PubMed Health⌕ Search

Biomedical subjects

M B Levene

Publications and source records attributed to M B Levene.

25 records · Page 2Linked to original sources
PubMed1976

Visual complications following irradiation for pituitary adenomas and craniopharyngiomas.

Of 55 patients with pituitary adenomas or craniopharyngiomas treated with irradiation, a retrospective study revealed that 5 sustained a visual loss compatible with radiation damage to the optic nerve. No patient who received less than 250 rads/day fractions showed such visual loss. Within the range of total dosages used in this series, total dose was not an important determinant of this complication. The time to occurrence of visual disturbance ranged from 5 to 34 months following therapy.

Adenoma↗
PubMedDate not supplied

Reversible brachial plexopathy following primary radiation therapy for breast cancer.

Reversible brachial plexopathy has occurred in very low incidence in patients with breast carcinoma treated definitively with radiation therapy. Of 565 patients treated between January 1968 and December 1979 with moderate doses of supervoltage radiation therapy (average axillary dose of 5000 rad in 5 weeks), eight patients (1.4%) developed the characteristic symptoms at a median time of 4.5 months after radiation therapy. This syndrome consists of paresthesias in all patients, with weakness and pain less commonly seen. The symptom complex differs from other previously described brachial plexus syndromes, including paralytic brachial neuritis, radiation-induced injury, and carcinoma. A possible relationship to adjuvant chemotherapy exists, though the etiology is not well-understood. The cases described demonstrate temporal clustering. Resolution is always seen.

Adult↗
PubMedDate not supplied

Primary radiation therapy in the treatment of early breast cancer.

The results of the treatment of 184 breast cancers in 176 patients are reported. Local recurrence occurred in 5% of Stage I patients and 7% of Stage II patients. Local control was significantly greater in those who received an iridium implant. By combining these data with those for Stage II breast cancer patients, local control could be shown to occur with a greater likelihood and at a lower dose when gross tumor excision preceded the radiation.

Brachytherapy↗