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Biomedical subjects

M Ausejo Segura

Publications and source records attributed to M Ausejo Segura.

6 recordsLinked to original sources
PubMed1997

[An analysis of the diagnoses and prescription for chronic patients at a health center].

OBJECTIVE: To find out if there are differences between inhabitants ages 14-64 with prescription charge (group A), pensioners ages 14-64 without prescription charge (group B), and pensioners aged over 64 without prescription charge (group C), related with chronic morbidity, associated treatment and costs data. DESIGN: A crossover descriptive study (1995). SETTING: Urban primary health care centre. PATIENTS AND OTHER PARTICIPANTS: Participants are inhabitants 14 and over assigned to this health centre (12,605), included in a data bank register, patients are participants with at least a chronic diagnostic (7,007). MEASUREMENTS AND MAIN RESULTS: Participants data were transferred to a practice computer system. Three groups (above) were established according to age band and prescription charge status: group A (73.6% participants), B (8.4%), and C (18%). CONCLUSIONS: Inhabitants ages 14-64 without prescription charge were a differentiated group related with number of chronic diagnoses, number of items to chronic treatment prescribed, and annual average chronically drug costs. So they are intended for use in the future in allocation of budgets to primary health care centres.

Adolescent↗
PubMed1996

[Drug-to-drug interactions and pharmaceutical advice].

OBJECTIVE: To describe suspects of drug interactions in primary health care. DESIGN: Descriptive and transversal study during 1 month. SETTING: Urban health center, primary care, Madrid (Spain). PATIENTS AND OTHER PARTICIPANTS: Patients were treated simultaneously with more than 1 drug (145), 2 general practitioners (GP) and 1 pharmacist. INTERVENTIONS: GP registered in a sheet-form data from diagnostic and pharmacological treatments. The pharmacist checked the sheet-forms to detect drug interactions, and later assessed to the GP about it. The proposals were classified in 3 ways: no change in treatment; to modify or stop the current treatment, and to monitor plasmatic level or clinical parameters. MEASUREMENTS AND MAIN RESULTS: 333 drug interactions were detected in 145 patients. The 67.5% of interactions produced by 7 groups of drugs: theophylines, diuretics, antacids, benzodiacepines, betablockers, NSAID's and ACE's. GP accepted 74% of pharmacist's proposals (recommendations). CONCLUSIONS: Seven types of drugs were involved in the main interactions in primary care. The drug interactions increased as more drugs takes a patient in an accelerated trend. Older than 55 were the most affected. GP accepted 3/4 of the recommended pharmacist proposals.

Aged↗
PubMed1995

[Hyperglycemia in toxic oil syndrome].

OBJECTIVE: To know the prevalence of hyperglycemia in patients with Spanish toxic oil syndrome (TOS). To analyze clinical, biochemical, and pathological associated factors. To compare them with a control group. DESIGN: Case and controls study. SETTING: Primary Health Care. XI Sanitary district in Madrid. PATIENTS AND OTHER PARTICIPANTS: 734 cases with toxic oil syndrome. 1474 control subjects. MEASUREMENTS AND MAIN RESULTS: Prevalence of impaired glucose tolerance was 2.95% in TOS and 0.07% in control subjects (p < 0.001; OR, 7.55; IC, 291-19.57). Diabetes No insulin treated was 7.78% in TOS and 3.26% in controls (p < 0.001; OR 250; IC 1.62-3.87). Diabetes insulin treated was 1.99% in TOS and 0.47% in controls (p < 0.01; OR, 4.98; IC, 1.80-13.78). Prevalence of diabetes mellitus in TOS was 9.77 and 3.67% (p < 0.001; OR, 2.85; IC, 1.90-4.25) in controls. The pancreatic lesions found in the necropsies were vasculitis type TOS (4 cases) and endothelial vascular lesions (1 case). CONCLUSIONS: The prevalence of hyperglycemia in TOS reached 13%, where as in the control subjects, it was 3.8% (p < 0.001). The pancreatic lesions detected in deceased TOS patients did not coincide with those commonly described in diabetes mellitus.

Adult↗
PubMed1995

[Something more about adverse reactions to medications].

OBJECTIVE: To describe adverse drug effects (ADE) and their frequency in primary care patients. DESIGN: Descriptive and longitudinal study during 1 year (1990). SETTING: Urban Health Center. Primary Care. Madrid (Spain). PATIENTS AND OTHER PARTICIPANTS: 15,483 persons, nine general practitioner and one pharmacist. INTERVENTIONS: Doctors were invited to register any adverse drug effects they had notice in their patients. Doctors registered information and gave notice to the pharmacist about medicines, dosage and period of administration, clinical manifestations, and improving or not if drug was withdrawal. MEASUREMENTS AND MAIN RESULTS: 326 adverse drugs effects were notified, 30.9 ADE per thousand attended patients. 117 principles actives were involved, and 415 clinical manifestations were registered. The more affected patients were women (2/1). The age groups with higher ADE relative frequencies were children under one year and older people. CONCLUSIONS: The absolute frequency of medicines involved in ADE are different to relative frequencies when ADE per thousand prescription units are used. Some of the ADE notified were not referred before in the bibliography, so primary care is a good place to research on pharmacosurveillance.

Adolescent↗
PubMed1995

[Computerized record system for the analysis of diagnosis of chronic diseases and their treatment in primary health care].

OBJECTIVE: To present the design and setting up of a computerised data base for primary care. DESIGN: A descriptive crossover study. The recording lasted a year. SETTING: Gómez Acebo Health Centre in Madrid. Primary Care. PATIENTS AND OTHER PARTICIPANTS: The whole of the health centre catchment population, comprising 14,407 people, as well as 20 doctors and nurses. INTERVENTIONS: The consultations of ten doctors and ten nurses at the health centre were computerised. The computer programme, language-designed for inter-related data bases, linked four data bases (users, chronic illnesses, medicines, and the diagnosis and treatment record-sheet). The population under study comprised 14,407 people over one year, 1993. MEASUREMENTS AND MAIN RESULTS: The users file held the data of 14,407 people. 7,867 of these contained 23,993 chronic diagnoses with 12,405 treatments. The commonest diagnosis groups were: cardiovascular, psychiatry, endocrinology and articulations. The therapeutic groups with most prescriptions were C (cardiovascular), A (digestive and metabolic), N (nervous system) and R (respiratory). Daily expenditure in medicines was 634,207 pesetas. CONCLUSIONS: The main contribution of this computerised data base is to be able to analyse the associations between pathologies and their associated treatments, along with the pharmacological cost per primary care transaction, interactions and adverse side-effects.

Adolescent↗