Biomedical subjects

M B Hartrick

Publications and source records attributed to M B Hartrick.

3 recordsLinked to original sources

PubMed1994

State association-sponsored program for SBB candidates.

Concern about the closure of the only Specialist in Blood Banking (SBB) School in the State of Michigan prompted the Michigan Association of Blood Banks (MABB) to develop and administer a comprehensive series of lectures to meet the needs of technologists seeking SBB certification via the experiential route. The program consisted of more than 60 1(1/2)-hour lectures covering all aspects of blood banking (genetics, coagulation, immunology, blood group serology, blood collection and administration, and transfusion medicine) except infectious disease testing and management issues. The latter were presented during two free-standing one-day seminars (for which a fee was charged for those not registered for the lecture series). Educational techniques were covered in a self-study module. Two lectures were presented one morning each week from March through December, with no presentations during July. Lecturers were local volunteer experts, and detailed learning objectives were established for each topic. Each registrant was charged a nominal fee ($100 for MABB members; $150 for nonmembers). There were 32 registrants for the lecture series, with additional registrants for the seminars. Total revenue was $5,100, and expenses amounted to approximately $2,400, mostly for faculty honoraria and catering for the two seminars. The popularity of our program reflects the need for alternatives to formal SBB schools.

Journal Article↗

PubMed1989

Alloimmunization following blood transfusion.

Although it has been 20 years since Rh immunoglobulin (Rhlg) was widely introduced in the United States, anti-D still remains as a frequent alloantibody found in hospital patients. Currently, anti-D is second in frequency only to anti-K as an alloantibody of clinical significance. Estimation of alloantibody frequencies in hospital patients reveals a gradual decline in the frequencies of anti-D and anti-CD, whereas anti-K, anti-E and anti-Jka show increases in relative and absolute frequencies. This phenomenon probably reflects the optimum use of Rhlg and more aggressive transfusion treatment of patients as indicated by the red cell use factor: (Red cell transfusions -- autologous transfusions)/admissions. Such a practice may be the result of the increasing severity of illness observed in patients admitted to hospitals. Alloimmunization due to donor white blood cells, platelets, and serum proteins also frequently follows the transfusion of homologous blood. These problems, which may pose additional risks to the transfusion recipient, are reviewed.

Blood Group Antigens↗

PubMedDate not supplied

Erb, an allele to Era, and evidence for a third allele, Er.

An antibody against a low-incidence antigen was detected in the serum of a woman whose newborn infant was found to have a positive direct antiglobulin test. The antibody failed to agglutinate 79 examples of red cells having low-incidence antigens and 16 examples of high-incidence antigen-negative red cells. The woman's serum reacted strongly with her husband's red cells in the antiglobulin test and with 5 of 6 Er(a-) cell samples from unrelated donors, suggesting that the antigen has an antithetical relationship to Era. The failure of the serum to react with one Er(a-) cell sample and with cells from the Er(a+) daughter of an Er(a-b+) mother gives evidence for a silent allele, Er. Four Er(b+) bloods were found among 605 random white donors, indicating a gene frequency for Erb of 0.0033.

Adult↗