Biomedical subjects

M BJORNEBOE

Publications and source records attributed to M BJORNEBOE.

17 recordsLinked to original sources

PubMed1965

[DRUG TREATMENT OF LIVER CIRRHOSIS].

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Diuretics↗

PubMed1964

GAMMA GLOBULIN TURNOVER IN RABBITS BEFORE AND DURING HYPERIMMUNIZATION.

The turnover of (131)I-labeled gamma globulin has been determined in rabbits before and during (8 weeks later) hyperimmunization with pneumococcic vaccine, which increased the gamma globulin concentration 5 to 10 times. Before immunization fractional turnover rate was an average of 36 per cent of the plasma pool per day, and the rate of catabolism was 133 mg/kg/day. During hyperimmunization fractional turnover rate was an average of 37 per cent per day, and the rate of catabolism was 1160 mg/kg/day. The observation that the fractional turnover rate is independent of the concentration suggests that the rate of breakdown should have the characteristic of a first order process.

Animals↗

PubMed1962

[Adrenocortical hormone treatment of cirrhosis].

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Adrenal Cortex Hormones↗

PubMed1959

Investigations concerning the changes in serum proteins during immunization; the cause of hypoalbuminemia with high gamma globulin values.

On hyperimmunization of rabbits with pneumococcal vaccine, increase in the content of gamma globulin and fall of albumin in the serum are produced. In such hyperimmunized rabbits, investigations of the plasma volume, albumin degradation, and the distribution of the albumin intra- and extravascularly were undertaken by Sterling's method employing rabbit albumin labelled with I(131). The investigations do not suggest any significant alteration in the albumin degradation nor in the distribution between the intra- and extravascular albumin. It was demonstrated that the plasma volume increases simultaneously with increase in the gamma globulin and fall in albumin. It is concluded that the fall in serum albumin observed is due to a regulative mechanism which attempts to maintain the colloid-osmotic pressure by increasing the plasma volume.

Animals↗

PubMed1958