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Biomedical subjects

M Alfisi

Publications and source records attributed to M Alfisi.

4 recordsLinked to original sources

Cutaneous horn.

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Female↗

A bovine muscle extract with anti-cirrhotic and anti-inflammatory properties in the rat.

An extract from bovine muscle, prepared by proteolytic digestion, inhibits the development of CC1(4)-induced liver cirrhosis when administered either subcutaneously or orally to the rat. It has a significant effect on survival time, liver and body weight, and gross and microscopic features, collagen, water, protein and triglyceride content of liver. It also accelerates the regression of CC1(4)-induced cirrhosis. Most of these effects were also achieved with a heat-stable or lipid fraction of the extract. The heat-stable fraction also shows anti-inflammatory activity in carrageenan- and egg white-induced edemas and in cotton pellet granuloma.

Animals↗

Changes in serum proteins and in major liver constituents following carbon tetrachloride and a high-fat choline-free diet in rats.

Both carbon tetrachloride and a high-fat, low-protein choline-free diet cause hepatomegaly in rats due to an accumulation of both lipids and proteins with a concomitant increase in deoxyribonucleic acid content. CCl4 causes a decline in hepatic glycogen. Serum albumin level is decreased in CCl4-treated rats and increased in those fed the experimental diet.

Animals↗