Peptide alkaloids from Zizyphus sativa bark.
Two new cyclopeptide alkaloids, sativanine-N and sativanine-O were isolated from the stem bark of Zizyphussativa and their structures were established by spectral analysis.
Alkaloids↗
Biomedical subjects
M B Pandey
Publications and source records attributed to M B Pandey.
A case of Hodgkin's disease presenting with recurrent laryngeal nerve palsy and tracheoesophageal fistula.
Malignancy is the most common cause of tracheoesophageal fistulas. The malignancies commonly implicated in the development of tracheoesophageal fistulas are primary bronchial or esophageal carcinomas. Hodgkins disease rarely leads to such a fistula. We report a case of Hodgkin's disease with a tracheoesophageal fistula as well as a left recurrent nerve palsy at presentation. This presentation has no precedent in literature. The patient was treated with systemic chemotherapy and involved field radiotherapy. On follow up 1 year after the completion of treatment, he was clinically and radiologically disease free.
Adult↗
Individual and combined effect of (+/-)-alpha-hydrastine and (+/-)-beta-hydrastine on spore germination of some fungi.
(+/-)-alpha-Hydrastine and (+/-)-beta-hydrastine were isolated from Corydalis longipes; both exhibited considerable efficacy against spore germination of some saprophytic and phytopathogenic fungi. While (+/-)-alpha-hydrastine was effective against most of the fungi, Helminthosporium echinoclova was least affected even at the highest dose (150 ppm). (+/-)-beta-Hydrastine was equally effective against several fungi. Mixture of both compounds was more effective than each one individually. Helminthosporium species were again the most resistant toward the mixture. The effect of both alkaloids independently on germination and development of E. pisi conidia on excised pea leaves was also shown. After pre-inoculation with (+/-)-alpha-hydrastine, the effect was more pronounced than the addition post-inoculation; maximum inhibition occurred at 200 ppm. (+/-)-beta-Hydrastine also reduced germination of conidia but was less effective than (+/-)-alpha-hydrastine. The number of primary and secondary branches of conidia and number of appressoria were not affected significantly by either compound.
Alkaloids↗
Cyclopeptide alkaloids from Zizyphus jujuba.
A new cyclopeptide alkaloid, jubanine-C (1), together with known alkaloids scutianine-C (4) and zizyphine-A (5), have been isolated from the stem bark of Zizyphus jujuba and identified by spectral analysis.
Alkaloids↗
Triterpene glycoside from Terminalia arjuna.
A new triterpene glycoside, arjunetoside, together with oleanolic and arjunic acids has been isolated from the root bark of Terminalia arjuna. The structure of arjunetoside has been established as 3-O-beta-D-glucopyranosyl-2alpha,3beta, 19alpha-trihydroxyolean-12-en-28-oic acid, 28-O-beta-D-glucopyranoside by chemical and spectral data.
Chromatography, Thin Layer↗
Eclalbatin, a triterpene saponin from Eclipta alba.
From the whole plant of Eclipta alba, a new triterpene saponin, named eclalbatin, together with alpha-amyrin, ursolic acid and oleanolic acid were isolated. The structure of eclalbatin has been established as 3-O-beta-D-glucopyranosyl-3-beta-hydroxy-olean-12-en-28-oic acid, 28-O-beta-D-arabinopyranoside (1) on the basis of chemical and spectral data.
Asteraceae↗
A simple central venous puncture detector.
During central venous cannulation, percutaneous venous puncture is performed blindly using a variety of surface landmarks on the body for different puncture sites. To avoid vessel transfixion and injury to adjacent structures, the earliest detection of venous puncture is essential. A simple central venous puncture detector is described, which not only efficiently detects entry of the needle into the vein but also prevents air embolism and blood spillage.
Catheterization, Central Venous↗
Sex-ratio and mating propensity in Drosophila biarmipes.
