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Biomedical subjects

M Althoff

Publications and source records attributed to M Althoff.

9 recordsLinked to original sources
PubMed1993

[Ambulatory prevention of thrombosis with low molecular weight heparin in plaster immobilization of the lower extremity].

Plaster cast immobilisation following trauma is a major risk factor for the development of deep vein thrombosis. In our controlled, randomized and prospective study on patients with minor injuries incidence of DVT in conservatively treated out-patients with plaster cast immobilisation of the leg was 3.9% in the control group (n = 126) without prophylaxis. By s.c. self-application of LMV heparin once daily the number of DVT in the prophylaxis group (n = 115) was reduced to 0. No severe side effects of NMH were observed. We conclude that thromboprophylaxis with LMW heparin once daily up to now conspiciously reduced the risk of DVT in outpatients with plaster cast immobilisation of the leg.

Adolescent↗
PubMed1989

[Concept of functional therapy exemplified by fresh closed humeral fracture].

The method of functional treatment of closed humerus fractures has gained an established position of success. A good outcome has proved to depend not only on correct indication, but it also depends decisively on physiotherapeutic exercises. The challenge to the physiotherapist has grown, and a standardised concept is now required. The authors' own approach is described in some detail. Excellent success was obtained from 80 in 82 cases, with average periods of treatment being shortened by something between two and four weeks.

Braces↗
PubMed1985

The influence of carotid body stimulation on oxygen tension and microcirculation of various organs of the cat.

To determine the importance of chemoreflex control for microcirculation, we investigated tissue pO2 and local flow on the surface of muscle, kidney, liver, and heart under systemic hypoxia and under isolated hypoxic perfusion of the carotid body in anaesthetized (pentobarbital) and artificially ventilated cats. Under systemic hypoxia, local blood flow mainly decreased in muscle and kidney, whereas liver and heart showed a flow distribution mainly with a flow decrease. Under systemic hypoxia, tissue pO2 decreased to values in the range of 0 to 10 Torr. A linear relationship was found between the pO2 change under hypoxia and the normoxic pO2 in the investigated organs, indicating local regulatory mechanisms of microcirculation. Isolated hypoxic perfusion of the carotid body caused a microflow increase in kidney in about 63%, in liver in about 55%, and in heart in all cases. Hypoxic perfusion of the carotid body caused pO2 increases in kidney and liver with mean pO2 values of 3 and 4 Torr, respectively, whereas, it produced no significant pO2 change in heart and muscle. The pO2 changes in kidney and liver significantly depended on the normoxic basic tissue pO2 level, indicating, in connection with local flow increases, a redistribution of local flow in these organs.

Animals↗