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Biomedical subjects

M B Miller

Publications and source records attributed to M B Miller.

At least 19 recordsLinked to original sources
PubMed1991

[Extrasystolic activity of the myocardium in pipe-rolling workers during their work].

A total of 30 apparently healthy male pipe-rolling workers having various working conditions and no resting ESG abnormalities in cardiac arrhythmias. A continuous ECG recording was performed in all the examinees during a working day, followed by interpretation of the records separately at rest and during work and automatic calculation of heart rate per min and of the number of supraventricular and ventricular premature contractions per hour. There was a heating microclimate- and hard labour-induced increase in heart rate and the number of premature contractions, ventricular premature contractions in particular.

Adult↗
PubMed1991

[Effect of working conditions on myocardial contractility in tube-rolling mill workers].

Tetrapolar rheography, M-echocardiography and visual searching ++Doppler echocardiography were used to study the state of the myocardium in 228 practically healthy male workers engaged in different working conditions at a tube-rolling mill. Revealed were increased myocardium and myocardium contraction disorders resulting from physical over-load in combination with heating microclimate and noise. The contributors proposed approaches to the preclinical diagnosis of such changes, which could be applied to the elaboration of preventive measures.

Adolescent↗
PubMed1991

Patient profile.

Explore the source record for details and available documents.

Adult↗
PubMed1991

[Potential for early diagnosis of myocardial contractility disorders in people working under unfavorable conditions].

As many as 76 practically healthy men, workers of the pipe rolling plant, were examined at rest and during bicycle ergometry using M-echocardiography and visual-retrieval doppler-echocardiography. At rest none of the examined manifested any disorders of myocardial contractility. During bicycle ergometry, workers engaged in physical labour, both easy and of medium gravity, showed a rise of myocardial contractility as the loading was increased (at usual temperatures). In persons engaged in hard physical labour and exposed to the heating microclimate, the stroke volume, ejection fraction and Vcf calculated according to the echocardiogram rose whereas no increment of the contraction and relaxation rates was recorded, which was recognized as a sign of depletion of myocardial contractility reserves.

Adult↗
PubMed1990

Bacterial antigens and neutrophil granule proteins in middle ear effusions.

Otitis media with effusion is a significant cause of hearing loss in young children. We hypothesized that persistent bacterial antigens in middle ear effusions (MEEs) might act as chronic inflammatory stimuli causing release of neutrophil proteins. Concentrations of neutrophil lactoferrin and a 37-kd cationic bactericidal protein (CAP 37) were measured in 47 MEEs collected from 27 children at the time of tympanostomy tube placement. Antigens of Streptococcus pneumoniae were detected by latex particle agglutination and those of Haemophilus influenzae by dot-blot assay. Bacterial antigens were detectable in 24 (51%) of MEEs: S pneumoniae in 10 (21%), H influenzae in 12 (26%), and both antigens in 2 (4%). Concentrations of lactoferrin and CAP 37 in H influenzae antigen-positive MEEs were significantly higher than in either S pneumoniae antigen-positive or antigen-negative MEEs. We conclude that H influenzae antigen causes a greater middle-ear inflammatory response, as judged by neutrophil products, than does S pneumoniae antigen.

Antigens, Bacterial↗
PubMed1990

Rates of dissociation of steroid and thyroid hormones from human serum albumin.

A rapid filtration assay employing dextran-coated charcoal as acceptor particles for free hormone was used to measure rates of dissociation of steroid and thyroid hormones from human serum albumin. Modification of a previously described assay allowed measurements at 1-s intervals. Nevertheless, this still permitted only minimum estimates of the dissociation rate constants. The hormones studied were thyroxine, 3,5,3'-triiodothyronine, cortisol, corticosterone, testosterone, dihydrotestosterone, estradiol, progesterone, and aldosterone. The apparent dissociation rate constant of the thyroxine-albumin complex at 37 degrees C was 1.3 +/- 0.2 s-1 (t 1/2, 0.5 s). The apparent dissociation rate constants of the other hormone-albumin complexes at 37 degrees C generally exceeded 2 s-1 (t 1/2 less than 0.35 s). Apparent dissociation rate constants at 4 degrees C were only slightly lower. These findings indicate that steroid and thyroid hormones dissociate from albumin rapidly compared with the 1-s capillary transit times that characterize many tissues.

Aldosterone↗
PubMed1990

Schizophrenic deficit in span of apprehension.

We investigated two hypotheses about the span of apprehension task in schizophrenia: (a) schizophrenics show performance deficit on the forced-choice (FC) version but not on the full-report (FR) version, and (b) schizophrenic impairment on the FC version is greater when the display subtends a wide visual angle than when it subtends a narrow one. Schizophrenic (n = 21) and normal (n = 22) groups were tested on 3 versions of the task. A narrow-angle FC version was matched psychometrically with a wide-angle one by use of a greater number of noise letters in the narrow version. Schizophrenics reported fewer correct letters than normals on the FR version but did not differ on either the wide or the narrow FC versions. The results imply that schizophrenic deficit is not specific to the FC version and that on the FC version, visual angle is not more important than number of noise letters for demonstrating schizophrenic deficit.

