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Biomedical subjects

M Bågedahl-Strindlund

Publications and source records attributed to M Bågedahl-Strindlund.

17 recordsLinked to original sources
PubMed2005

A longitudinal study of psychiatric symptoms in primiparous women: relation to personality disorders and sociodemographic factors.

OBJECTIVE: To examine the prevalence of personality disorders (PDs) and elucidate the importance of PDs, sociodemographics and health-related factors for the development of psychiatric symptoms in primiparous women. METHOD: 625 primiparous women were assessed during pregnancy, three and 18 months following delivery. The Symptom Checklist-90 (SCL-90), the modified SCID-screen questionnaire and the Global Assessment of Functioning Scale (GAF) were used. RESULTS: The prevalence of PDs was 6.4%. PD was strongly associated with psychiatric symptoms during and after pregnancy. The most important factor predicting long-lasting mental problems was having a PD. A higher level of psychiatric symptoms was found in pregnancy than postpartum. Psychiatric caseness during pregnancy was strongly associated with caseness postpartum. In addition, socio-economic status, younger age and previous treatment for mental problems were identified as risk factors. CONCLUSION: The study indicates a strong association between long-lasting psychiatric illness and personality disorders in childbearing women. A strong association was also found between psychiatric symptoms during pregnancy and the postpartum period.

Adult↗
PubMed1998

A multidisciplinary clinical study of patients suffering from illness associated with release of mercury from dental restorations. Medical and odontological aspects.

OBJECTIVE: To describe medical and odontological aspects of patients who believed their illness was caused by mercury in dental fillings. DESIGN: Comparison of self-reported and assessed medical and odontological variables. SETTING: The School of Dentistry, Karolinska Institute. SUBJECTS: Sixty-seven patients, referred for suspected side-effects of mercury in dental fillings, and 64 matched controls. MAIN OUTCOME MEASURES: Incidence of medical and odontological diagnoses, own perception of health, and incidence of self-reported symptoms. RESULTS: Three quarters of the patients were women. The mean age was 49 years. Thirty-seven patients (55%) and 47 controls (73%) (NS) showed no sign of somatic disease. Half of the patients felt ill or very ill at the time of the examination. Patients reported twice as many symptoms as the controls during a 3-month period. Patients reported a higher prevalence of very low resting saliva secretion rate, and a higher number of decayed tooth surfaces and of instances of temporomandibular joint dysfunction. CONCLUSION: Patients' feelings of ill-health were more likely related to psychiatric than somatic diagnoses. This study underlines the importance of making an overall diagnosis, including both mental and somatic disorders, especially in unclear cases and in self-diagnosed illnesses.

Attitude to Health↗
PubMed1998

Postnatal depression: a hidden illness.

The main objectives of this study were (i) to find out to what extent postnatal depression (PND) in mothers was recognized at Well Baby Clinics (WBCs) in Stockholm, (ii) to study the prevalence of PND using the Edinburgh Postnatal Depression Scale (EPDS), (iii) to test the positive predictive value of the EPDS against an interview-based Research Diagnostic Criteria (RDC) diagnosis of depression and (iv) to identify sociodemographic risk factors for PND. Case-records of 1128 infants were reviewed at WBCs to obtain a baseline rate of PND. Two per cent of the mothers were identified in the routine service of the WBCs as being depressed during the first 3 months postpartum. During a project year, 309 Swedish-speaking mothers completed a set of EPDS 3 months postpartum. In total, 14.5% of the women scored > 12 on the EPDS and 67% of these women had a depression according to RDC. At least 8.4% of the mothers investigated had a clinical depression. A positive link was found between being single with more than one child and having PND. In conclusion, very few women with PND are identified in routine WBC care in Sweden. The use of the EPDS as a screening measure at the WBC is recommended. The scale is well accepted both by the mothers and by the nurses, and its use significantly increases the number of identified cases of PND.

Adult↗
PubMed1997

Parapartum mental illness: an interview follow-up study.

