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Biomedical subjects

M B Marks

Publications and source records attributed to M B Marks.

At least 19 recordsLinked to original sources
PubMed1984

Respiratory tract allergy to household pet birds.

Pet birds may be as great an allergenic problem as cats and dogs. Some of the estimated 25 to 30 million pet birds in the United States may cause such allergic symptoms as nocturnal wheezy cough, asthma, rhinitis, conjunctivitis or other manifestations during a short or long period of induction. Most of the 62,000 exotic birds imported each month are members of the psittacine or parrot family. Such birds may be particularly troublesome in that they pollute the home environment by antigenic discharges from their integument.

Allergens↗
PubMed1982

Nasal polyposis-etiology and treatment.

Nasal polyposis is a recurrent disorder requiring numerous surgical polypectomies. Topical nasal steroidal inhalers such as beclomethasone dipropionate (BDP) and flunisolide nasal solution have greatly changed the therapeutic strategy for controlling polypoid formation in the nasal cavities. The judicious use of short courses of oral corticosteroids combined with oral nasal decongestants lessens the need for repeated polypectomies. Nasal douching with normal saline improves nasal ventilation.

Administration, Intranasal↗
PubMed1981

An unsuspected sign of cutaneous allergy.

An eczematous eruption in the superior retroauricular areas of the scalp and often on the posterior aspects of the pinnas may be seen in about 30% of allergic children. The eruption is not generally noticed because the overhanging hair covers the affected areas. The dermatitis is seen mainly in those children afflicted with bronchial asthma, perennial allergic rhinitis, or both. A previous history of atopic or seborrheic dermatitis is, as a rule, not elicited.

Adolescent↗
PubMed1980

Bruxism in allergic children.

A study of bruxism (tooth grinding) was conducted at the University of Miami School of Medicine, at Jackson Memorial Hospital, Miami, Florida, and at the Sleep Disorders Center, Mount Sinai MEdical Center, Miami Beach, Florida. A threefold incidence of this pernicious oral habit in allergic children was disclosed as compared to nonallergic children. Dental literature stresses psychogenic factors, occlusal maladjustments, systemic conditions, and occupational pursuits which do not pertain to most children. Allergy is rarely considered. Nocturnal bruxism may be initiated reflexly by increased negative pressures in the tympanic cavities from intermittent allergic edema of the mucosa of the Eustachian tubes. Embryologic, anatomic, and neurological relationships between the muscles of the eardrum, Eustachian tubes, and jaws have a primordial, common ancestry. Chronic middle ear disturbances may promote reflex action to the jaws by stimulating the trigeminal nuclei in the brain. Sleep studies at Mount Sinai Medical Center on allergic, bruxing children have produced some interesting but incomplete results. We are attempting to develop sophisticated devices for monitoring abnormal tubal function which may be the crux of the bruxism problem.

Acoustic Impedance Tests↗
PubMed1979

Prophylactic drugs in the management of childhood asthma.

Recurrences of explosive, severe asthma in children can often be prevented by immunotherapy and constant surveillance of environmental and dietary control. In addition, judicious and preserving use of pharmaceuticals may be employed for prophylaxis in childhood asthma. These include cromolyn sodium by inhalation, beclomethasone dipropionate aerosols, round-the-clock methylxanthines and beta 2 adrenergic bronchodilator agents. Their application is discussed.

Adolescent↗
PubMed1978

Prevalence of childhood allergy in a subtropical environment: data from Dade County, Florida.

Other prevalence studies of allergy in school children have been limited to temperate zones only. The aims of this computerized investigation were wholly focused on South Florida, located in a subtropical climate. The occurrence of allergy in relation to marked geographic variations was surveyed to evaluate the prevalence of allergy in connection with these topographic differences.

Adolescent↗
PubMed1977

Continuous measurement of respiratory resistance in asthmatic children.

