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Biomedical subjects

M B Denckla

Publications and source records attributed to M B Denckla.

87 records · Page 5Linked to original sources

The development of left-hand superiority for discriminating braille configurations.

Discrimination of braille configurations was performed better by the left hand of right-handed sighted children over age 10, paralleling a previous study in which the names of braille letters were learned. Left-hand superiority occurred sooner in males, but they were not better at the task than females, more of whom maintained a left-hand advantage as adults. As in vision, configurations differing in orientation were more difficult to discriminate than those differing in number or displacement, but this order of difficulty was the same for both hands.

Adolescent↗

Tics following methylphenidate administration. A report of 20 cases.

Among children receiving methylphenidate hydrochloride, tics developed in 14, and in six children with pre-existing tics, the tics became worse. The clinical diagnosis in 19 cases was minimal brain dysfunction (MBD), and in one case, Gilles de la Tourette syndrome. Duration and dose of medication showed no particular pattern. In only one case did tics persist unchanged after methylphenidate treatment was discontinued. Tics related to methylphenidate administration appear to be rare (20 of 1,520 cases, or 1.3%) and may point to a specific susceptibility possibly related to personality profile (obsessive, perseverative, withdrawn).

Acute Disease↗

Paired associate learning of Morse code and Braille letter names by dyslexic and normal children.

Twenty dyslexic and twenty normal children, matched for age and sex and with the same mean I.Q. were tested on their ability to learn letter names of Braille configurations presented visually or tactually and to Morse Code signals presented aurally. The dyslexic Ss learned fewer letters in all three modalities although for both groups the visual-verbal method was easiest. The deficits were not attributable to specific modality dysfunction nor to a failure of intersensory integration. More general encoding and retrieval difficulties appear to be implicated.

Child↗