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Biomedical subjects

M Abdou

Publications and source records attributed to M Abdou.

5 recordsLinked to original sources
PubMed2004

[Management of thymic cysts].

OBJECTIVE: The thymic cysts are rare tumors of the neck and anterior mediastinum. The management of these patients in our institution is reported. Minimally invasive procedures are discussed. PATIENTS AND METHODS: Six patients operated in our institution within ten years, with a follow-up of 7.1 +/-3.7 years are studied retrospectively. RESULTS: There were four women and two men with an average of 39.8 +/-16.5 years. The tumor was found on chest radiograph in four asymptomatic patients, one took medical advice for laryngeal discomfort and another for dysphagia and dyspnea. The tumor was localized in the anterior mediastinum in three cases, in the cervicomediastinal site in two cases and in the cervical site in one case. CT scan was practiced in three patients with a mediastinal tumor and MR imaging in one of them. In patients with cervical or cervicomediastinal tumor, a cervical echography was practiced. All patients were operated on: three by cervicotomy, one by sternotomy, one by partial upper mini-sternotomy and one by right lateral video-assisted mini-thoracotomy. Histology confirmed benign epithelial thymic cyst. CONCLUSION: There is no specific marker of thymic cysts. Only the surgical management, leads to precise the diagnosis and to treat these tumors. No mortality, no complications or recurrences are reported. The minimally invasive surgery takes an interesting place for thoracic location, to explore and treat these benign mediastinal lesions.

Adolescent↗
PubMed2000

DNA sequence polymorphisms in two strains of Fasciola hepatica from Egypt and Europe.

A new PCR based system was used that had broad detection capability among parasites based on a conserved region of the 18 S ribosomal DNA gene. Five samples each of European and Egyptian Fasciola hepatica of bovine origin were obtained and DNA was isolated. The target of the PCR primers was a fragment of approximately 600 nucleotides in length corresponding to a region of the 18 S rRNA gene. Sequences were compared over a 107 base pair region that identified polymorphism between the strains. All five Egyptian isolates were identical. Likewise all of the European isolates had identical sequence. There were polymorphisms between the two strains and also with F. hepatica isolates from North America. Both the European and Egyptian isolates have a single base addition in the polymorphic region. In addition there is a single base substitution in the Egyptian isolates when compared to the others. This region is a small target that can be used to identify the origins of different F. hepatica isolates.

Animals↗
PubMed1999

Parasitological effects of simultaneous infections induced by Schistosoma mansoni and aflatoxin B1 in Syrian golden hamsters.

To determine the effect of S. mansoni and aflatoxin B1, 120 hamsters were divided into six groups of 20 each as follows: group I, S. mansoni only, group II, aflatoxin B1 only, group III, S. mansoni then aflatoxin B1 eight week, group IV, aflatoxin B1 then infected with S. mansoni six weeks, later, group V, aflatoxin B1 and S. mansoni simultaneously, group VI control. Loss of body, liver, and spleen weight was more prominent in groups IV and V than in other four groups. The higher mortality rate was in group III. Animals treated with aflatoxin followed by S. mansoni infection appeared to have a less deteriorating effect on the liver (group IV) than group III treated with by S. mansoni first followed by aflatoxin treatment. No morphological abnormalities were detected in the worms including testicular changes in males but a significant number of females was immature even in copula (P < 0.01) in groups III, IV, and V. The average number of S. mansoni eggs was less in groups III, IV, and V in comparison to group I. No abnormalities were detected in the eggs for groups infected with S. mansoni. The diameters of granulomas around eggs, were large on an average in groups III, IV and V as compared with groups I and II.

Aflatoxin B1↗
PubMed1979

Distal splenorenal shunts (Warren's operation) B-mode and real time ultrasonographic assessment.

B mode and real time ultrasonography have been used in a trial to demonstrate the patency of distal splenorenal shunt done in Warren's operation. Thirty seven patients with portal hypertension, and bleeding oesophageal varices were the subject of this study. Using B-mode ultrasonography in 70% of cases (26 patients), the splenic, left renal vein and the site of anastomosis were demonstrated. In 8% (3 patients), both splenic and left renal veins were seen patent, but the site of anastomosis was not detected. In the remaining 22% (8 patients), neither the left renal vein nor the site of anastomosis could be demonstrated. Using the Real-time two dimensional ultrasound, 9 of the 37 patients were examined. The patency of both veins and the site of the shunt was demonstrated in 90% (8 patients).

Esophageal and Gastric Varices↗