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Biomedical subjects

M B Shtark

Publications and source records attributed to M B Shtark.

15 recordsLinked to original sources
PubMed1979

[Localization of neurospecific protein-antigens on the surface membrane of neurons and glia of grape shails].

The existence of cross (common) proteins-antigens on the membrane of nervous and glial cells of Helix pomatia in vitro was proved by Coons' method of immunofluorescence. The presence of the neurospecific protein S-100 on the membrane of these cells and antigenous heterogeneity of the membranes of the neuronal cell population were established. The antigen concentration was shown to vary on the somatic and axonal membranes. The distribution pattern of specific luminescence indicates potential qualitative and/or quantitative differences in the content of neurospecific proteins in various portions of the neuronal membrane.

Animals↗
PubMed1977

[Electroencephalographic effects of the intracentral administration of antibodies to brain-specific antigen S-100].

The EEG method with the assessment of the rhythm power on analogue computers was used to examine the effects of intracentral administration of antibodies to the brain-specific antigen S-100 (S-100 protein). Intracerebral injections of antibodies to S-100 protein caused an increase of the EEG basic rhythm power in the hippocampus, caudate nucleus and the mesenphalic reticular formation, with the subsequent development of epileptiform activity in these structures.

Animals↗
PubMed1977

[Morphology of the horn of Ammon of the rat hippocampus in tissue culture].

By using the light- and electron microscope methods some morphogenetic properties of rat hippocampus were studied in tissue culture (field CA1--2). Analysis of 5-, 12-, and 21-day cultures showed maturation of hippocampal- pyramid cells, development of protein-synthesizing apparatus and synaptogenesis. The authors consider synchronous development of synaptic structures, protein-synthesizing apparatus and electrogenesis to be interdependent factors.

Age Factors↗
PubMed1976

A comparative statistical study of hippocampal neuronal spontaneous spike activity in situ and in vitro.

The statistical characteristics of the spontaneous spike activity of rat hippocampal neurons in fields CA1-2 were compared in situ and in tissue culture. Statistical analyses have shown strong similarities in estimators of basic numerical characteristics of interspike interval (SIS) distributions. These similarities may serve as evidence of maintenance of normal functional properties and an "organotypic arrangement" of neurons in tissue culture, and they are also indicative of an intrahippocampal origin of the spontaneous impulse activity in the hippocampus. On the other hand, some differences are noted in the tests of firing patterns. Interpretation of these results leads to some assumptions about mechanisms of the phenomenon under study.

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