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Biomedical subjects

M Ashenhurst

Publications and source records attributed to M Ashenhurst.

5 recordsLinked to original sources

Rosai-Dorfman disease presenting as bilateral lacrimal gland enlargement.

PURPOSE: To report a patient with bilateral lacrimal gland enlargement as the initial manifestation of Rosai--Dorfman disease. METHODS: Case report. RESULTS: A 14-year-old female presented with left lacrimal gland enlargement followed by right lacrimal gland enlargement 11 weeks later. Bilateral lacrimal gland biopsies were performed, and histopathologic examination revealed the diagnosis of Rosai--Dorfman disease. CONCLUSION: Patients with Rosai--Dorfman disease may present with bilateral lacrimal gland swelling in the absence of lymphadenopathy. Rosai--Dorfman disease should be considered in the differential diagnosis of bilateral lacrimal gland enlargement.

Adolescent↗

Pyogenic granuloma following oculoplastic procedures: an imbalance in angiogenesis regulation?

BACKGROUND: Pyogenic granuloma is a vasoproliferative inflammatory response composed of granulation tissue. The pathogenesis is not entirely clear. We describe a series of patients with pyogenic granulomas occurring following common oculoplastic procedures and propose a common etiology. METHODS: Sixteen cases of pyogenic granuloma that occurred after various oculoplastic procedures from 1991 to 2000 were collected from the files of two oculoplastic surgeons. RESULTS: Pyogenic granulomas were found to occur at surgical and nonsurgical sites associated with tissue irritation or inflammation or both. INTERPRETATION: Capillaries are a predominant component of wound healing and pyogenic granulomas. The growth and development of new capillaries follows an orderly sequence of events that is highly regulated by a variety of angiogenic factors. We postulate an imbalance in angiogenesis regulation as the common pathway for pyogenic granuloma development.

Adolescent↗

Combined computed tomography and dacryocystography for complex lacrimal problems.

Two imaging modalities, computed tomography (CT) and dacryocystography (DCG), were combined to demonstrate the relationships between the lacrimal system and the surrounding soft-tissue structures. In selected cases, such as those involving severe facial trauma, midfacial tumours, significant sinus disease, or previous lacrimal, nasal or sinus surgery, this imaging technique may be useful in better evaluating the anatomy of the lacrimal system and planning a surgical approach.

Adult↗

Corneal hydrops in Terrien's marginal degeneration: an unusual complication.

Spontaneous rupture of Descemet's membrane occurred in a 76-year-old woman with a 20-year history of Terrien's marginal degeneration. This resulted in corneal hydrops characterized by a clear cystic space filled with aqueous humour that formed between the epithelium and Descemet's membrane. This case represents an unusual complication of Terrien's marginal degeneration.

Aged↗

Gold implant treatment for discomfort induced by a filtering bleb.

We present a post-trabeculectomy patient suffering from blurred vision and foreign body sensation that was not alleviated by conventional treatments. Our treatment involved placing a gold weight implant onto the anterior surface of the tarsal plate to gravity-assist closure and increase coverage of the filtering bleb.

Eyelids↗