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M Airey

Publications and source records attributed to M Airey.

3 recordsLinked to original sources

Improvements in trauma survival in Leeds.

One hundred and eighty-six cases of major trauma (Injury Severity Score > 15) admitted to the two Leeds hospitals in 1988/89 were compared with 198 cases admitted in 1992/93 to ascertain if a system of trauma care which had evolved in the hospitals during this time had affected outcome of these patients. Injury severity score, age, and sex distribution were similar for the two groups. There were significantly fewer deaths in 1992/93, particularly in those patients with a score less than 41. It would appear that the emphasis, since 1988, on timely and definitive management of patients with major trauma has led to improved survival of the seriously injured in Leeds.

Adolescent

Enzyme transfer from pancreas to plasma during acute pancreatitis. The contribution of ascitic fluid and lymphatic drainage of the pancreas.

Acute pancreatitis was induced in anaesthetised dogs in order to investigate the relative contribution of peritoneal ascitic fluid and thoracic duct lymph as routes of transfer of pancreatic enzymes from the inflamed gland to the blood. In eight animals the exudate from the gland was collected in a plastic bag and continuously drained away, and in a further eight it was allowed to accumulate within the peritoneal cavity. The thoracic duct was cannulated and in four of the animals of each group the lymph which drained was discarded; in the other four it was returned via a venous cannula. The initial rise of plasma amylase and lipase was probably because of the direct transfer of enzyme into veins draining the pancreas or peri-pancreatic tissues. Thereafter transfer of enzyme via the thoracic duct significantly influenced plasma concentrations of amylase and lipase. The majority of enzyme released from the gland accumulated within the peritoneal ascitic fluid, but this intraperitoneal accumulation did not appear to have a significant influence upon lymph or plasma concentrations of amylase or lipase.

Acute Disease