A total of 54 parapartum mentally ill mothers and 89 controls were followed up approximately 6 years after childbirth. In total, 80% of the patients avoided further pregnancies during the follow-up period, compared to 58% of the controls (non-significant difference). One-third of the patients did not live together with their child, compared to only 3% of the controls. Index mothers tended to report more problematic relationships with their children. Poor childhood relationships during the mother's own childhood seem to be of special significance for the development of these problems. This study suggests a rather gloomy prognosis for parapartum mental illness. The suicide rate was 4.5%. In total, 22% of the patients, compared to none of the controls, had been on sick leave during the last 3 years, or had received a disability pension owing to mental illness at the time of the follow-up. The readmission rate for psychiatric in-patient care was 46% in the patient group.

Case-Control Studies↗
PubMed1997

A multidisciplinary clinical study of patients suffering from illness associated with mercury release from dental restorations: psychiatric aspects.

The aim of this study was to map the psychological/psychiatric, odontological and medical aspects of patients with symptoms allegedly related to the side-effects of mercury in dental fillings. A total of 67 consecutive patients and 64 controls matched for age, sex and residential area were included in the study. The most striking result was the high prevalence of psychiatric disorders in the patients (89%) compared to the controls (6%), predominantly somatoform disorders. The personality traits differentiating the patients according to the Karolinska Scales of Personality (KSP) were somatic anxiety, muscular tension, psychasthenia and low socialization. More patients than controls showed alexithymic traits. The prevalence of diagnosed somatic diseases was higher, but not sufficiently so to explain the large difference in perceived health. The multiple symptoms and signs of distress displayed by the patients could not be explained either by the odontological data or by the medical examination. Our data indicate that the patients show sociodemographic and clinical patterns similar to those of somatizing patients. The medicalization of the suffering of these patients and the neglect of psychiatric problems prevent the use of appropriate psychotherapeutic approaches.

Adolescent↗
PubMed1994

Biochemical hyperparathyroidism and bone mineral status in patients treated long-term with lithium.

Lithium is known to interfere with normal calcium homeostasis, but the long-term effects and possible clinical significance are uncertain. Thus, we measured indices of parathyroid function including intact parathyroid hormone (PTH) and ionized and total calcium levels in 26 patients treated for manic-depressive psychosis with lithium for 10 years or longer (mean +/- SD duration, 15 +/- 6 years). Increased ionized calcium levels were found in 11 patients and increased PTH concentrations in five patients. Altogether, 54% of the patients (14 of 26) had ionized calcium and/or PTH levels above the laboratory reference range. The PTH/ionized calcium relationship of the lithium-treated patients was compared with that of a group of normal subjects (n = 23) and with those of three different groups of patients with abnormal parathyroid function (chronic hypoparathyroidism, n = 21; primary hyperparathyroidism [HPT], n = 50; and tertiary HPT, n = 21). Lithium-treated patients had significantly higher ionized calcium levels (P < .0001) but not significantly higher PTH concentrations (P = .08) than the normal subjects. In comparison to the normal controls, lithium-treated patients had a right-sided shift in their PTH/ionized calcium relationship that was in the same direction but less prominent than in primary or tertiary HPT. Dual-energy x-ray absorptiometry disclosed similar bone mineral densities (BMDs) of lithium-treated patients and age-, sex-, and body mass-matched normal controls in the whole body, lumbar spine, and femoral neck (Z scores: +1.20, +1.22, and +1.02, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1992

Hyperparathyroidism associated with treatment of manic-depressive disorders by lithium.

