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Biomedical subjects

M Bacchini

Publications and source records attributed to M Bacchini.

At least 19 recordsLinked to original sources
PubMed1990

Isolation in Italy of a verotoxin-producing strain of Escherichia coli O157:H7 from a child with hemolytic-uraemic syndrome.

Verotoxin-producing Escherichia coli O157:H7 was isolated for the first time in Italy from a child with hemolytic-uremic syndrome and his asymptomatic sister. Both parents remained asymptomatic, and neither had evidence of this infection. The source of the infection was not identified, but the children had eaten ground beef during the 15 days prior to the onset of symptoms.

Bacterial Toxins↗
PubMed1984

Double-blind placebo-controlled trial of baclofen, alone and in combination, in patients undergoing voluntary abortion.

This study evaluated the analgesic efficacy of baclofen in relation to specific pain stimuli in 83 women (27 nulliparas and 56 multiparas) undergoing voluntary abortion (clamping of the cervix and dilatation and curettage). The patient population was divided into five treatment groups as follows: group 1, placebo; group 2, baclofen, 0.3 mg/kg, administered intravenously (IV); group 3, baclofen, 0.6 mg/kg IV; group 4, baclofen, 0.3 mg/kg IV, and fentanyl, 1.5 mg IV; and group 5, baclofen, 0.3 mg/kg IV, and diazepam, 5 mg given orally and 5 mg IV. In each case the surgical intervention was started using analgesia only. When the first sensation of pain was recorded, a paracervical anesthetic block was performed to provide pain relief for completion of the operation. The results showed that baclofen had significantly better analgesic properties than did placebo, with no important side effects. Its analgesic action seemed to be dose-dependent, since better results were obtained with the higher dose. The analgesic effect was slightly potentiated when baclofen was combined with fentanyl, but not when it was combined with diazepam. Factors independent of the pain stimuli and drugs used--the most important being parity--influenced the results.

Abortion, Induced↗
PubMed1979

[Circulatory disorders and acupuncture].

The present study was designed to examine whether acupuncture is useful in the treatment of some disorders of the vascular system as the thromboangiitis obliterans of the extremities, the Raynaud's disease and in the therapy of ulcers by venous stasis. From the data presented it appears that acupuncture is effective in releasing the arterial spasm and especially in increasing the circulation in collateral vessels. In order to prove the efficiency of acupuncture in the above disorders, the response to acupuncture was compared with that obtained by a pharmacological treatment with lumbar paravertebral block.

Acupuncture Therapy↗
PubMedDate not supplied

Blount's disease.

Out of a total of 40 patients affected with Blount's disease treated at the Pediatric Orthopaedic Division of the Rizzoli Orthopaedic Institute between 1965 and 1996, 29 were affected with the infantile type, and 11 with the adolescent type. In the group affected with infantile Blount's disease, the mean age was 5.5 years, 11 were bilateral, for a total of 40 limbs affected, with a mean TMD angle of 24 degrees. All of the patients were treated by valgus osteotomy obtaining a percentage of poor results (insufficient correction or recurrence) equal to 25% according to Schoenecker's criteria. Mean follow-up was 3.6 years. In the group affected with adolescent Blount's disease, mean age was 12.6 years, the affection was always monolateral, the mean TMD angle was 15 degrees. All of the patients except 1 were treated by valgus osteotomy with elevation, and the results were constantly favorable. Mean follow-up was 2 years. The authors believe that the type of osteotomy used must be modulated based on the anatomopathologic findings of compromise in the proximal tibial metaepiphysis.

Adolescent↗
PubMedDate not supplied

Post-traumatic reflex sympathetic dystrophy in the ankle and foot: a study of 32 cases.

The etiopathogenesis of reflex sympathetic dystrophy is still undefined, and diagnosis and treatment are difficult. It is the purpose of this study to propose precise diagnostic and therapeutic criteria for post-traumatic reflex sympathetic dystrophy of the ankle and foot. Diagnosis is pre-eminently clinical. Clinical progression of the disease occurs in three stages: acute, dystrophic, chronic. Radiographic examination cannot be used to classify the stage of the syndrome. Bone scan with Tc 99M methylendiphosphonate aids diagnosis, and helps establish the prognosis of the disease. Clinical symptoms and instrumental tests (x-ray, bone scan, CT scan, MRI) are discussed in relation to differential diagnosis with other pathologies of the ankle and foot. Furthermore, the effective use of drugs, physiokinesitherapy, and hyperbaric oxygen therapy is discussed. The authors present a study of 32 patients, paying close attention to early clinical signs of the disease. X-ray examination and bone scan were routinely carried out in established diagnostic protocols.

Adult↗
PubMedDate not supplied

Growth evaluation in children with acute renal failure of unknown etiology.

We performed a retrospective study on 47 children over 1 year of age with severe acute renal failure (ARF) treated with hemodialysis (HD) at our Center from 1978 to 1986 in order to evaluate the diagnostic and prognostic value of growth indexes at hospital admission as a criterion to distinguish cases of ARF without previous chronic renal failure (CRF) from cases in which CRF was not previously diagnosed. The age of the patients ranged from 17 months to 13 years. The cause of ARF was identified in 41 children; 5 of them remained on HD for different reasons (hemolytic uremic syndrome with arteriolar involvement in 3 cases; renal vein thrombosis in 1; endoextracapillary glomerulonephritis in 1). No apparent cause of ARF was found in the other 6 children who remained on chronic HD. A careful history showed that these 6 children had had uremic symptoms for many years. When height was expressed as height standard deviation score (HSDS), the 6 children with ARF of unknown etiology showed significantly lower HSDS values compared with the other 41 children in whom a cause of ARF was diagnosed (p less than 0.001). In conclusion, growth failure in children requiring HD for ARF of unknown etiology is an important criterion that suggests a previously undiagnosed CRF and thus consequently a negative long-term prognosis.

Acute Kidney Injury↗