Biomedical subjects

M Alp

Publications and source records attributed to M Alp.

At least 19 recordsLinked to original sources

PubMed2006

The effect of dietary probiotic supplementation on tibial bone characteristics and strength in broilers.

A 6-wk study with 50 birds was conducted to investigate the effects of a dietary supplemental probiotic on morphometric parameters and yield stress of the tibia. Twenty-five 1-d-old broiler chicks were assigned to a control or an experimental diet containing Bacillus licheniformis and Bacillus subtilis (BioPlus 2B, CHR Hansen BioSystems, Denmark, Ugur Ecza Deposu, Turkiye Distributoru, Adapazari 41400, Turkey; each containing 2.3 x 10(8) cfu/g of spores) supplemented to the starter and finisher diets at 500 g/1000 kg of feed. Each diet was replicated 5 times with 5 birds in each replicate. Tibiotarsi weight, length, and weight/length index, robusticity index, diaphysis diameter, modulus of elasticity, yield stress parameters, and percentage Ca content were not affected by the dietary supplementation of probiotic, whereas thickness of the medial and lateral wall of the tibia, tibiotarsal index, percentage ash, and P content were significantly improved by the probiotic. Medullary canal diameter of the tibia of the birds fed the control diet was significantly greater than that of birds fed the probiotic diet. There was no treatment impact on live performance of the birds throughout the 6-wk feeding trial.

Animal Feed↗

PubMed2004

Cubital tunnel release with two limited incisions: a cadaver study.

Cubital tunnel syndrome is the second most common compressive neuropathy in the upper extremity. Treatment of cubital tunnel syndrome consists of releasing the compression on the ulnar nerve with conservative or surgical methods. Nerve decompression is an alternative simple and less invasive procedure. We have proposed a "two limited incisions" technique in order to release the cubital tunnel with two minimal incisions on a cadaveric elbow model. Thirty elbows of 15 formalin-fixed cadavers were studied. The study was performed in two steps. The first step involved a two limited incisions technique. During the second step, dissected anatomic structures were assessed. The cubital retinaculum was opened totally in 27 elbows (91%) and partially in two elbows (7%). The ulnar nerve was injured in one elbow (3%), because of the contracture of the forearm muscles. It was shown that with relaxation of the elements involved, a two limited incisions technique allowed decompression of the ulnar nerve at the elbow to be performed.

Adolescent↗

PubMed2002

The effects of dietary humate supplementation on broiler growth and carcass yield.

The growth-promoting effect of Farmagülatör DRY Humate (FH) on live performance, carcass weight, and the abdominal fat pad of broilers was studied during different feeding periods. Four hundred, 1-d-old straight-run birds were randomly distributed to 20 floor pens of an environmentally controlled house. Four dietary regimens were replicated in five pens, each containing 20 chicks, as follows: 1) birds received no added FH in the starter or grower (NAFH), 2) birds received FH from 0 to 21 d (FH0-21), 3) birds received FH from 22 to 42 d (FH22-42), 4) birds received FH from 0 to 42 d (FH0-42) in the starter and grower diets, respectively. The FH was added to the diets at 2.5 kg/per ton of feed. Starter and grower diets were formulated to meet the minimum NRC requirements for broilers and were provided as a mash feed. Body weights at 21 d were not affected by the dietary regimens. At 42 d, body weights and feed conversions of broilers were significantly affected by the dietary humate treatments. Birds fed FH22-42 weighed more than the NAFH, whereas the FH0-21 and FH0-42 were intermediate and not different from the other treatments. Feed:gain was lower for the FH22-42 and FH0-42 treatments compared to the NAFH. There was no difference in carcass yield or abdominal fat pad percentages due to feeding FH. Feeding FH during the grower period had the most beneficial effect in terms of growth and feed conversion on broiler performance.

Adipose Tissue↗

PubMed2001

Primary sternal tuberculosis: a rare unhealed case treated by resection and local rotational flap.

Primary sternal tuberculosis is very rare. Only few cases have been reported in the English-language literature. We present a case of primary sternal tuberculosis that had intractable drainage for 18 months. Diagnosis was confirmed with biopsy, and there were no other tuberculous foci. No improvement was achieved in the status of the wound despite 4 months of chemotherapy. We applied the principles as in bacterial osteomyelitis of sternum, resected the wound and covered it with a pectoralis major musculocutaneous rotational flap. The wound healed, and there was no recurrence 24 months after surgery.

