Disseminated dermatophytic pseudomycetomas arising in an immunocompromised patient.
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Biomedical subjects
Publications and source records attributed to M Balabanova.
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BACKGROUND: The type and frequency of different manifestations of Behçet's disease (BD) vary in different geographic areas. This variability could affect the ability to diagnose the disease in certain areas by using standardized criteria. The frequency of cutaneous lesions in patients from the United States, where the disease is less prevalent, is not known. OBJECTIVE: We sought to determine the frequency and type of skin lesions in a series of patients with BD from the United States and to identify methods of confirmation of these lesions as part of the disease process. RESULTS: Cutaneous manifestations were present in 64% of patients with BD. Clinicians most often relied on their clinical diagnosis to identify lesions as part of the spectrum of BD. Skin biopsy specimens were generally nonspecific. CONCLUSION: Cutaneous manifestations were common in patients with BD from the United States and usually were necessary to fulfill the diagnostic criteria of the disease in most cases.
Scleroderma profunda represents an unusual clinical entity. There are no unified criteria for its diagnosis. Seven patients with scleroderma profunda were studied. The clinical features can be summarised in three groups: 1. hyperpigmented plaques with subcutaneous induration; 2. erythematous plaques with induration of the skin and subcutis; 3. pale indurated plaques with atrophy and sometimes ulcerobullous lesions. Histology showed sclerodermiform changes in the deep dermis and subcutis and vasculitis in one case. Dermal lymphocytic infiltration was well pronounced in 5 cases and consisted of predominantly CD3+ T cells. Differential diagnosis from panniculitis can be difficult. Mucin deposition was established in all cases.
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We describe 3 professional footballers who developed lichenoid dermatitis over a short period of time. Clinically, the eruption in all 3 of them can be classified as lichenoid photodermatitis. We suggest an influence of possible contact allergens or photo-active substances. Histologic evidence points to features of classical lichen planus with purpura, typical of lichen aureus (purpuricus), but showing some clinical and morphological differences.
The authors have studied the melanocytic population in oral mucosa (Dihydorxyphenyl alanine, silver impregnation, hematoxilin-eosin) of 20 patients (10 with Lichen ruber planus and 10 with Alopecia areata). The melanocytic population in oral mucosa ranges from 605 to 1555 cells per m2 (964 +/- 312 on the average). Normal population, in case of lichen planus of oral mucosa, is disturbed in the regions of the pathological process. The deviations established are discussed.