Mating success between purple eye colour mutant and wild type D. biarmipes was observed in Elens-Wattiaux mating chamber. Multiple-, female-, male- and no-choice techniques were used. The values of isolation estimate in different experiments are above one which provides no evidence for preferential mating between females and males of the same type. The comparison of sexual behaviour of mutant and wild flies clearly indicates that wild type males are more successful in mating than mutant males, and mutant females are more receptive than wild type females. Thus purple eye colour mutation affects mating propensity of both sexes in D. biarmipes. However, the difference in the number of matings of wild and mutant flies is highly significant in multipe- and no-choice experiments in which sex-ratio was 1:1 (equal number of males and females). But the difference is not significant when mating success was scored by female- and male-choice methods in which sex-ratio was 1:2 (one female and two males; one male:two females). Thus it is suggested that mating propensity in D. biarmipes is influenced by sex-ratio.
Animals↗
Selection for high and low pupation height in Drosophila ananassae.
Selection for high and low pupation height in Drosophila ananassae was carried out for 10 generations. Response to selection resulted in rapid divergence in pupation height in replicates of both high and low lines. There was a significant difference in mean pupation height among high, low, and control lines. Regression coefficients for both high and low lines were significantly different from zero. The realized heritability over 10 generations was 45-49 for the high lines and 26-29 for the low lines. The F1 hybrids produced by making reciprocal crosses between high and low lines showed intermediate pupation height. These findings suggest that pupation height in D. ananassae is under polygenic control, with a substantial amount of additive genetic variation.
Animals↗
Evidence for additive polygenic control of pupation height in Drosophila ananassae.
In order to study the mode of inheritance of pupation height in Drosophila ananassae, two mass culture stocks derived from ecogeographically different localities in India, were used to make a complete set of 16 crosses, which include parentals, F1, backcrosses, and F2. Pupation height defined as the distance a larva pupates over the surface of culture medium was scored in all 16 crosses. The two parental lines showed significant difference in pupation height. The F1 larvae in both reciprocal crosses had intermediate pupation height and there was no difference between two reciprocal crosses as well as between F1 and mid parent value. However, there was greater variance in the F2 generation. These findings provide evidence that the inheritance of pupation height fits a classical additive polygenic model and suggested that there is substantial amount of additive genetic variation in natural populations of D. ananassae. Furthermore, the analysis of reciprocal backcrosses shows significant maternal effect. Progeny with low pupating mothers showed lower pupation height than those with low pupating fathers and progeny with high pupating mothers had higher pupation height than those with high pupating fathers. Since the maternal effect was found only in backcrosses but not in the F1, it is suggested that this maternal effect on pupation height follows the pattern of inheritance of a transient maternal effect.
Animals↗
Effect of biotic and abiotic factors on pupation height in four species of Drosophila.
Effect of different biotic and abiotic factors such as sex, density, larval development time, moisture, temperature and light on pupation height were tested in Drosophila ananassae, D. bipectinata, D. malerkotliana and D. biarmipes which are commonly distributed in India. In the four species there are no sex differences in pupation height. Density of larvae and moisture content of food medium strongly influence pupation height. Larval development time, light and temperature also affect pupation height but there are intra- and interspecific variations in response to these factors for pupation site preference. Thus pupation site preference in these Indian species of Drosophila is influenced by various biotic and abiotic factors. The comparison of the present results with those found in other species clearly indicates that different species may vary in their response to different factors.
Animals↗
Effect of mutation on mating propensity in Drosophila biarmipes.
By using multiple-choice technique, mating success between purple eye colour mutant and wild type D. biarmipes was studied in an Elens-Wattiaux mating chamber. Red eyed (wild type) males were more successful in mating than mutant males. However, mutant females were more receptive than wild females. The results suggest that purple eye colour mutation affects mating propensity in D. biarmipes.
Animals↗
Geographic distribution of I-R and P-M systems of hybrid dysgenesis in Indian populations of Drosophila melanogaster.
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Animals↗
Recto-vesical fistula (report of an unusual case).
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Adult↗
Flavonoids from Echinops echinatus.
A new isoflavone glycoside, echinoside (7), together with 7-hydroxyisoflavone, kaempferol-4'-methylether, kaempferol-7-methylether, myrecetin-3-O-alpha-L-rhamnoside, kaempferol and kaempferol-3-O-alpha-L-rhamnoside, has been isolated from the whole plant of Echinops echinatus. The structure of echinoside has been established by chemical and spectral data. This is the first report of the occurrence of these flavonoids in E. echinatus.
Echinops Plant↗