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M Altaffer

Publications and source records attributed to M Altaffer.

11 recordsLinked to original sources
PubMed1987

Measurement of six enzymes with the Kodak DTSC Module, a physician's office analyzer.

We evaluated the performance of the Kodak DTSC Module for determination of alanine aminotransferase (ALT; EC 2.6.1.2), aspartate aminotransferase (2.5.1.2), alkaline phosphatase (3.1.3.1), creatine kinase (2.7.3.2), gamma-glutamyltransferase (2.3.2.2), and lactate dehydrogenase (1.1.1.27). The DTSC is a "special chemistry" accessory for the DT60 analyzer; the same multilayer film technology as that of the Ektachem 700 is used. The overall precision, assessed over a three-month period with two serum-based quality control materials, ranged from 2.2 to 8.0%. DTSC results for patients' specimens correlated well with those by the Technicon RA-1000 analyzer. The performance of the analyzer in linearity and interference studies was satisfactory for clinical use. The DTSC is simple to operate and has no technique-dependent step; it should be useful for the physician's office laboratory.

Alanine Transaminase↗
PubMed1985

The Technicon RA-1000 evaluated for measuring sodium, potassium, chloride, and carbon dioxide.

We evaluated the Technicon RA-1000 "random-access" analyzer for the measurements of sodium, potassium, and carbon dioxide by an indirect potentiometric method (ion-selective electrode) and for chloride by a colorimetric method (mercuric thiocyanate). For various concentrations of control materials the total precision (CV) ranged from 0.9 to 1.2% for sodium, 1.1 to 1.3% for potassium, 1.0 to 1.2% for chloride, and 2.8 to 3.8% for carbon dioxide. The system demonstrated acceptable performance in linearity and carryover. Patients' results from the RA-1000 correlated well with those from the Beckman ASTRA-8. In a study on potential interferences, we found that high concentrations of salicylate and bromide significantly affected measurements of carbon dioxide and chloride, respectively. The RA-1000 requires only 30 microL of sample for all four tests and it offers a high throughout (30 specimens analyzed for the four tests in 25 min). This precise, easy-to-use, random-access analyzer requires minimal maintenance.

Autoanalysis↗
PubMed1985

Determinations of immunoglobulins G, A, and M in the Technicon RA-1000.

We evaluated the Technicon RA-1000 "Random Access" analyzer for the measurements of immunoglobulins G, A, and M in serum by turbidimetry. For various concentrations of serum pools the total CV ranged from 3.0 to 4.5% for IgG, from 3.1 to 3.2% for IgA, and from 4.8 to 5.4% for IgM. The linearity of the standard curves was good in the clinically useful ranges. Results for patients' samples correlated well with those determined with the Beckman Auto ICS (rate nephelometric method). Normal reference intervals (based on data for 200 healthy blood donors) are 7.67 to 16.87 g/L for IgG, 0.87 to 3.89 g/L for IgA, and 0.61 to 2.70 g/L for IgM. The RA-1000 requires only 8 microL for all three tests and can analyze 25 specimens for all three proteins in 37 min. Compared with other methods for immunoglobulin assays, the RA-1000 has higher throughput and offers significant savings in labor and reagent costs.

Autoanalysis↗