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Biomedical subjects

M B Ali

Publications and source records attributed to M B Ali.

24 records · Page 2Linked to original sources

Absence of bacteremia during nasal septoplasty.

Episodes of staphylococcal bacteremia resulting in metastatic infection have occurred in association with nasal septoplasty, and this has suggested the possible need for antimicrobial prophylaxis. In a study designed to measure the actual frequency with which transient staphylococcal bacteremia occurs during nasal septoplasty, 50 healthy patients had blood cultures drawn immediately prior to and during the procedure. Although 46% of the 50 patients studied had their nasal mucosa colonized with Staphylococcus aureus, some of the blood cultures obtained from the 50 patients showed bacterial growth. The authors conclude that staphylococcal bacteremia during nasal septoplasty is a rare occurrence, and that antimicrobial prophylaxis is unnecessary.

Adolescent↗

Investigation of the antispasmodic potential of Hibiscus sabdariffa calyces.

Addition of an aqueous extract of Hibiscus sabdariffa calyces (2.5 ml/bath approximately 125 mg of starting crude material) inhibited the tone of various isolated muscle preparations (rabbit aortic strip, rhythmically contracting rat uterus, guinea-pig tracheal chain and rat diaphragm). Other muscles were stimulated (quiescent rat uterus and frog rectus abdominis). Intravenous injection of the extract to anaesthetized cats lowered the blood pressure in a dose-response manner. The inhibitory effects were resistant to a number of standard receptor blockers but the hypotensive influence was partially blocked by atropine and the tonic effects on rat uterus were partially reduced by hydrocortisone and indomethacin.

Animals↗

Pharmacological activities of Grewia bicolor roots.

Intraperitoneal administration of the ethanol extract of Grewia bicolor root (300 mg/kg) to rats in early pregnancy (+1-4 days) did not affect the number of conception sites, but significantly increased resorption. In late pregnancy (+19-20 days), the extract (300 mg/kg) did not affect duration of the gestation period; however, 400 mg/kg was lethal to all mother rats. The active compound, apparently a peptide, exerted a serotonin-like effect on rat uterus, rat fundus and rabbit jejunum. All these effects were abolished by methysergide. A transient serotonin-like rise in cat blood pressure was produced by the active fraction and this effect was also blocked by cyproheptadine.

Animals↗

Primary Vibrio vulnificus sepsis in Kentucky.

Vibrio vulnificus is associated with infection acquired during contact with sea water or with seafood, and is seldom suspected by physicians in noncoastal states. The ease of transportation of fresh raw seafood has facilitated this organism's capacity to produce disease in geographic areas in which it was previously unseen. We have reported a case of fatal Vibrio vulnificus sepsis acquired from ingestion of fresh oysters in the inland United States.

Animals↗

Diagnosis of subdural hemorrhage in utero. Case report.

A case is presented of subdural hemorrhage diagnosed in utero at 31 weeks of gestation by fetal ultrasonography. Following delivery, clinical examination of the infant revealed hydrops fetalis, right-sided cardiomegaly, hepatic dysfunction, and coagulopathy. Prompt resolution of these problems led to a retrospective diagnosis of premature closure of the foramen ovale as the precipitating event. The causes of previously reported cases of intrauterine cerebral hemorrhage are reviewed and compared to the present case.

Adult↗