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M Barbara

Publications and source records attributed to M Barbara.

75 records · Page 5Linked to original sources

[Cytologic findings on chronic inflammatory disease of the vocal folds].

The usefulness of cytologic diagnosis in laryngeal pathology is still controversial, also in the cytopathologist's opinion. A sampling procedure such as routine cytodiagnosis can be considered useful for both diagnosis and treatment of non-surgically related laryngeal diseases. This study was designed in order to demonstrate how cytodiagnosis can be useful in etiologic and pathogenetic diagnosis of chronic non-specific inflammatory diseases of the vocal folds. Cytologic sampling was carried out on brushing material of simple and hyperplastic laryngeal inflammations and on normal vocarfolds which were used as control. Through cytologic examination it was possible to evidence specific morphological findings which allowed differentiation of not only healthy from diseased vocal cords, but also hyperplastic from simple inflammatory processes. Moreover, the high incidence of goblet cells and cylindric squamous metaplasia in hyperplastic corditis, as well as the frequent presence of fungal involvement in the simple forms, prompted the Authors to hypothesize pathogenetic mechanisms as well as progression inducing factors of the pathologies in question.

Carcinoid Tumor↗

[The surgery of the endolymphatic sac: a conservative or destructive procedure?].

A detailed analysis of different aspects relative to endolymphatic sac surgery employed as conservative surgical treatment in Menière's disease is presented. The presumed basic principles for this type of surgery, which have led several otologists to adopt this procedure in the therapeutical protocol followed in Menière's disease, are discussed along with the good symptomatological results obtained. Particular emphasis is put on the multiple functions which have been attributed to the endolymphatic sac in the functional dynamics of the entire inner ear environment. Among these functions, relevance is given to the secretory activity, which is presumed to be triggered by endolymphatic dysbarisms, which implies that macromolecules that are able to interact with fluid metabolism (glycosaminoglycans) might flow into the luminal endolymphatic space, a phenomenon which may well open new perspectives for the pathogenesis and treatment of Menière's disease. On the grounds of these premises, the conservative aspect of endolymphatic sac surgery, along with its mechanism of action, is reassessed.

Ear, Inner↗

[Anesthesiological methods in acoustic neuroma surgery using the translabyrinthine approach].

Removal of acoustic neuromas may often imply anesthesiological as well as surgical problems, especially in the case of large tumors (> 3 cm) which may have come into contact with vital neighbouring structures (brain stem, cerebellum). In this paper the use of two different anesthesiological methods during the translabyrinthine approach is analyzed and discussed in the light of the different needs in this type of surgery. More specifically, anesthesia maintenance was assured by constant infusion of either Propofol (4 mg/kg/h) or Isoflurane (1-1.5%). Withdrawal of curarization was also planned in order to allow the surgeon to take advantage of routine intraoperative facial nerve monitoring. Arterial pressure, CO2 and O2 were assessed at prefixed phases of the operation. Both anesthesiologic methods proved to be satisfactory during the entire surgical procedure. During dissection of the tumoral capsule, an increased heart rate (7% of the initial value) was noticed, whilst in only three patients (with tumors larger than 3.5 cm) a severe bradycardia, which did not respond to Atropine administration and which subsided spontaneously during temporary suspension of surgical manoeuvres, occurred. After this preliminary experience, the Authors believe that both techniques could have a major role in translabyrinthine acoustic tumor surgery and auspicate their further application.

Adult↗