Biomedical subjects

M B Sammour

Publications and source records attributed to M B Sammour.

6 recordsLinked to original sources

PubMed1991

An epidemiologic study of Papanicolaou smear data at Ain-Shams University hospitals.

This study is designed to find out the association between some risk factors for cancer cervix and the sensitivity and specificity of pap smear test. Data from the Cyto-Diagnostic Unit of Department of Obstetrics and Gynaecology Ain-Shams University are used. Women included in the study are those, who have had both cytology and directed biopsies irrespective of the cytology results. 757 women from 1981-1989 met that criteria and data for them are retrieved from computer files. It is found that there is association between age of women (P less than or equal to 0.05 for sensitivity and specificity), parity (P less than or equal to 0.05 for sensitivity, P greater than 0.05 for specificity), age at marriage (P less than 0.05 for sensitivity, P greater than 0.05 for specificity), and duration of marriage (p greater than 0.05 for sensitivity, P less than 0.05 for specificity), and the sensitivity and specificity of Papanicolaou smear.

Adult↗

PubMed1979

Nucleic acids and protein changes in normal and pre-eclamptic placentae.

DNA and RNA assayed in the placentae of three groups of pregnant women: normal second trimester (16-28), normal third trimester (28 weeks up to term) and in preeclampsia. The protein level in the placentae of the three groups was also assayed. The proteins, DNA and RNA all decreased after 28 weeks and up to term in normal pregnancy. In pre-eclampsia DNA and RNA showed a significant increase compared with cases of normal third trimester pregnancy. Whereas the proteins also showed an increased level, this was still less than its concentration during the second trimester of pregnancy. Protein/DNA and RNA/DNA ratios were calculated for the three groups. These ratios showed a gradual decrease during normal pregnancy from 16 weeks up to term, but with a sharper decrease in pre-eclampsia.

Adult↗

PubMed1976

Leucine aminopeptidase activity in maternal, cord blood and placenta of normal pregnancy and in pre-eclampsia.

1) Leucine aminopeptidase (LAP) was determined in maternal and fetal blood and in the placenta of mild and severe pre-eclamptic patients, then compared to the levels of normal pregnancy. 2) The enzyme activity increased significantly in severe pre-eclampsia as compared with the mild type and with normal pregnancy. 3) In mild pre-eclamptic patients LAP activity of maternal and cord blood did not increase significantly as compared with the normal cases but the placenta showed a slight decrease. 4) The enzyme level in cord blood did not increase markedly in pre-eclampsia.

Adult↗

PubMed1976

Ceruloplasmin and copper level in maternal and cord blood and in the placenta in normal pregnancy and in pre-eclampsia.

Copper and ceruloplasmin were assayed in maternal and cord blood sera and in the placenta of 10 women with normal pregnancies, in 10 patients mild and 10 with severe pre-eclampsia. Copper and ceruloplasmin levels were significantly elevated in the maternal blood of pre-eclamptic patients as compared with normal pregnant women. The placental and cord blood concentrations of copper and ceruloplasmin showed non-significant changes, which indicates that their increase in the maternal blood is not of placental origin.

Ceruloplasmin↗

PubMed1975

Serum and Placental lactic dehydrogenase and alkaline phosphatase isoenzymes in normal pregnancy and in pre-eclampsia.

LDH isoenzymes and heat-stable alkaline phosphatase were studied in the serum and placental extract of 20 cases of pre-eclampsia and 10 normal pregnancies as a control. The starch-gel electrophoretic serum and placental isoenzymogram showed that LDH4 and LDH5 were the main isoenzymes in the placenta while LDH1 and LDH2 were the main isoenzymes in the serum in pre-eclampsia. The electrophoretic serum protein pattern in pre-eclamlobulins with decreased albumin fraction, while in the placenta, the albumin fraction was increased together with a decrease in the alpha-globulins. The electrophoretic pattern of serum alkaline phosphatase showed a main band of activity at the B-globulin zone in all cases of normal pregnancy and pre-eclampsia. In the placenta, two additional bands were detected.

Alkaline Phosphatase↗

PubMed1975

Progesterone therapy in pre-eclamptic toxaemia.

Progesterone was the principal therapeutic agent used in 40 cases of pre-eclamptic toxaemia. It was also given to 10 normal pregnant women who served as a control group. A significant fall in both the systolic and diastolic blood pressures was observed in 80% of the toxaemic patients. In all cases there was a marked increase in the 24-hour urinary output with an apparent loss of weight. Serum uric acid showed a significant drop and the urea clearance values also improved. The serum sodium showed an apparent decline while the serum potassium did not show any marked variation. The serum uric acid, urea clearance, blood urea, serum sodium and serum potassium remained unchanged in the control group.

Blood Pressure↗