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Biomedical subjects

M Andreassen

Publications and source records attributed to M Andreassen.

5 recordsLinked to original sources
PubMed1989

Radio-iodobenzylguanidine scintigraphy of neuroblastoma: conflicting results, when compared with standard investigations.

Seventy-one patients with neuroblastoma (NB) and 25 patients with other neoplastic or nonneoplastic diseases were studied with MIBG scintigraphy. Sensitivity and specificity at diagnosis were 94% and 88%, respectively. Of 52 patients with NB studied during follow-up, 14 had on one or several occasions conflicting results, when the findings at MIBG scintigraphy were compared to standard investigations (SI: CT scan, bone scan, x-ray, and ultrasound). The correlation of MIBG scintigraphy and SI to clinical outcome were in these 14 patients not significantly different. Adding VMA-excretion measurements did not significantly improve the predictive value of MIBG scintigraphy or SI. Patients with tumor-suspected lesions only at MIBG scintigraphy should be followed closely and the nature of the lesions should be explored through biopsy.

3-Iodobenzylguanidine↗
PubMed1976

Principles in operative treatment of residual bile duct stones.

Of sixty-five patients with residual bile duct stones 17 patients had a supraduodental choledochotomy as the only operative procedure. Of the remainder, 48 patients, a supplementary sphincteroplasty was carried out in 36, and a choledochoduodenostomy was added in 12 patients. Early postoperative results showed two deaths, while 40 patients passed an uneventful postoperative course. Following sphincteroplasty three patients had residual stones at the postoperative cholangiography. These calculi had disappeared at follow-up examination. Follow-up examination with a mean observation period of six years revealed 50 patients free of symptoms. Four patients were re-operated on because of residual stones. None of these had a sphincteroplasty. It is concluded that in the operative treatment of residual bile duct stones sphincteroplasty and choledochoduodenostomy offer valuable supplements to the supraduodenal choledochotomy.

Adult↗