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Biomedical subjects

M B Selcuk

Publications and source records attributed to M B Selcuk.

5 recordsLinked to original sources

Contrast-enhanced power Doppler US in the diagnosis of acute appendicitis.

INTRODUCTION/OBJECTIVE: To determine the value of power Doppler (PD) ultrasonography (US) and contrast-enhanced power Doppler (CEPD) US in the diagnosis of acute appendicitis and the prediction of histopathologic stages. METHODS AND MATERIAL: 50 patients with suspected acute appendicitis were evaluated by the same radiologist with PD US and CEPD US. Air micro bubbles stabilized by a granulate of "galactose and palmitic acid" were used as a contrast medium for sonography with the concentration of 400 mg/ml. PD US and CEPD US results were later correlated with the surgical and histopathologic findings. PD US and CEPD US findings were considered positive for appendicitis; if there was depiction of hyperemia in the wall of the appendix or if there was depiction of prominent peripheral vascularity when compared with normal soft tissues; and negative if both hyperemia and peripheral hyperemia were not prominent. RESULTS AND DISCUSSIONS: Of the 50 patients, 35 patients had histopathologically proven acute appendicitis. CEPD US showed prominent hyperemia in the appendiceal vessels or feeding vessels of the inflamed appendix, and resistance index (RI) calculations were easier. There was statistically significant difference between mean RI values of the normal appendix, suppurative appendicitis and gangrenous appendicitis. PD US has accuracy of 80%, sensitivity of 74% and CEPD US has 98%, and 100% in the diagnosis of acute appendicitis. CEPD US identified 100% of suppurative appendicitis and gangrenous appendicitis. CONCLUSION: CEPD US is a promising method in the diagnosis of acute appendicitis and determination of the inflammation stage.

Acute Disease↗

Acute appendicitis: MR imaging and sonographic correlation.

OBJECTIVE: Acute appendicitis is the most common indication for emergency abdominal surgery. To our knowledge, MR imaging has not been compared with sonography for revealing acute appendicitis. Our aim was to assess and compare the accuracy, advantages, and limitations of MR imaging and sonography in revealing appendicitis. SUBJECTS AND METHODS: The study included 60 consecutive patients suspected of having appendicitis who underwent abdominal sonography and MR imaging. Fat-suppressed T2-weighted fast spin-echo and gadolinium-enhanced fat-suppressed T1-weighted spin-echo axial and coronal images were obtained. The initial MR imaging and sonographic studies were later correlated with the surgical-pathologic findings, follow-up evaluations, and diagnosis at the time of discharge. RESULTS: Surgical, histopathologic, and follow-up results revealed that 34 patients had appendicitis. Of the 26 patients without appendicitis, 15 with symptoms of acute appendicitis had no pathologic diagnoses and the remaining 11 had another diagnosis. Comparison of the sensitivity, accuracy, and negative predictive values for MR imaging and sonography was found to be statistically significant (p < .05, chi-square test), indicating that MR imaging was superior to sonography in revealing appendicitis. We found no statistical difference in specificity and positive predictive value for MR imaging and sonography. CONCLUSION: Despite some disadvantages, we found MR imaging to be superior to sonography in revealing suspected acute appendicitis. MR imaging can be used after suboptimal or nondiagnostic sonography in cases of suspected acute appendicitis.

Acute Disease↗

Intracystic application of mebendazole solution in the treatment of liver hydatid disease. Preliminary report of two cases.

Mebendazole, a derivate of benzimidazole, is commonly used for the treatment of hydatid disease in patients at high operative risk and/or to prevent secondary hydatidosis. In this study, 2 cases of liver hydatid disease, in which mebendazole was used both orally and for intracystic application are presented. These cases have been treated by percutaneous drainage and videolaparoscopic methods. Mebendazole solution at a concentration of 2.4 micrograms/ml was injected into the cyst. For a period of 6 months 50 mg/kg/day oral treatment was given. At the end of a 6- to 9-month period, the total recovery was observed. This is the first report of mebendazole pair-treatment in the literature.

Adult↗

Computed tomography in agenesis of the right lobe of the liver.

Congenital agenesis of the right lobe of the liver is a rare anomaly. In a case report the diagnosis was made by computed tomography. A retro- or suprahepatic location of the gallbladder and compensatory hypertrophy of the left liver lobe and/or caudate lobe may give support to the diagnosis. Before diagnosing congenital agenesis of the lobe, lobar atrophy due to cirrhosis, cholangiocarcinoma or any other predisposing conditions should be eliminated.

Cholecystography↗