Debridement↗

PubMed2000

Anesthetic management of heterotopic heart transplantation on beating heart.

Explore the source record for details and available documents.

Journal Article↗

PubMed1999

A human heterotopic transplant on the beating heart: an interim report of a successful technique performed at Kocaeli University.

Heterotopic heart transplantation is still indicated in selected patients mainly with pulmonary vascular bed problems. Cardio-pulmonary bypass (CPB) has well known deleterious effects on the pulmonary vascular bed due to leukocyte sequestration as well as on the immune response of the patients. Also the negative effects of the cardioplegia on the native heart is another drawback of the classical heterotopic heart transplantation with the use of CPB. We want to present our new implantation technique for heterotopic heart transplantation without CPB, used successfully in our institution at the Kocaeli University on a patient with resistant pulmonary hypertension and dilated cardiomyopathy.

Heart Transplantation↗

PubMed1989

Surgical treatment of bronchiectasis: a collective review of 487 cases.

Pulmonary resection to treat bronchiectasis in a total of 487 patients between December 1976 through June 1988 is reported on. The surgical treatment consisted of pneumonectomy in 190 cases (144 left and 46 right), lobectomy in 202 cases, bilobectomy in 23 cases and lobectomy combined with segmental resection in 72 cases. The overall mortality rate was 3.5%. Patients were followed up for a period ranging between 4 months to 10 years: at the end of the study 71% of the patients were completely asymptomatic. It is concluded that though the first choice of therapy must be conservative, in those patients with bronchiectasis in whom disease progresses despite medical treatment and in those whose disease requires frequent hospitalization, continuing medical treatment is unwarranted and surgery must be the choice of therapy.

Adolescent↗

PubMed1989

Surgical treatment of hydatid cysts of the lung: report on 1055 patients.

Of 1055 patients treated surgically for pulmonary hydatid disease, most (950) had isolated lung cysts, the other 105 having both liver and lung cysts. The chest radiograph was most valuable in diagnosis; the Casoni and Weinberg tests and blood eosinophil counts were found to be diagnostically unreliable. One thousand and seventy seven primary operations were performed. Cystotomy and capitonnage were carried out in 906 patients, 40 of whom also had decortication of the pleura. Other procedures included cystotomy with wedge resection of locally damaged lung (29 patients) and cyst removal with capitonnage by Ugon's method (33) or the Perez-Fontana procedure (8) and with costal resection for osteomyelitis in two cases. More radical surgery was carried out in 99 patients for longstanding infection or severe lung destruction. Postoperative complications occurred in 37 patients (3.5%) and the 30 day mortality rate was 1.7%. It is concluded that a lung conserving surgical operation is the treatment of choice for most patients with pulmonary hydatid disease. In patients with coexisting liver cysts the thoracic transpleural approach allowed the lung and liver cysts to be removed at the same session.

Adolescent↗

PubMed1988

Surgical treatment of bilateral hydatid disease of the lung via median sternotomy: experience in 60 consecutive patients.

Sixty patients who underwent operation between 1979-1987 for bilateral pulmonary hydatid disease using median sternotomy approach are reported on. Although some authors prefer two-stage thoracotomy and operate on the side with the larger cyst first, or perform simultaneous bilateral thoracotomies, we have preferred one-stage operation via median sternotomy. There were 29 female and 31 male patients, ranging in age from 5 to 55 years (mean 26.4 +/- 6.3). A total of 173 cysts were operated in 120 lungs. The usual operative technique was cystotomy and capitonnage. Operative and postoperative courses were uneventful in all but three cases (5%). The causes of mortality in these patients were excessive hemorrhage, mediastinitis, and septic shock respectively. It is concluded that median sternotomy is a better alternative method for the treatment of bilateral hydatid disease of the lung, as the duration of hospitalisation is shorter, the approach is better tolerated by the patients than thoracotomy, and it possibly prevents a second general anesthesia.

Adolescent↗

PubMed1988

Surgical treatment of childhood pleural empyema.

