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Biomedical subjects

M B Guess

Publications and source records attributed to M B Guess.

5 recordsLinked to original sources

Computer-generated diagnostic correction of anterior diastemas.

A technique for pretreatment estimation of appearance following cosmetic change to the anterior teeth by using a computer-generated image has been described. Patients should be advised that the generated projection is an estimation. As with a diagnostic set-up, a computer-generated result can only approximate final treatment. The patient must understand that the result could vary for reasons that might include (1) restorative material, (2) functional occlusal needs, (3) gingival tissue irritability, (4) artificial versus outdoor light, and (5) the angle at which the photograph was made. As technology advances, there will undoubtedly be other applications for computer graphics. The authors have successfully estimated outcomes for prosthodontic, orthodontic, and orthognathic surgical treatment. If properly used, color computer estimations can be successfully integrated in a dental office as a communication tool for the dentist, patient, and laboratory technician.

Cuspid

Hyperthermia increases aminoglycoside ototoxicity.

Similarities were noted between the nature of inner ear damage produced by loud sounds and by aminoglycoside antibiotics. Since body temperature affects cochlear function and influences the effects of noise on the ear, a similar effect was predicted for the aminoglycoside, kanamycin. By environmentally elevating the body temperatures of preweanling mice to approximately 1 degree C above that of the normal adult, kanamycin ototoxicity was increased (an average 20.4 dB threshold elevation, vs. 9.3 dB for kanamycin injected mice reared at room temperature). Hyperthermia per se had no influence on auditory thresholds. This may be of relevance to humans with fever who are treated with aminoglycoside antibiotics.

Animals