Biomedical subjects

M B Encinas Gaspar

Publications and source records attributed to M B Encinas Gaspar.

3 recordsLinked to original sources

PubMed1999

[Castleman's disease: isolated retroperitoneal mass. Report of a case].

OBJECTIVE: To describe a rare case of vascular hyaline variant of Castleman's disease presenting as a solitary mass, with special reference to the radiological findings and differential diagnosis. The literature is briefly reviewed. METHODS/RESULTS: A 48-year-old male presented with nonspecific pain in the left flank. Routine analyses were unremarkable. Sonographic and CT studies showed a well-defined, highly vascularized, 3.3 x 3.6 x 4 cm retroperitoneal mass. The risk of hemorrhage made a preoperative biopsy impracticable and the mass was removed surgically. The pathological analysis of the surgical specimen showed a localized retroperitoneal angiofollicular lymphoid hyperplasia (vascular hyaline variant). CONCLUSIONS: Castleman's disease can rarely present as a solitary retroperitoneal mass, which must be distinguished from primary retroperitoneal masses that are usually malignant. Imaging techniques are not conclusive. Definitive diagnosis is based on the postoperative pathological findings.

Castleman Disease↗

PubMed1997

[[Brucellar orchiepididymitis with abscess].

OBJECTIVE: To emphasize the need to consider Brucella infection in patients presenting with acute scrotum of a possible inflammatory etiology, in endemic areas, as in some Spanish regions. The abscess forming type, although rare, should be considered. One such case is described herein and the literature briefly reviewed. METHODS: A male patient consulted for subacute inflammation and left testicular pain. He had systemic brucellosis four months earlier that had completely remitted following specific therapy. The patient had a physical examination, analytical, blood and urine analyses, specific serological tests and testicular ultrasound evaluation. RESULTS: Physical examination disclosed left testicular pain and inflammation suggesting epididimo-orchitis. The laboratory findings were normal except for high titles against Brucella. Ultrasound disclosed diffuse enlargement of the left testis with several well-defined hypoechoic areas. The foregoing data suggested abscess forming orchitis, although a neoplasm could not be discarded. Empirical antibiotic therapy was instituted initially and specific therapy for Brucella was administered subsequently, but unilateral orchidectomy was decided because of the poor response to therapy. Histopathological analysis of the surgical specimen disclosed acute abscess forming epididimo-orchitis with multifocal chronic granulomatous involvement. CONCLUSION: Brucella epididimo-orchitis must be considered when making the differential diagnosis in acute inflammatory scrotum, particularly in endemic areas, even in the absence of suggestive clinical and/or US findings. Necrotizing orchitis is a rare form of Brucella infection which must be distinguished from necrotizing involvement arising from other pathogens (TB or Salmonella). Above all, this condition must be distinguished from a tumor.

Abscess↗

PubMedDate not supplied

[Testicular microlithiasis associated with infertility].

OBJECTIVE: A case of testicular microlithiasis that had been incidentally diagnosed by ultrasound in a patient undergoing evaluation for infertility is described and the literature briefly reviewed. METHODS: The clinical, laboratory (routine blood and urine tests, hormone studies, spermiogram) and testicular ultrasound findings in a 28-year-old male who consulted for infertility are presented. RESULTS: Serum FSH and LH were raised and testosterone fell within the lower ranges. The spermiogram revealed azoospermia. US evaluation showed bilateral small hyperechoic foci without posterior acoustic shadowing, dispersed within a normal testicular parenchyma. CONCLUSIONS: Testicular microlithiasis is a rare entity which is usually discovered incidentally during testicular ultrasound evaluation for other conditions such as infertility. The underlying condition (calcium in the seminiferous duct lumen) has a specific ultrasonographic appearance and further studies are not required to make the diagnosis. The patho-genesis and the clinical implications of microlithiasis remain unclear, therefore any associated pathology, such as tumor, infertility, systemic diseases, or chromosomal disorders, must be ruled out. Regular US follow-up is advocated.

Adult↗