From June 1977 to January 1987, 175 patients underwent surgical treatment of childhood pleural empyema. The surgical treatment consisted of tube drainage in 159 (90%) cases, decortication in 31 (17%) cases, pleuropneumonectomy in 2, lobectomy in 1, and partial thoracoplasty in one cases. There were 2 hospital deaths (14 and 26 days after admission). Late recurrences didn't occur, except in one case where a partial thoracoplasty was necessary. During the follow-up of 11 to 120 months (mean 32 months) examinations were done by chest radiographs. We believe that, children with loculated empyema can be treated successfully with antibiotics and chest tube drainage in early stage. The tube drainage is a more effective method than the other surgical procedures. Few patients require open drainage, and further surgery is rarely required.

Adolescent↗

PubMed1988

[Surgical treatment of pleural mesothelioma].

Mesothelioma which is the primary tumor of the pleura has recently been subject to many researches because of its poor prognosis and the difficulties met in radical therapy. Between 1974-1986 total 46 patients with pleural mesothelioma were treated surgically at our center. Finally it was concluded that only the cases in stage I and with epithelial malignant pleural mesothelioma should be subjected to radical surgery. The remaining patients should be treated with conservative methods.

Adult↗

PubMed1988

[Pulmonary and mediastinal bronchogenic cysts].

Bronchogenic cysts are relatively rare anomalies with a congenital origin resulting in an abnormal branching of the tracheo-bronchial tree. They either develop in the pulmonary parenchyma or in the mediastinal region. Between 1975 and 1987, 21 cases of bronchogenic cysts were operated upon. Eighteen of these cysts had a pulmonary localisation and 3 were mediastinal. Only 8 of these were diagnosed pre-operatively by bronchoscopy. The major reason for delay in diagnosis is persistent or recurrent pulmonary infection. Eight cases were treated by cystectomy, 4 by simple wedge resection, 4 by segmental resection, 3 were extirpated and 2 by lobectomy.

Adolescent↗

PubMed1987

Surgical treatment of bronchial adenomas: results of 29 cases and review of the literature.

The low-grade malignant potential of bronchial adenoma has been widely reported in the medical literature. During the past 12 years we have treated 29 patients with this disease, 18 (62%) of whom required conventional lobectomy or pneumonectomy, because most of our cases had come to our center after having inappropriate treatments in other centers and loosing time. In these cases we observed either a total obstruction of a bronchus or a destroyed parenchyma due to recurrent pulmonary infections. For this reason, the number of pulmonary resections is more important than conservative surgical procedures in our center. The other 11 cases (38%) were treated by bronchoplasty or more conservative resectional procedures. There was no recurrence and the survival rate was about 96 per cent at 5 years. We believe that, in our series, we would have mostly been able to perform conservative types of resections if we could have diagnosed the disease in its early stages.

Adenoma↗

PubMed1987

Enprostil and ranitidine: comparative efficacy and safety in patients with duodenal ulcer.

This randomised, double-blind, double-dummy, multiclinic study of duodenal ulcer healing compared the efficacy and safety of enprostil with ranitidine. The six week trial admitted 164 patients with endoscopically demonstrated duodenal ulcer. Ratings of symptoms and adverse events were collated from patients' daily diaries, and endoscopy was repeated to verify healing after four weeks and, if appropriate, after six weeks. Medication used was enprostil (35 micrograms capsule) or ranitidine hydrochloride (150 mg tablet) with matching placebos twice daily. After six weeks, 81% of patients treated with enprostil and 95% of those treated with ranitidine had healed ulcers, a statistically significant difference (p = 0.007). There were no differences between treatment groups for the number of days until the daytime ulcer pain completely ceased. Night-time ulcer pain ceased significantly earlier in the group receiving ranitidine (p = 0.019) and was less severe during the week before the last visit (p = 0.001); daytime pain for ranitidine users was also less severe (p = 0.020) during this week. Mild to moderate adverse experiences were reported by 44% of enprostil and 35% of ranitidine patients. There were no severe adverse events. In conclusion, both enprostil and ranitidine were found to be safe and effective in the treatment of duodenal ulcer. However, the ranitidine regimen used in this trial produced better results than the enprostil regimen.

Clinical Trials as Topic↗

PubMedDate not supplied