[Pseudothrombocytopenia].
On the basis of literature data we have tried to present contemporary views on pseudothrombocytopenia (PTCP), especially EDTA-dependent pseudothrombocytopenia. False thrombocytopenia is caused by in vitro platelet clumping in EDTA-anticoagulated blood. Electronic blood count shows a low platelet count in subjects with normal platelet levels. The mechanism of this reaction appears to involve antiplatelet antibodies against glycoprotein IIb. The best technique for obtaining accurate platelet counts in PTCP subjects is to collect and examine blood sample at 37C.
Diagnosis, Differential↗