Biomedical subjects

M Anjanappa

Publications and source records attributed to M Anjanappa.

2 recordsLinked to original sources

PubMed2006

Design and performance of a 24-station high throughput microbioreactor.

Two prototype 24-unit microbioreactors are presented and reviewed for their relative merits. The first used a standard 24-well plate as the template, while the second consisted of 24-discrete units. Both systems used non-invasive optical sensors to monitor pH and dissolved oxygen. The systems were used to cultivate Escherichia coli. Both designs had their merits and the results obtained are presented. In addition, dissolved oxygen control was demonstrated at the milliliter scale and 24 simultaneously monitored fermentations were successfully carried out. These results demonstrated high quality high throughput bioprocessing and provide important insights into operational parameters at small scale.

Bioreactors↗

PubMed1993

Computer-aided vascular experimentation: a new electromechanical test system.

We present a new computer-controlled, electromechanical system for performing simultaneous extension, inflation, and torsion experiments on cylindrical segments of natural and artificial blood vessels. Specimens are tested while immersed in a temperature-controlled, oxygenated, physiologic solution. Deformations are measured within a central region of the specimen using noncontacting video methods. The associated axial loads, luminal pressures, and torques are measured with standard transducers. Data are collected and stored on-line, and are used in the feedback control of experimental protocols, which are prescribed using custom interactive software. Finally, we present illustrative data obtained from canine aortas and common carotid arteries.

Animals↗