[Peripheral neuron damage in periarteritis nodosa: diagnostic problems].
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Biomedical subjects
Publications and source records attributed to M Barcikowska-Litwin.
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A 47-year-old man is reported who had an extensive arteriovenous angioma of the spinal cord confirmed during operation. The patient had an atypical symptom complex, with clinically evident deep flaccid paresis of lower extremities without pyramidal signs, sensory disturbances and sphincter disturbances. The anomaly causing a steal mechanism led to ischaemia of the anterior horns of the cord.
A case of segmental spinal necrosis is described involving the area of supply of the sulcocommissural artery. The location of the necrosis and recurrent course of the disease suggest a vasogenic mechanism of the disease in the patient with atherosclerosis and hypertension.
The authors describe a case of hereditary neuropathy with increased sensitivity to pressure stressing its characteristic course facilitating the diagnosis. Electrophysiological investigations of the peripheral nerves demonstrated a generalized character of the disease process, morphological examination of the peripheral nerves demonstrated presence of characteristic although non-specific, limited myelin thickenings, different length of internodal segments, slight evidence of demyelination and remyelination, and presence of axonal component. The mechanism of development of these changes is still unexplained, possible myelinogenesis disturbances are discussed.
Two cases of venous strokes diagnosed on autopsy of fixed brain are described, one in a 54-years-old female with diabetes and hypertension, and another in a 78-years-old female. In both cases the course of the disease was very dramatic and in both thrombosis of the vena cerebri magna was found.