PubMed Health⌕ Search

Biomedical subjects

M Ambos

Publications and source records attributed to M Ambos.

9 recordsLinked to original sources
PubMed2000

New industrial training program for interns and postdoctoral fellows.

Pharmaceutical industry research managers consistently have difficulty finding job candidates trained to address industrial research projects. The current situation is even worse than usual because of high demand for research scientists, particularly those trained in solid phase synthesis, computational chemistry, and informatics. Network Science Corp., Chemical Computing Group, and pharmaceutical research groups are creating a website to assist students in gaining experience as industrial interns or postdoctoral fellows.

Drug Industry↗
PubMed1982

Iatrogenic intussusception: a complication of long intestinal tubes.

Intussusception secondary to long intestinal tubes is a relatively uncommon but potentially fatal occurrence. From 1976 to 1979 we have studied five patients with this complication. The mercury-filled bag stimulates peristalsis, the tube is drawn forward, and there is resultant telescoping and "pleating" of the proximal small bowel. If these pleats become fixed by adhesions, they may act as a lead point for intussusception, even after tube withdrawal. Early diagnosis is essential for effective therapy.

Adult↗
PubMed1980

Hemoductal pancreatitis.

A case of gastrointestinal hemorrhage from a splenic artery pseudoaneurysm secondary to chronic pancreatitis with bleeding into the pancreatic duct is reported. This rare phenomenon known as hemoductal pancreatitis represents a diagnostic dilemma since bleeding is intermittent and the source of hemorrhage may not be appreciated at either angiography or surgery.

Aged↗
PubMed1979

Gastrointestinal bleeding in aortic stenosis.

Gastrointestinal bleeding in aortic stenosis is an uncommon condition but when present it is often undiagnosed. The usual radiological proceedures fail to demonstrate the source of bleeding. Mesenteric angiography, however, will identify the lesion. The lesion is usually a vascular malformation located in the right colon. The angiodysplasia may also occur in other parts of the gastrointestinal tract. We have encountered five patients with aortic stenosis who had multiple massive hemorrhages of the lower gastrointestinal tract who defied diagnosis by the conventional methods. Mesenteric angiography, however, disclosed the orgin of the bleeding. In four patients vascular malformations were found in the right colon and one in the jejunum. Right hemicolectomy and partial jejunectomy resulted in a cure in all.

Aged↗
PubMed1977

Osteitis deformans of the hip joint.

It is estimated that 66% of patients with Paget's disease have involvement of the pelvis and 46% of the proximal femur. Therefore, it is not unexpected that hip pain is one of the major presenting complaints. Analysis of the radiographs of 25 hips with one or more articular sufaces involved by Paget's disease demonstrated narrowing in 24. Unlike the findings in primary degenerative joint disease, the majority of cases had a radiographic pattern characterized by uniform narrowing of the articular cartilage and minimal hypertrophic changes. Pathologic correlation was obtained from specimens of four patients who underwent total hip replacements. The pathogenesis of arthritic changes associated with osteitis deformans is not established. The evidence presented suggest that cartilagenous narrowing results from a disturbance in endochondral bone formation related to the hyperemia of Paget's disease. Secondary deformities of bone produce further derangement of joint mechanics. The secondary degenerative changes which ensue differ mechanically, and therefore radiographically, from primary degenerative joint disease.

Acetabulum↗