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Biomedical subjects

M Acuña García

Publications and source records attributed to M Acuña García.

15 recordsLinked to original sources

[Total glossectomy without laryngectomy. Surgical techniques and its controversies].

UNLABELLED: Total glossectomy is the procedure for entire removal of the tongue, practice considered as one of the most mutilating possible done in head and neck surgery. Vital functions altered after tongue resection are: mastication, language and swallowing. It's controversial the role played by total laryngectomy considering the definitive split of respiratory and digestive tracts. Some AA. perform apart both ectomies pending of the suitable rehabilitation. OBJECTIVE: Report of a case of glossectomy recently operated maintaining the larynx and review the several operative steps, the complications until satisfactory swallow was achieved and perusal of literature on this controversial subject.

Aged↗

[A study of spontaneous regeneration of defected short nerve gaps in rats].

Nerve trunk gaps can be repaired with different anastomosis methods. We investigate if spontaneous regeneration can yield results similar to artificial repair, and have compared the degree of nerve regeneration in nerve defects of extratemporal facial nerve trunk in Wistar rats. The lesions measured 4 millimeters long. Three groups were studied: 0. Normal nerve (control). 1. No treatment (therapeutic abstention). 2. Autografts. The considered parameters were: clinical outcome (degree of postoperative facial function, aspect of the defectuous region, nerve conduction latency, and number of axons that managed to penetrate the defect as well as their morphometric characteristics (nerve area). Our conclusion is that in this model placement of autografts yielded significantly better results in all the parameters studied, in spite of the scant defect length. These results likewise allow us to use this model to compare repair by means of different graft types.

Animals↗

[Repair of facial nerve gaps with cryopreserved allografts in rats immunosuppressed with cyclosporin A].

UNLABELLED: The aim of this study is to assess the feasibility of peripheral nerve allografts pretreated utilizing cold storage and cyclosporin A to improve the facial nerve regeneration in Wistar rat. Three groups were designed: Normal Wistar rats. 4 millimeters nerve gaps repaired with cryopreserved nerve allografts. 4 millimeters nerve gaps repaired with cryopreserved nerve grafts and treated with cyclosporin A. At 16 weeks post-engraftment the animals were evaluated: Facial palsy grading system. Electrophysiologic latency. Axonal counting. Nervous fiber area immediately distal to the graft. The facial function of the experimental groups was similar to the control rats while the latency and morphometric parameters was poor than the normal rats. CONCLUSIONS: 1. Cryopreserved nerve allografts in facial nerve repair in rats are useful in the aquisition of a facial functional nerve recovery as much in immunosuppressed animal as not. 2. Cryopreservation of nerve allografts results a good method of storage of nerve grafts. 3. Cyclosporin A immunosuppression improved not much the grading facial palsy in this model but the electrophysiologic and morphometry is significantly better.

Anastomosis, Surgical↗

[Evaluation methods of the degree of regeneration after experimental nerve repair. Evaluation model for the facial nerve in rats].

The AA. after sever the facial nerve trunk of Wistar mice (so interrupting its path owing to the loss of about 4 mm of its anatomical continuity) repair the faulty portion with several grafts, and 4 months later consider the gained results achieved in each of the following parameters: functional, morphological, biochemical and electrophysiological and, finally, compare the own outcomes with bibliographic references of literature regarding this subject.

Animals↗

[Cryopreservation of neural allografts for the nerve reconstruction in experimental surgery].

The possibility of clinical employment of nervous allografts depends on the likehood of its storage and also of the need of decreasing its antigenecity. We report our methodology for cryo-preservation and storage of nervous grafts, in view of animal experimentation as well as a re-examination of other methods in order to remember grafts storages done in previous epochs.

Animals↗

[Hypoacusis and diabetes type II].

The relation between diabetes mellitus and hypoacusis is discussed since Jordao, who firstly pointed out to this association in 1854. The disparity of results according several studies are due, after other AA., to the heterogeneous of groups considered. Our study was done resorting to a patients selection and their classification in 2 homogeneous groups following different parameters: age; sex; years of course; verified angiopathic complications: peripheric vasculopathy, microalbuminuria, altered creatinine clearance; malady control: glycosylated hemoglobin. The task consisted in the study of audiometric tracings in 40 patients in order to verify statistic differences of auditive thresholds between the established groups. These courses corresponding to a sensorineural hearing loss with a deep in high tones. But no significatively worse thresholds in patients suffering other angiopathic disorders were detected.