OBJECTIVE: To clarify the association between treatment of affective psychiatric disorders with lithium, and the development of secondary hyperparathyroidism. DESIGN: Retrospective review of medical records, 1973-89. SUBJECTS: 17 patients with affective psychiatric disorders who were treated with lithium (n = 6) or with tricyclic antidepressant, or neuroleptic, drugs (n = 11) all of whom were operated on for hyperparathyroidism. MAIN OUTCOME MEASURE: Duration of lithium therapy and parathyroid histology. RESULTS: Parathyroid hyperplasia was present in 5 patients who had taken lithium during a median period of 13 years. A parathyroid adenoma was found in one patient treated with lithium for three years. Ten of the 11 patients who had been treated with tricyclic antidepressant, or neuroleptic drugs had a parathyroid adenoma and the remaining one had an adenoma as an underlying cause of hyperparathyroidism. CONCLUSION: Hyperparathyroidism in patients who have undergone long term treatment with lithium is associated with parathyroid hyperplasia. This indicates that lithium may exert a chronic stimulus that results in secondary hyperparathyroidism.

Adenoma↗
PubMed1989

Children of mentally ill mothers: social situation and psychometric testing of mental development.

Children of mothers who satisfied the Research Diagnostic Criteria of (1) Schizophrenia, (2) Alcoholism or Drug Use Disorder, (3) Major Depressive Disorder including Mania, (4) Unspecified Functional Psychosis, and (5) Other Psychiatric Disorder and children of obstetric controls were studied with regard to subsequent mental and behavioural development and social conditions. 72 index children and 17 children from the comparison group were examined at an approximate age of six years by a child psychologist. More index children than those from the comparison group showed impaired mental and behavioural development. The children of abusing mothers in particular tended to have a worse outcome. One-half of the index children were not living with their mothers at the time of follow-up.

Child↗
PubMed1988

Children of mentally ill mothers: mortality and utilization of paediatric health services.

A two-year cohort of children of parapartum mentally ill mothers, born in Stockholm during the mid-1970s, was studied with regard to mortality, hospitalization rate and Well Baby Clinic (WBC) care consumption during the pre-school-age period. The findings were compared with those of matched controls. The index children-especially those of addicts and neurotic or temporarily insufficient mothers-had a higher admission rate and had spent more days in hospital than the controls. The index children tended to have a higher mortality rate than the controls. No significant difference was found in the WBC attendance rates of the index children and the controls. Socially disadvantaged families tended, however, to pay more visits to the WBC than those who were better off. Home visits by the WBC nurse were made more frequently to the index families than to the controls. Failure to appear for regular health checks of the child correlated better with social dysfunction than with mental illness per se in the mother. An adverse social environment, including addiction, seemed to be a separate factor of significant importance, apart from mental illness per se in the mothers, for the morbidity of the children.

Child Health Services↗
PubMed1988

Mentally ill mothers and their children. A controlled study of social welfare utilization.

177 cases of parapartum mental illness and 173 matched obstetric controls were studied retrospectively from the perspective of the social welfare services (SWS). Data covering five years before the index partus until five to seven years thereafter, were studied. Parapartum mentally ill women were known to the SWS to a much greater extent (75%) than their matched controls (33%). They also presented more severe environmental problems than their matched controls. Within the index sample the largest number of adverse factors known to the SWS was found in the addicts and NTI (neuroses and temporary insufficiencies) groups. The dysfunction in the families appeared to be constant throughout the observation period. A large proportion of the index children (32%) had been placed in foster care or adopted. When the index women had applied to the SWS during the first postpartum year the social workers were informed of the fact that she had contacted a psychiatric department in 8 out of 10 cases. However, only in half of these cases had regular collaboration taken place. Collaboration was far more frequent when the mother suffered from severe mental illness than when she was suffering from a less severe mental disturbance.

Humans↗
PubMed1988

Children of mentally ill mothers: mental development, somatic growth and social outcome.

