Biomedical subjects

M Ampil

Publications and source records attributed to M Ampil.

3 recordsLinked to original sources

PubMed1981

The importance of dietary protein in the zinc deficiency of uremia.

The pathogenesis of zinc deficiency and its relationship to hypogeusia were studied in three chronic dialysis units in Toronto. The difference between low plasma zinc levels at two of the hospitals compared to the normal levels in the third hospital was significantly related to levels of dietary zinc intake which in turn was due to the levels of dietary protein intake. Thus one cause of zinc deficiency in chronic uremia is dietary protein deprivation. In addition, in the hospital with normal plasma levels there was a small but significant rise in plasma zinc postdialysis in contrast to the other two hospitals where there was no change. Thus slight leaching of zinc from dialysis equipment could help prevent zinc deficiency in such patients. Hypogeusia was more common in zinc-deficient patients.

Ageusia↗

PubMed1980

Dialysis hyperlipemia: response to dietary manipulations.

The effects of dietary manipulations on plasma lipid concentrations were studied over a 3 month period in 8 stable uremic patients on dialysis. Each of the 4 diets was of 3 weeks' duration, and consisted of the following periods: Control (regular diet), high carbohydrate (60% of total calories ingested), control, and a low carbohydrate diet (20% of total calories ingested). The patients' weight remained stable throughout the study. A 33% reduction in plasma triglyceride concentration was observed during the low carbohydrate period (P less than 0.05, paired analysis), and a 33% increase above control values was observed during the high carbohydrate period (P less than 0.05, paired analysis). Cholesterol concentrations did not vary and remained within normal limits throughout the study. There was no significant correlation observed between either insulin or glucagon levels and variations in triglyceride concentration. Reduction in the proportion of carbohydrate in the diet of dialysis patients, may be an effective long-term therapeutic approach to their hypertriglyceridemia.

Adult↗

PubMed1979

Initial experiences with continuous ambulatory peritoneal dialysis.

Continuous ambulatory peritoneal dialysis (CAPD) has been initiated on 51 patients: 27 females (mean age -- 43.9 years) and 24 males (mean age -- 46.4 years). This group has been observed for a total of 1420 patient weeks of treatment (27.3 patient years). Thirty-six episodes of peritonitis have been noted among 19 patients. The overall incidence was one episode per 39.4 patient weeks. Recurrent episodes of peritonitis resulted in discontinuation of CAPD in five (9.8%) of the patients. Three (5.9%) of the patients were unable to continue with CAPD because of its inability to control extracellular fluid balance. In the patients who transferred from intermittent peritoneal dialysis to CAPD, there was a 4.5 mg/dl drop in serum creatinine and a 34 mg/dl drop in mean BUN values. There was a rise of approximately 2 gm in the hemoglobin levels of this group of patients. If the problem of peritonitis can be solved, CAPD will become the dialytic treatment of choice for the majority of patients with end-stage renal disease.

Adult↗