In 13 children (7-13 years old) with bronchial asthma in remission, respiratory system resistance was continuously measured by the forced oscillation method at 10 Hz, using on-line digital computer analysis. Corrections were made for mouth impedance which was determined from a prior Valsalva maneuver. Functional residual capacity was also periodically determined by the body plethysmographic technique in order to allow calculation of specific respiratory system conductance (SGRS). The total observation period of 45 min consisted of quiet breathing interrupted by vital capacity maneuvers. In a single-blind design, eight children were given 0.15 mg isoproterenol sulfate from a proprietary spray delivered in the beginning of an inspiratory vital capacity maneuver while five received a placebo (freon propellent alone). A significant increase in SGrs (+53%) was observed 75 sec after isoproterenol sulfate administration. SGrs peaked after 2 min (+ 61%) and remained elevated significantly for 10 min. No significant changes occurred in the placebo group. The immediate decrease in SGrs which was observed following control vital capacity maneuvers, was prevented by isoproterenol sulfate but not by the freon propellent. Our findings suggest that although peak bronchodilation does not occur before 2 min following isoproterenol sulfate inhalation, an effect, namely prevention of bronchoconstriction induced by a deep breath, is already detectable within seconds.

Adolescent↗
PubMed1977

Long-term effects of metaproterenol in asthmatic children.

Oral metaproterenol was administered daily for 3 months to asthmatic children. The study was designed to determine whether chronic tolerance developed to this drug. Initial and final crossovers on the first 2 and the last 2 days of the investigation to a test dose of metaproterenol and placebo failed to show tolerance as indicated by improvement in lung volumes and dynamic mechanics of breathing after metaproterenol. Forced expiratory volume in 1 sec was the test most consistent in demonstrating bronchodilation; the action of metaproterenol. Forced expiratory volume in 1 sec was the test most consistent in demonstrating bronchodilation; the action of metaproterenol appeared to last at least 5 hours as measured by this test. T of distribution of ventilation, e.g., single- and multiple-breath nitrogen washout tests, were not consistently altered by metaproterenol. These tests did not appear to be sufficiently sensitive to detect improvement even when airway resistance decreased and forced expiratory volume in 1 sec increased toward the normal range.

Asthma↗
PubMed1977

Pulsus paradoxus in childhood asthma--its prognostic value.

One hundred asthmatic children were examined for pulsus paradoxus, a palpable diminution or obliteration of the peripheral pulse during inspiration, while in bronchospasm. Pulsus was measured with a sphygmomanometer and the difference in systolic pressure between inspiration and expiration was noted. Seventy-five children with mild asthma had no palpable pulsus and responded with complete subsidence of symptoms with one or two injections of aqueous epinephrine, 1-1000. Twenty-five children had palpable pulsus ranging from 10 mm to 30 mm. Five patients with pulsus between 10 and 15 mm were admitted to the hospital with status asthmaticus and pneumonia; eight other patients responded to parenteral epinephrine. Twelve children had pulsus of 20 mm or greater and all were hospitalized for uncomplicated status asthmaticus. Pulsus paradoxus may be found in acute exacerbation of childhood asthma and its degree correlates with both the severity and response to bronchodilating agents.

Adolescent↗
PubMed1977

Recognizing the allergic person.

Recognition of the allergic individual is facilitated by an awareness of certain characteristic actions and various facial lesions which may be clues to other allergic problems. A gaping expression, clearing of the throat and rubbing or mashing of the eyes and nose may indicate significant rhinitis. Dark circles and bags under the eyes, long, silky eyelashes and injected conjunctivas are other signs. Bruxism and malocclusion may also be related to an allergic diathesis.

Adolescent↗
PubMed1975

Recognizing the allergic individual.

Patients with respiratory tract allergy present certain auditory and visual signs which, when correlated with the history, aid substantially in arriving at a conclusive diagnosis. The physician should be alert to the signs that indicate allergic disease. Early recognition followed by modern allergy management will help to prevent progression of the allergic process.

Adolescent↗