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Biomedical subjects

M Bély

Publications and source records attributed to M Bély.

67 records · Page 4Linked to original sources

Aseptic bone necrosis.

The post-traumatic and vascular necrosis of broken bones were studied in rabbits. AFter experimental traumatization and vascular lesion a similar type of necrosis was encountered. There were, however, differences in the distribution of the necrotic areas and in the position of the fracture-line. In the case of post-traumatic necrosis the fracture line was situated at the border of the intact and the necrosed tissue, whereas in vascular necrosis of secondarily broken bones it was found in the necrobiotic area. Surveying morphometrically the distribution of necrotic areas it was observed that in traumatic necrosis large fields occur on either side of the fracture-line which retained in 95% the nuclear staining of their osteocytes while in vascular necrosis such areas were not seen. On this basis traumatic and vascular necrosis can be differentiated provided the sample is taken from the surroundings of the fracture-line.

Animals↗

A histochemical study with the aBt reaction of changes in glycoprotein content during bone formation and necrosis.

The glycoprotein content of the bone tissue was examined by means of the aldehyde-bisulphite-blue (ABT) reaction. It was found that the glycoprotein content showed variations during bone formation and necrosis. This was particularly characteristic in the osteocyte capsule where vicinal OH moieties changed in amount and orientation. The method allows to determine the relative age of the bone tissue.

Aldehydes↗

The study of bone tissue with new argyrophilic techniques.

Fractured and necrotic bones were examined by new silver impregnation techniques based on the catalytic activity of the bone. The new methods proved to be useful in differentiating between bone tissues of various ages and maturity and between living and necrotic bones.

Alcohols↗

Early diagnosis of cancer by gastricbiopsy.

On the basis of 350 gastric biopsies the difficulties of early diagnosis of cancer are discussed. The technical and morphological stumbling blocks of evaluation are reviewed. The differences between the gross and microscopic diagnoses, the more important causes of histologic error are dealt with.

Adenocarcinoma↗

Angiooedema due to acquired deficiency of C1-esterase inhibitor associated with leucocytoclastic vasculitis.

A hereditary and an acquired type of C1-esterase inhibitor deficiency have been described. Manifestations characteristic of both forms include recurrent subcutaneous and submucosal angiooedema. Acquired C1-esterase inhibitor deficiency has been observed in association with lymphoproliferative disorders, malignancy, autoimmune diseases and infections. We report on a case with the acquired form of the disease accompanied by leucocytoclastic vasculitis. Treatment with antimalarial agents resulted in complete resolution of symptoms and signs. Furthermore, C1-esterase inhibitor concentration and activity, as well as C1 levels, all returned to normal.

Adult↗

[Relation between histologic-bioptic findings in the synovial membrane and the clinical results of therapy in subsequent chemical synovectomy].

The histological findings in needle biopsy specimens from 35 patients suffering from chronic exudative synovitis of the knee were compared with the clinical data and with the results of chemical synovectomy carried out after the needle biopsy. The investigations suggest that in cases with the pronounced histological changes less improvement can be expected from chemical synovectomy than in cases with slighter histological changes.

Adolescent↗