Adult↗

[Morphological and morphometric study of sphenoidal sinus].

Thanks to the help of anatomical dissections and imaging techniques we way present this paper in which are described the morphologic characteristics of the sinus, its pneumatization types more frequently encountered, the traits more noteworthy related to the intersinusal partition and bone crests inside the sinus as well the distances detaching the sinus from the anterior wall of the sella turcica and clivus, through which wall the sinus cavity keeps in touch with noble cranial structures as the hypophysis and the brain stem. Ultimately our outcomes are compared with those given by other researchers.

Humans↗

[Chronological development of the sphenoidal sinus].

In this paper are exposed the main characteristics of the sphenoidal sinus rise, through a follow-up of its growth during the life-span of the first 20 years of life. For so doing the AA. studied the antero-posterior diameters, the vertical greatest diameter and the several distances detaching this sinus from other important anatomical references, as well the various degrees of pneumatization that the cavity may reach according as the years go over.

Adolescent↗

[Upper aerodigestive infections and their effect on sphenoidal sinus development].

Paranasal sinuses development and its ultimate mode of happening as well, has been the purpose of numerous hypotheses, that can be synthetized in this two: One which sees the pneumatization as mechanical event resulting from muscular tractions exerted on the sphenoidal sinus walls and another one supposing the pneumatization as an active phenomenon due to the osteoclastic potential of the same respiratory mucous membrane. In this work were employed 200 radiogramms belonging both to patients suffering chronic ENT infections and subjects without antecedents. The conclusion drawn out are that chronic infections do not modify the percentage of pneumatization types, but reduce the anteroposterior maximal diameter.

Adolescent↗

[Mucocele of maxillary sinus].

The term mucocele designates a cyst developing from a sinus mucosa, generally the frontal and/or ethmoidal sinuses. Maxillary sinus localization is exceptional however and raises numerous diagnostic problems in daily practice. The antral mucoceles are potentially destructive lesions, often secondary to Caldwell-Luc procedure. In this article are described in some detail the clinical, radiological and histopathological features of true antral mucoceles.

Humans↗

[Mucoepidermoid carcinoma of the larynx. A case report and review of literature].

A new case of mucoepidermoid carcinoma of the larynx is presented. The microscopic differential diagnosis of mucoepidermoid carcinoma, the several cells stem with its malignancy degrees and its repercussion on prognostic and possible treatments of this rare growth are stressed. A review of the literature is set aside.

Carcinoma, Mucoepidermoid↗

[Diabetic complications and hypoacusia].

The relationship between diabetes mellitus and hypacusia has been discussed since the work of Jordao, in 1857. Numerous authors are openly pro this viewpoint, whereas other deny it. The hypoacusis is typically bilateral, progressive and of neurosensory nature, affecting the higher frequencies. In the etiologic aspect some authors bet for an angiopathic origin, but others suppose a neuropathic cause. We have achieved a comparative study with the aim to get some conclusions that could enlighten this field. Forty patients with diabetes mellitus type II were audiometrically examinees (at threshold and with supraliminar tests) and the results compared with those of a control group. We also assessed several complications of the disease and their possible report with the auditive impairment (retinopathy and neuropathy). We found out a sensorineural, bilateral and symmetrical hearing impairment. Employing the Man Whitney's U test we compare distinct groups and explain the gained outcomes. Bibliographic review of authors defending the vascular or the nervous starting point.

Adult↗

[Sudden bilateral deafness as allergic manifestation].

The paper reports the case of a young woman who presented with a serious bilateral sudden deafness, after the ingestion of a betalactam antibiotic (known as allergic for her) in association with a mucolytic. Account of the course of the clinical events noticed, which are compared with the findings observed in other scarce publications on sudden deafness linked with allergic reactions. Finally the AA. outline a pathogenetic hypothesis in order to explain these cases of deafness involved with digestive allergic reactions.

Adult↗

[Review of epiglottitis].

Seven cases of acute epiglottitis in children (mean age 38 months) are reported. The major clinical features are described. The review of the literature on current diagnosis and treatment underlined the value of early orotracheal or nasotracheal intubation when this serious condition is suspected.

Child, Preschool↗