver, kidney, thigh and breast muscles. SAL residues were dependent on the SAL concentration in feed and declined rapidly during withdrawal.

Administration, Oral↗