A two-year cohort of children of parapartum mentally ill mothers born in Stockholm during the mid-70s was studied with regard to mental development, somatic growth and social outcome. The observation period covered the pre-school-age period and the study was based on Well-Baby-Clinic (WBC) data. The findings were compared with those of matched controls. Nearly 40% of the children of the mentally ill mothers, compared to 3% of the controls, did not live with their biological mothers during the pre-school ages. No difference was found in somatic growth between the index and control children. However, more index children--especially those of addicts and neurotic or temporarily insufficient mothers--than controls suffered from developmental (p less than 0.05) and behavioural (p less than 0.001) disturbances. Fifteen per cent of the index children compared to 5% of the controls were judged by the staff of the WBC to be in need of treatment for psychological problems (p less than 0.01). The results of the present study emphasize the fact that children of mentally ill mothers constitute a high-risk group regarding mental and behavioural development. The study supports earlier research reports claiming that, while parental mental illness constitutes an important indicator of psychiatric risk for the children, the main risk stems from associated psychosocial disturbances in the family.

Child↗
PubMed1986

Mentally ill mothers and their children. An epidemiological study of antenatal care consumption, obstetric conditions, and neonatal health.

Antenatal care consumption, obstetric conditions, and neonatal health, were studied retrospectively in all women in the county of Stockholm who had a baby during 1976-77 and also had been admitted to a psychiatric department after the 20th week of pregnancy or within the first postpartum year, and the findings were compared in matched obstetric controls. Fewer index women had had uncomplicated pregnancies than the controls. A positive relationship was found between acute mental illness and pregnancy complications. Delivery complications tended to to be more common in the index group than in controls, but, only in patients with prepartum onset of mental illness. More index women had a history of several previous abortions than the controls. The index women, and especially the addicts, attended the antenatal care clinics significantly less frequently than the controls. The neonatal health of the index children seemed to be more closely correlated with alcohol or drug dependency per se in the mothers than with mental illness.

Abortion, Legal↗
PubMed1986

Parapartum mental illness: timing of illness onset and its relation to symptoms and sociodemographic characteristics.

Clinical pictures and certain sociodemographic factors were studied retrospectively in all women in the county of Stockholm who had a baby during 1976-77 and also had been admitted to a psychiatric department after the 20th week of pregnancy or during the first postpartum year. The sample was classified according to the Research Diagnostic Criteria. A significant rise in the incidence of mental illness was found within the first 3 months postpartum and particularly so within 1 month postpartum as compared with during pregnancy and the following 9 months. This peak in incidence was due to a rise in the number of women classified as Unspecified Functional Psychosis. The nosology of postpartum psychosis is discussed. An increased frequency of neurotic or minor psychiatric disorders was noted during pregnancy as compared with the first 3 months postpartum and the following 9 months. No associations were found between the sociodemographic factors considered and the time of illness onset, although marital discord tended to be more frequent in women with onset of illness during pregnancy.

Adolescent↗
PubMed1983

Does the season of conception influence the frequency of post partum mental illness?

The study is based on two series of patients with post partum mental illness, one consisting of 71 women in Gothenburg 1952-56 and another of 68 women in Stockholm 1976-77. The total number of births in the two cities during the periods in question were used as reference. A strategy of chi-squared test and the Edwards' criteria of seasonality was applied for statistical analyses of the results. A yearly double periodic trend in month of conception could be observed.

Adult↗
PubMedDate not supplied

Children of parapartum mentally ill mothers: a follow-up study.

A 2-year cohort of children (n = 75) of hospitalised first-episode parapartum mentally ill mothers in the mid-1970s in Stockholm were studied. The children were followed up during the school-age period from 1982 through 1992, and they were studied with regard to health development, academic achievement and family situation. Comparisons were made with matched controls. Data were collected from hospital case notes, the local tax authorities and school reports. No significant differences were found between the index children and the controls regarding the number of inpatient care episodes or days of inpatient care during the follow-up period. Nor was any significant difference found between the index and the control children regarding academic achievement as measured by the mean of all marks. Four index children and 2 controls were studying in schools for the mentally retarded. Seventy-four percent of the children of the patients were living with their mother, compared to 95% of the controls (p < 0.001). In conclusion, the children of mentally ill mothers in this longitudinal study did as well as the controls. The reason might be the social support provided by society (when needed) for these high-risk families in Sweden.

Adolescent↗