Adult↗
PubMed1990

Nursing care delivery systems. A nursing administrative practice perspective.

The Nursing Administrative Practice Perspective (NAPP) is a macro, ecologic, open systems, conceptual model. This model guides the discovery, understanding, prediction, and use of key resources, structures, goals, and processes in the delivery of nursing care. NAPP encompasses and expands upon established domains of nursing, person, health, and environment as they influence nursing administration practice. A heuristic device, NAPP advances the understanding of relationships between nursing administrative practice, nursing care delivery systems, and organizations.

Environment↗
PubMed1990

[Significance of visual-scanning Doppler detection in the diagnosis of early stages of cardiac insufficiency in patients with ischemic heart disease].

A method was developed for visual monitoring myocardial structures in the mode of continuous Doppler location by using a commercial Soviet device. The method proposed measures the velocity of mobility of well-defined cardiac structures. Clinical examinations showed that myocardial contractile abnormalities could be detected earlier by visual-prospecting Doppler echocardiography than by routine Doppler location and echocardiography. The IVth standard location position is the most informative in the detection of impaired contractility. When the Doppler echocardiogram in the first additional position is analyzed, the appearance of P wave may serve as a reliable criterion for diminished myocardial contractility.

Adult↗
PubMed1988

Ventilation-perfusion scan in the acutely ill patient with unilateral hyperlucent lung.

A patient with a unilateral hyperlucent lung with acute respiratory complaints is presented. A ventilation-perfusion scan was performed to rule out pulmonary embolism. The perfusion scan ( [99mTC]MAA) showed peripheral perfusion defects in the hyperlucent lung. The ventilation study (133Xe) demonstrated peripheral ventilatory defects on the single breath image in the hyperlucent lung, the filling in of these on the equilibrium view, and diffusely delayed washout in the affected lung. These findings were suggestive of the Swyer-James syndrome and critical in excluding the numerous other causes of unilateral hyperlucent lung, which are discussed. The importance of the ventilation-perfusion study (and particularly the ventilation scan) in the patient with unilateral hyperlucent lung and acute respiratory symptoms is stressed. In addition, a discussion of the Swyer-James syndrome is included.

Aged↗
PubMed1982

Hyperthyroxinemia in patients with acute psychiatric disorders.

Thyroid function tests were measured in 645 patients admitted to an acute psychiatric disorders unit. Thirty-three percent had elevated serum thyroxine (T4), and 18 percent had an elevated free T4 index (FTI). Serum triiodothyronine (T3) was low, normal, or minimally elevated in 77 patients, with a high initial free T4 index. Twenty-two patients with an initial elevation of their free T4 index were serially followed (study group). Serum T4, free T4 index, and free T4 fell in every patient: serum T4 from 13.95 +/- 1.93 micrograms/dl (mean +/- standard deviation: SD) to 9.33 +/- 2.4 micrograms/dl (p less than 0.001); free T4 index, from 6.15 +/- 0.83 to 3.79 +/- 1.1 (p less than 0.001); free T4, from 2.43 +/- 0.65 mg/dl to 1.38 +/- 0.35 ng/dl (p less than 0.001). Serum T3 was initially normal or low, and then fell in 17 patients, and rose in five. Serial testing of thyrotropin-releasing hormone (TRH) demonstrated both flat and normal responses in patients with a variety of psychiatric diagnoses and at varying stages of thyroid disease activity.

Acute Disease↗
PubMed1976

Errors and omissions in diagnostic records on admission of patients to a nursing home.

The primary and secondary diagnoses for 100 geriatric patients consecutively admitted to a nursing home were reviewed for accuracy and omissions. Primary diagnoses were identified as the direct basis for nursing home admission. Other physical, biochemical or behavioral disorders requiring continued therapeutic care were identified as secondary diagnoses. A comparison was made of the diagnosis offered by the referring physician and the diagnosis as determined by the medical staff of the nursing home immediately after admission. In 64 percent, the secondary diagnoses were either lacking or inaccurate. The extraordinarily inadequate medical performance with respect to identifying the primary clinical and therapeutic problems of the chronically ill aged was remarkably consistent, regardless of the source of the patient's referral, whether from a general or psychiatric hospital, a private home, or another nursing home. The results of this study revealed a significant degree of unpreparedness and malaise in some members of the medical profession concerning the care of the chronically ill aged, particularly when such patients demonstrate behavioral disorders superimposed upon physical disease. Failure to identify the patient's needs through diagnosis must result in poor, inadequate or inappropriate treatment programs.

Aged↗