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M Akuzawa

Publications and source records attributed to M Akuzawa.

27 records · Page 2Linked to original sources
PubMed1989

Hypothyroidism enhances carbachol-induced hypothermia in the rat.

We studied cholinergic regulation of body temperature in hypothyroid rats. Thyroidectomy caused a progressive decrease in core temperature. Intraventricular injection of carbachol in a dose of 10 nmol did not change core temperature of the normal rat, whereas the same dose of carbachol significantly decreased the temperature of thyroidectomized rats. One hundred nmol carbachol decreased to a greater extent core temperature of the thyroidectomized rats than that of normal rats. Intraventricular injection of atropine significantly increased core temperature of thyroidectomized rats. The present data indicate that brain cholinergic mechanisms participate in controlling temperature in the hypothyroid status and thyroid hormones play a significant role in the brain cholinergic regulation of body temperature.

Animals↗
PubMed1987

[TRH and cyclo (His-Pro) concentrations in the young rat brain are altered by a liquid protein diet].

Effects of liquid protein diet (LPD), that is known to be poor in protein quality, on brain TRH and cyclo (His-Pro) concentrations were explored in young male rats. At day 23 of weaning, the animals were fed either a 20% casein diet ad libitum or a 20% LPD, or were pair-fed with a 20% casein diet. They were decapitated at day 35 or day 48. The body weight of those in the LPD group decreased significantly, and the loss was sustained in comparison with those in the pair-fed and ad libitum groups. The extrahypothalamic cyclo (His-Pro) concentrations were significantly greater in the LPD group than in the pair-fed and ad libitum groups throughout the experimental period, whereas these concentrations were similar in the pair-fed and ad libitum groups. At day 48, TRH concentrations in the hypothalamus and extrahypothalamus also increased in the LPD group in comparison with the concentrations in ad libitum group. These data indicate that quality of the protein component in the diet has a potential effect on alteration in the neuropeptides, TRH and cyclo (His-Pro), in the young rat brain.

Animals↗
PubMed1980

[Blood collection from the external jugular vein in dogs (author's transl)].

The blood samples from the cephalic vein and the external jugular vein were compared hematologically and serum biochemically in 22 beagle dogs. No significant differences (p < 0.05) between these two venous blood were observed in most of the items determined except MCV (mean corpuscular volume) and serum glucose level. The time required to collect 12 ml of blood was less than 30 seconds from the external jugular vein while two to eight minutes from the cephalic vein. From the result of this study the external jugular vein is shown more suitable region for collecting much volume of blood samples than the cephalic vein in dogs.

Animals↗