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Biomedical subjects

M B Sampson

Publications and source records attributed to M B Sampson.

At least 19 recordsLinked to original sources
PubMed1994

The biophysical profile as a tool for prediction of preterm delivery.

Our objective was to determine if any of the following parameters is a predictor of preterm delivery: gestational age, cervical dilatation, or biophysical profile score.Sixty-two women with certain dates, intact membranes, and preterm contractions more frequent than 300 min underwent a 30-min ultrasonographic assessment of fetal breathing movements, fetal tone, fetal movement and amniotic fluid volume, each of which was scored as 0, 1, or 2 before any tocolytics were given. The total score (0-8) was calculated and cervical dilatation was recorded. All women were subsequently placed on tocolytics. Data were analyzed using survival analysis with stepwise regression of the covariates to determine the predictive values of the total score, its individual parameters, gestational age, and cervical dilatation to the outcome variable of hours to delivery. Gestational age, cervical dilatation and time interval to delivery were categorized and entered into a logistic regression model with the total score and its components to determine predictive odds.Total score (p < 0.0001) and cervical dilatation (p < 0.0001) were the most significant variables associated with time interval to delivery, followed by gestational age (p = 0.035). When the individual biophysical parameters were entered into the model, fetal tone (p < 0.0001), cervical dilatation (p < 0.0001) and gestational age (p < 0.014) were the only variables related to time interval to delivery. Predictive odds of delivery in less than 48 h in relation to fetal tone and cervical dilatation were calculated. Total score, fetal tone, and cervical dilatation were strongly associated with time interval to delivery. Our study did not support fetal breathing movements as a predictor of preterm delivery.

Journal Article↗
PubMed1985

Single ultrasonic estimation of fetal weight in utero compared with birth weight.

A single ultrasonic determination of fetal weight in utero was made in 270 singleton pregnancies. Infants were divided by birth weights into two groups, less than and greater than the 50th percentile. Ultrasonically determined fetal weight correlated with birth weight (R2 greater than or equal to 0.52) beyond 33 weeks' gestation. Mean fetal weights measured by ultrasound at various stages of gestation correlated well with published values.

Birth Weight↗
PubMed1985

Gonococcal endocarditis during pregnancy: simultaneous cesarean section and aortic valve surgery.

Gonococcal endocarditis is a rare and potentially fatal consequence of disseminated gonococcal infection. Presented is the first known case of culture-proved gonococcal and serratia endocarditis in pregnancy. The case was further complicated by fetal distress at 30 weeks' gestation as a result of maternal decompensation from worsening congestive heart failure secondary to rapid destruction of her aortic valve. Consequently, cardiopulmonary bypass with subsequent aortic valve replacement and implantation of a left ventriculoaortic shunt was initiated immediately after an emergency cesarean section.

Adult↗
PubMed1985

Configuration of the fetal electrocardiogram in ambulatory women in labor monitored with wideband telemetry.

The fetal electrocardiogram (ECG) in 23 ambulatory women in labor was monitored successfully with a single-channel FM telemetry unit with a 0.5-100-Hz wideband receiver to improve the quality of the ECG complex. An inverted QRS complex was seen in a patient with a deceleration and an inverted T wave during a deceleration in a patient confined to bed. A maternal artifact was transmitted in a third. The ECG complex was identical when wired patients were switched to telemetry. Thus, fetal heart rate and ECG configuration can be monitored accurately in ambulatory pregnant women.

Ambulatory Care↗
PubMed1984

Tocolysis with terbutaline sulfate in patients with placenta previa complicated by premature labor.

Six patients with placenta previa complicated by premature labor underwent tocolysis with terbutaline sulfate. The average prolongation of pregnancy was 3.5 weeks. Five patients were at 31 weeks' gestation or more at the initiation of tocolytic therapy and had infants who survived and were greater than 2,000 gm at birth. All patients received an average blood transfusion of 6.7 units of packed cells each.

Blood Transfusion↗
PubMed1981

Pregnancy complicated by concurrent primary hyperparathyroidism and pancreatitis.

The third case of pancreatitis and primary hyperparathyroidism during pregnancy is reported. The patient became gravely ill with "hypercalcemic crisis" in the third trimester, the condition was stabilized by medical therapy, and the fetus was delivered when mature. This combined diagnosis is difficult to make because of the changes in calcium metabolism that accompany pregnancy and because of the opposite effects the 2 diseases have on blood calcium levels. In early pregnancy, surgical management of the parathyroid disease seems warranted after the condition has stabilized, whereas in late pregnancy medical treatment may be used and definitive surgery may be postponed until after delivery.

Acute Disease↗
PubMed1980

Fetal heart rate variability as an indicator of fetal status.

Numerous studies have shown the clinical usefulness of monitoring fetal heart rate (FHR) variability. Among the disorders associated with decreased FHR variability during labor are fetal asphyxia and acidosis and subsequent distress in the newborn. Among the factors that influence FHR variability are maternal fever, fetal immaturity, so-called fetal sleep, fetal tachycardia, and drug administration to the mother. The nonstress test, which analyzes FHR variability and accelerations of heart rate with fetal movements, may be as useful as the oxytocin challenge test for assessing FHR variability. Doppler ultrasonic cardiography exaggerates the amount of FHR variability. FHR patterns associated with progressive loss of beat-to-beat variability in the absence of maternal drug intake necessitate intervention.

Electrocardiography↗
PubMed1980

Antepartum measurement of the preejection period in high-risk pregnancy.

The preejection period (PEP) of the fetal heart was measured in the antepartum period in 32 high-risk patients between 32.5 and 42 weeks' gestation. Successful measurements were made 70% of the time using an abdominal electrocardiogram and a single-crystal Doppler ultrasound transducer with narrow band-pass amplifier. PEP was found to correlate directly with gestational age (GA) and inversely with fetal heart rate (FHR). Three of 4 growth-retarded infants and another infant who was asphyxiated at birth had significant shortening of PEP prior to delivery.

Cardiac Output↗
PubMed1980

Anencephaly, twins and HLA-B27.

A patient with a twin pregnancy where both infants were affected with anencephaly is reported, and the world's literature on anencephaly in twins is summarized. The anomalies were diagnosed by ultrasound during the prenatal period. Studies of the genetic histocompatible lymphocyte antigens (HLA) types of both parents were performed, and they failed to demonstrate the HLA-B27 locus in either. Anencephaly in twins is an unusual phenomenon, with concordance even more rare. The possibility that anencephaly is a heterogeneous entity, both morphologically and genetically, and its relationship to the HLA locus are discussed.

Adult↗
PubMed1979

Post-traumatic coma during pregnancy.

A pregnant woman suffered massive head injuries in an automobile accident at 6 weeks' gestation, but she successfully carried the fetus an additional 7 months. The patient remained comatose and required nasogastric feeding and skilled nursing care. The pregnancy was complicated by a persistent low-grade fever. Premature labor began at 34 weeks' gestation, and 24 hours after rapid vaginal delivery of a live 1640-g female, the mother suddenly died. The child is developing normally at 2 years.

Accidents, Traffic↗